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Search Result

Search Results for " cereblon "

20

Compounds

Cat No. Product Name Synonyms Targets
T13721 Homo-PROTAC cereblon degrader 1 Others , Ligand for E3 Ligase
Homo-PROTAC cereblon degrader 1 is a highly potent and efficient cereblon (CRBN) degrader with only minimal effects on IKZF1 and IKZF3.
T7763 Thalidomide-4-OH Cereblon ligand 2,E3 ligase Ligand 2 Ligand for E3 Ligase
Thalidomide-4-OH (E3 ligase Ligand 2) (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used to recruit of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) is a linker to form PROTACs
T7753 Thalidomide-O-COOH Cereblon ligand 3,E3 ligase Ligand 3,TCE35031 Others , Ligand for E3 Ligase
Thalidomide-O-COOH (Cereblon ligand 3) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTACs.
T10765 Eragidomide CC-90009,Cereblon modulator 1 Apoptosis , Ligand for E3 Ligase , Molecular Glues
Eragidomide (CC-90009; Cereblon modulator 1) is a cereblon (CRBN) E3 ligase modulator. Eragidomide specifically binds to CRBN, thereby affecting the activity of the ubiquitin E3 ligase complex.
T17916 Pomalidomide-PEG4-C2-NH2 Cereblon Ligand-Linker Conjugates 8,E3 Ligase Ligand-Linker Conjugates 22 Others , Ligand for E3 Ligase
Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) is a synthesized E3 ligase ligand-linker conjugate incorporating the Pomalidomide-based cereblon ligand and 4-unit PEG linker.
T82745 Cereblon inhibitor 1
Cereblon inhibitor 1, an isoindoline derivative, serves as a modulator of the cereblon E3 ubiquitin ligase and shows promise for applications in cancer research.
T15189 Thalidomide-O-amido-C4-N3 E3 ligase Ligand-Linker Conjugates 18,Cereblon Ligand-Linker Conjugates 4 Others , Ligand for E3 Ligase
Thalidomide-O-amido-C4-N3 (Cereblon Ligand-Linker Conjugates 4) is an E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a linker.
T17325 Pomalidomide-PEG4-C-COOH Cereblon Ligand -Linker Conjugates 1,E3 Ligase Ligand-Linker Conjugates 1 Others , E3 Ligase Ligand-Linker Conjugate
Pomalidomide-PEG4-C-COOH (E3 Ligase Ligand-Linker Conjugates 1) is a synthesized E3 ligase ligand-linker conjugate that combines the Pomalidomide-based cereblon ligand and 4-unit PEG linker used in PROTAC technology.
T7759 Thalidomide-O-amido-C4-NH2 TFA E3 ligase Ligand-Linker Conjugates 19 TFA,Cereblon Ligand-Linker Conjugates 6 TFA E3 Ligase Ligand-Linker Conjugate
Thalidomide-O-amido-C4-NH2 TFA (E3 ligase Ligand-Linker Conjugates 19 TFA) is a synthesized E3 ligase ligand-linker conjugate.
T7758 Thalidomide-O-amido-PEG3-C2-NH2 TFA E3 ligase Ligand-Linker Conjugates 14 TFA,Cereblon Ligand-Linker Conjugates 3 (TFA) Others , E3 Ligase Ligand-Linker Conjugate , Ligand for E3 Ligase
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG3-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand a...
T7760 Thalidomide-O-amido-C3-NH2 TFA Cereblon Ligand-Linker Conjugates 16 TFA,E3 Ligase Ligand-Linker Conjugates 52 TFA E3 Ligase Ligand-Linker Conjugate , Ligand for E3 Ligase
Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-C3-NH2 TFA incorporates the Thalidomide based cereblon ligand and a linker...
T17918 Thalidomide-O-amido-PEG2-C2-NH2 TFA E3 Ligase Ligand-Linker Conjugates 24 TFA,Cereblon Ligand-Linker Conjugates 10 TFA Others , E3 Ligase Ligand-Linker Conjugate
Thalidomide-O-amido-PEG2-C2-NH2 TFA (E3 Ligase Ligand-Linker Conjugates 24 TFA) is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-PEG2-C2-NH2 TFA incorporates the Thalidomide based cereblon ligand a...
T17875 Pomalidomide-C2-NH2 Cereblon Ligand-Linker Conjugates 15,4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Others , Ligand for E3 Ligase
Pomalidomide-C2-NH2 (4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione) is a synthesized E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.
T17919 Thalidomide-O-amido-C6-NH2 TFA E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate,Cereblon Ligand-Linker Conjugates 11 TFA,E3 Ligase Ligand-Linker Conjugates 25 TFA Others , Ligand for E3 Ligase
Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based cereblon ligand and a linker.
T18063 Lenalidomide-acetylene-C5-COOH Cereblon ligand-linker Conjugate Others
Lenalidomide-acetylene-C5-COOH (compound 43; Cereblon ligand-linker Conjugate) serves as a Lenalidomide-based Cereblon ligand that facilitates the recruitment of the CRBN protein. This compound can be connected to the pr...
T7755 Thalidomide 4-fluoride E3 ligase Ligand 4 IRAK , Ligand for E3 Ligase
Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) ...
T17928 Lenalidomide-C5-NH2 E3 ligase Ligand-Linker Conjugates 31,Cereblon Ligand-Linker Conjugates 19 Others
Lenalidomide-C5-NH2 is the Lenalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Lenalidomide-C5-NH2 can be connected to the ligand for protein by a linker to form PROTACs[1].
T17878 Lenalidomide-C4-NH2 hydrochloride Cereblon ligand 1 hydrochloride,E3 ligase Ligand-Linker Conjugates 32 hydrochloride Others
Lenalidomide-C4-NH2 hydrochloride is a Cereblon ligand derived from Lenalidomide. It serves as a recruiting agent for the CRBN protein. The compound, known as PROTAC (Compound 24), can be formed by linking Lenalidomide-C...
T17904 Pomalidomide-PEG1-C2-N3 E3 ligase Ligand-Linker Conjugates 50,Cereblon Ligand-Linker Conjugates 13 Others
Pomalidomide-PEG1-C2-N3 is a compound that has been synthesized as a conjugate of an E3 ligase ligand-linker. This compound incorporates the cereblon ligand based on Pomalidomide and a 1-unit PEG linker, which are common...
T18555 Pomalidomide-PEG2-Tos Cereblon Ligand-Linker Conjugates 16,E3 ligase Ligand-Linker Conjugates 52 Others
Pomalidomide-PEG2-Tos is a compound that consists of an E3 ligase ligand-linker conjugate. It is composed of a cereblon ligand conjugated to a two-unit PEG linker[1].

