Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SGD-1882 is a agent of cytotoxic, DNA minor-groove crosslinking pyrrolobenzodiazepine (PBD) dimer, and acting as the payload for ADCs.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | 10-14 weeks | $ 2,390.00 |
Description | SGD-1882 is a agent of cytotoxic, DNA minor-groove crosslinking pyrrolobenzodiazepine (PBD) dimer, and acting as the payload for ADCs. |
In vitro | SGD-1882 is not an MDR1 substrate, and SGN-CD33A is conjugated to the SGD-1882. SGN-CD33A can kill MDR1 expressing CD33 positive AML patient samples and is currently in Phase I[2]. |
Synonyms | PBD dimer |
Molecular Weight | 725.79 |
Formula | C42H39N5O7 |
CAS No. | 1222490-34-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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SGD-1882 1222490-34-7 Others SGD 1882 SGD1882 PBD dimer inhibitor inhibit