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Thalidomide 4-fluoride

Thalidomide 4-fluoride
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Purity:99.12%
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Thalidomide 4-fluoride

Catalog No. T7755Cas No. 835616-60-9
Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
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500 mg$29In Stock
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Product Introduction

Bioactivity
Description
Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment of CRBN protein. Thalidomide 4-fluoride (Cereblon ligand 4) can be connected to the ligand for IRAK4 protein by a linker to form PROTAC IRAK4 degrader-1.
AliasE3 ligase Ligand 4
Chemical Properties
Molecular Weight276.22
FormulaC13H9FN2O4
Cas No.835616-60-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 199 mg/mL (720.44 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.6203 mL18.1015 mL36.2030 mL181.0151 mL
5 mM0.7241 mL3.6203 mL7.2406 mL36.2030 mL
10 mM0.3620 mL1.8102 mL3.6203 mL18.1015 mL
20 mM0.1810 mL0.9051 mL1.8102 mL9.0508 mL
50 mM0.0724 mL0.3620 mL0.7241 mL3.6203 mL
100 mM0.0362 mL0.1810 mL0.3620 mL1.8102 mL

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