Compounds

Homo-PROTAC cereblon degrader 1
T13721
Synonym:
Target: Others, Ligand for E3 Ligase
Thalidomide-4-OH
T7763
Synonym: Cereblon ligand 2,E3 ligase Ligand 2
Target: Ligand for E3 Ligase
Thalidomide-O-COOH
T7753
Synonym: Cereblon ligand 3,E3 ligase Ligand 3,TCE35031
Target: Others, Ligand for E3 Ligase
Eragidomide
T10765
Synonym: CC-90009,Cereblon modulator 1
Target: Apoptosis, Ligand for E3 Ligase, Molecular Glues
Pomalidomide-PEG4-C2-NH2
T17916
Synonym: Cereblon Ligand-Linker Conjugates 8,E3 Ligase Ligand-Linker Conjugates 22
Target: Others, Ligand for E3 Ligase
Cereblon inhibitor 1
T82745
Synonym:
Target:
Thalidomide-O-amido-C4-N3
T15189
Synonym: E3 ligase Ligand-Linker Conjugates 18,Cereblon Ligand-Linker Conjugates 4
Target: Others, Ligand for E3 Ligase
Pomalidomide-PEG4-C-COOH
T17325
Synonym: Cereblon Ligand -Linker Conjugates 1,E3 Ligase Ligand-Linker Conjugates 1
Target: Others, E3 Ligase Ligand-Linker Conjugate
Thalidomide-O-amido-C4-NH2 TFA
T7759
Synonym: E3 ligase Ligand-Linker Conjugates 19 TFA,Cereblon Ligand-Linker Conjugates 6 TFA
Target: E3 Ligase Ligand-Linker Conjugate
Thalidomide-O-amido-PEG3-C2-NH2 TFA
T7758
Synonym: E3 ligase Ligand-Linker Conjugates 14 TFA,Cereblon Ligand-Linker Conjugates 3 (TFA)
Target: Others, E3 Ligase Ligand-Linker Conjugate, Ligand for E3 Ligase
Thalidomide-O-amido-C3-NH2 TFA
T7760
Synonym: Cereblon Ligand-Linker Conjugates 16 TFA,E3 Ligase Ligand-Linker Conjugates 52 TFA
Target: E3 Ligase Ligand-Linker Conjugate, Ligand for E3 Ligase
Thalidomide-O-amido-PEG2-C2-NH2 TFA
T17918
Synonym: E3 Ligase Ligand-Linker Conjugates 24 TFA,Cereblon Ligand-Linker Conjugates 10 TFA
Target: Others, E3 Ligase Ligand-Linker Conjugate
Pomalidomide-C2-NH2
T17875
Synonym: Cereblon Ligand-Linker Conjugates 15,4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Target: Others, Ligand for E3 Ligase
Thalidomide-O-amido-C6-NH2 TFA
T17919
Synonym: E3 Ligase Ligand-Linker Conjugates 25 Trifluoroacetate,Cereblon Ligand-Linker Conjugates 11 TFA,E3 Ligase Ligand-Linker Conjugates 25 TFA
Target: Others, Ligand for E3 Ligase
Lenalidomide-acetylene-C5-COOH
T18063
Synonym: Cereblon ligand-linker Conjugate
Target: Others
Thalidomide 4-fluoride
T7755
Synonym: E3 ligase Ligand 4
Target: IRAK, Ligand for E3 Ligase
Lenalidomide-C5-NH2
T17928
Synonym: E3 ligase Ligand-Linker Conjugates 31,Cereblon Ligand-Linker Conjugates 19
Target: Others
Lenalidomide-C4-NH2 hydrochloride
T17878
Synonym: Cereblon ligand 1 hydrochloride,E3 ligase Ligand-Linker Conjugates 32 hydrochloride
Target: Others
Pomalidomide-PEG1-C2-N3
T17904
Synonym: E3 ligase Ligand-Linker Conjugates 50,Cereblon Ligand-Linker Conjugates 13
Target: Others
Pomalidomide-PEG2-Tos
T18555
Synonym: Cereblon Ligand-Linker Conjugates 16,E3 ligase Ligand-Linker Conjugates 52
Target: Others
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