carcinomas — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4903	Heptadecanoic acid		Others , Endogenous Metabolite
	Heptadecanoic acid is a fatty acid of exogenous (primarily ruminant) origin. Many "odd" length long chain amino acids are derived from the consumption of dairy fats (milk and meat). Heptadecanoic acid constitutes 0.61% o...		Others , Endogenous Metabolite
T5469	K-Ras-IN-1		Raf , Ras
	K-Ras-IN-1 is a K-Ras inhibitor.		Raf , Ras
T6023	Nutlin-3a	(-)-Nutlin-3,Nutlin-3a chiral,(−)-Nutlin-3	Apoptosis , E1/E2/E3 Enzyme , Autophagy
	Nutlin-3a ((−)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits MDM2-p53 interactions and stabilizes the p53 protein.		Apoptosis , E1/E2/E3 Enzyme , Autophagy
TP1554L	HPV16 E7 (86-93) acetate	HPV16 E7 (86-93) acetate(160212-93-1 Free base)	Others
	HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas.		Others
T9007	Germinone A	3-Methyl-5-((3-nitro-[1,1'-biphenyl]-4-yl)oxy)furan-2(5H)-one	Others
	Germinone A (3-Methyl-5-((3-nitro-[1,1'-biphenyl]-4-yl)oxy)furan-2(5H)-one) is a novel potent agonist of HTL/KAI2, stimulating activity for Arabidopsis seed germination, has antitumor activity in multiple types of carcin...		Others
T33411	Mitopodozide	SP-I 77,SPI 77,SPI-77
	Mitopodozide, as an ethylhydrazide derivative of podophyllic acid, acts as a mitotic poison in carcinomas of the ovary.
T72355	KRAS G12D inhibitor 16
	KRAS G12D Inhibitor 16 is a potent compound targeting the KRAS G12D and its mutation, exhibiting inhibitory activity with IC50 values of 0.7 nM and 0.35 μM, respectively. It is utilized in researching various malignant t...
TP1427	ReACp53
	ReACp53 is a cell-penetrating peptide, designed to inhibit p53 amyloid formation, resues p53 function in cancer cell lines and in organoids derived from high-grade serous ovarian carcinomas (HGSOC).
T3425	Polyphyllin G	Polyphyllin VII,Polyphyllin VII,Y-0166	Others
	Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, cervical cancer, hepatocel...		Others
T76015	HPV16 E7 (86-93) (TFA)
	HPV16 E7 (86-93) TFA, a peptide derived from HPV16 E7, is restricted by human leukocyte antigen (HLA)-A2.1 and exhibits immunogenic properties in cervical carcinomas [1] [2].
T36415	N-Nitroso-N-methyl-4-Aminobutyric Acid
	N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) is a tobacco-specific nitrosamine carcinogen.1It is oxidized to the reactive metabolite methyl-2-oxopropylnitrosamine (MOPN) in isolated rat liver mitochondria.2NMBA induces ...
T72319	Lewis y tetrasaccharide	Lewis y
	Lewis Y Tetrasaccharide (Lewis Y, Le Y) is a tetrasaccharide derivative of Lewis X Trisaccharide, functioning as an antigen linked to the metastasis of malignant ovarian carcinomas and associated with a poor prognosis [1...
TN4113	Garcinone E		Antifection
	Garcinone E is active constituents in the anticomplement assay used. Garcinone E exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC50 values below 3 µM. It has potent...		Antifection
T78284	Edrecolomab	CO17-1A,Panorex
	Edrecolomab (Panorex), a murine monoclonal antibody targeting the 17-1A cell-surface glycoprotein on epithelial tissues and various carcinomas, exhibits anti-tumor properties and is utilized in colorectal carcinoma resea...
T63199	Dalpiciclib hydrochloride
	Dalpiciclib (SHR-6390) hydrochloride is a highly selective, orally active CDK4/6 inhibitor with IC50 values of 12.4 nM and 9.9 nM, respectively, and is capable of acting as an antitumor agent in breast and esophageal squ...
T20016	Diuron	HW 920,Dirurol,Karmex,Lucenit,Marmer,Seduron
	Diuron is a Phenylurea herbicide that inhibits photosynthesis by preventing the formation of ATP and NADH. Diuron (25 nM/ml) decreases total respiration in roots of wheat by 50% and ground respiration by 100%. Diuron (2,...
TP2005	Kisspeptin-54(human)	Metastin (human)
	Potent endogenous ligand of the kisspeptin receptor (KISS1, GPR54). Binds with high affinity to rat and human KISS1 receptors with Ki values of 1.80 and 1.45 nM respectively. Inhibits chemotaxis, invasion and metastasis ...
T79226	AMPK activator 11		Mitochondrial Metabolism
	AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-activated protein kinase (AMPK) and enhancement of oxidative...		Mitochondrial Metabolism
T76723	Tilvestamab
	Tilvestamab (BGB149), a humanized anti-AXL antibody, effectively blocks AXL-mediated cell signaling, significantly reduces Gas6-induced AXL activation, and inhibits downstream AKT phosphorylation in 786-0-Luc RCC cells. ...
T64475	FMOC-L-THR
	FMOC-L-THR (AZP-531) is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight. The O-glycosidic linkage and the O-acetyl protection in this building block is stable to both piperidine ...