Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Pomalidomide-PEG1-C2-N3 is a compound that has been synthesized as a conjugate of an E3 ligase ligand-linker. This compound incorporates the cereblon ligand based on Pomalidomide and a 1-unit PEG linker, which are commonly used in PROTAC technology. Utilizing Pomalidomide-PEG1-C2-N3, it is possible to design a selective CDK6 PROTAC degrader known as CP-10. CP-10 effectively induces the degradation of CDK6, displaying a DC50 value of 2.1 nM[1].
Pack Size | Availability | Price/USD | Quantity |
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2 mg | 5 days | $ 45.00 |
Description | Pomalidomide-PEG1-C2-N3 is a compound that has been synthesized as a conjugate of an E3 ligase ligand-linker. This compound incorporates the cereblon ligand based on Pomalidomide and a 1-unit PEG linker, which are commonly used in PROTAC technology. Utilizing Pomalidomide-PEG1-C2-N3, it is possible to design a selective CDK6 PROTAC degrader known as CP-10. CP-10 effectively induces the degradation of CDK6, displaying a DC50 value of 2.1 nM[1]. |
Synonyms | E3 ligase Ligand-Linker Conjugates 50, Cereblon Ligand-Linker Conjugates 13 |
Molecular Weight | 386.36 |
Formula | C17H18N6O5 |
CAS No. | 2271036-44-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Pomalidomide-PEG1-C2-N3 2271036-44-1 Others Pomalidomide-PEG-1-C2-N3 Pomalidomide PEG1 C2 N3 E3 ligase Ligand-Linker Conjugates 50 PomalidomidePEG1C2N3 Cereblon Ligand-Linker Conjugates 13 inhibitor inhibit