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Cefotiam hydrochloride

Catalog No. T1616   CAS 66309-69-1
Synonyms: Pansporin, SCE-963 hydrochloride, Pansporine, Cefotiam dihydrochloride, Halospor

Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.

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Cefotiam hydrochloride Chemical Structure
Cefotiam hydrochloride, CAS 66309-69-1
Pack Size Availability Price/USD Quantity
10 mg In stock $ 39.00
50 mg In stock $ 55.00
100 mg In stock $ 80.00
200 mg In stock $ 118.00
500 mg In stock $ 198.00
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Purity: 98.74%
Purity: 98.23%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Cefotiam hydrochloride (SCE-963 hydrochloride) is the hydrochloride salt form of cefotiam, a third-generation, semi-synthetic, beta-lactam cephalosporin antibiotic with antibacterial activity. Cefotiam binds to penicillin-binding proteins (PBPs), transpeptidases that are responsible for crosslinking of peptidoglycan. By preventing crosslinking of peptidoglycan, cell wall integrity is lost and cell wall synthesis is halted.
Synonyms Pansporin, SCE-963 hydrochloride, Pansporine, Cefotiam dihydrochloride, Halospor
Molecular Weight 598.6
Formula C18H23N9O4S3.2HCl
CAS No. 66309-69-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 6.1 mg/mL (10.19 mM)

TargetMolReferences and Literature

1. Matsuda K, et al. Antimicrob Agents ChemOthers. 1995 Dec;39(12):2631-4.

Related compound libraries

This product is contained In the following compound libraries:
Drug Repurposing Compound Library Bioactive Compound Library ReFRAME Related Library Covalent Inhibitor Library Approved Drug Library Anti-COVID-19 Compound Library Anti-Bacterial Compound Library Beta-Lactam Compound Library Antibiotics Library NO PAINS Compound Library

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Keywords

Cefotiam hydrochloride 66309-69-1 Microbiology/Virology Antibacterial Antibiotic gram-positive bacterias cephalosporin antibiotic SCE963 Bacterial inhibit gram-negative bacterias SCE963 Hydrochloride Pansporin SCE-963 hydrochloride Inhibitor Cefotiam Cefotiam Dihydrochloride SCE-963 Hydrochloride Pansporine SCE-963 antibacterial activity SCE 963 Hydrochloride Cefotiam dihydrochloride SCE 963 Halospor Cefotiam Hydrochloride inhibitor

 

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