bleeding — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T13920L	Terlipressin Acetate	Terlipressin diacetate anhydrous,Terlipressin acetate anhydrous	Vasopressin Receptor
	Terlipressin Acetate, a highly selective vasopressin V1 receptor agonist, on oxygen and glucose deprivation/re-oxygenation (OGD/R)-induced damage in intestinal epithelial cells (IEC-6).Terlipressin acetate exerts anti-in...		Vasopressin Receptor
T6991	Nitroprusside disodium dihydrate	Sodium Nitroferricyanide(III) Dihydrate,Sodium Nitroprusside Dihydrate	Guanylate cyclase , Autophagy
	Nitroprusside disodium dihydrate (Sodium Nitroprusside Dihydrate) is a potent vasodilator working through releasing NO spontaneously in blood.		Guanylate cyclase , Autophagy
T0881	6-Aminocaproic acid	EACA,6-Aminohexanoic acid,Epsilon-Amino-n-caproic Acid,(6-)ε-Aminocaproic acid	Others
	6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.		Others
T11918	Lysipressin	Lysine vasopressin,[Lys8]-Vasopressin	Others
	Lysipressin ([Lys8]-Vasopressin), Induces contraction of the rabbit urinary bladder smooth muscle, activate adenylate-cyclase. Lysipressin is Antidiuretic hormone that have been found in pigs and some marsupial families.		Others
T13693	Fibrin		Others
	Fibrin, the primary constituent of blood clots, is an insoluble protein essential for coagulation. Isolated from bovine blood, this protein is notably synthesized in response to bleeding.		Others
T14865	Carboprost tromethamine		Prostaglandin Receptor
	Carboprost tromethamine, a synthetic 15-methyl analogue of prostaglandin F2α, effectively promotes uterine contractions and significantly reduces bleeding during and post-delivery.		Prostaglandin Receptor
T7601L	Carbetocin acetate	Carbetocin acetate(37025-55-1 free base)	Oxytocin Receptor
	Carbetocin acetate is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth.		Oxytocin Receptor
TN7238L	Sanguinarine citrate	Sanguinarium citrate,Sanguinarin citrate,Pseudochelerythrine citrate	Antibiotic
	Sanguinarine citrate (Pseudochelerythrine chloride) is an alkaloid derived from Sanguinaria Canadensis with antimicrobial, anti-inflammatory, and analgesic activity that is used in the treatment of oral inflammatory dise...		Antibiotic
T1514	Norethindrone	Norethisterone	Estrogen/progestogen Receptor , Progesterone Receptor
	Norethindrone (Norethisterone) is a synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties...		Estrogen/progestogen Receptor , Progesterone Receptor
T11824LL	Lanraplenib	GS-9876	Syk
	Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib inhibits SYK activity in platelets via the glycoprotein VI ...		Syk
T3536	AZD1283		P2Y Receptor
	AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithromboti...		P2Y Receptor
T70349	DJT06001
	DJT06001 is a selective Factor Xa inhibitor, reducing thrombus formation with low risk of bleeding.
T28237	Onapristone	IVV-1001,ZK 98299,IVV 1001,ZK98299,ZK-98299,IVV1001
	Onapristone, a progesterone receptor antagonist, is used potentially for the treatment of breast cancer, advanced prostate cancer, and inducer of vaginal bleeding.
T20855	Gemeprost	SC-37681,SC 37681,Carprost,Gemeprostum,Cervagem,Preglandin
	Gemeprost, an analog of prostaglandin E1, is used for the treatment of obstetric bleeding. It is used to terminate pregnancy up to 24 weeks gestation together with mifepristone.
T11824	Lanraplenib succinate	GS-9876 succinate	Syk
	Lanraplenib succinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib succinate is a highly selective and orally active S...		Syk
T16377	Odiparcil	SB-424323	Thrombin
	Odiparcil is an orally active beta-d-thioxyloside analog. Odiparcil is an indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II). It also has an antit...		Thrombin
T11824L	Lanraplenib monosuccinate	GS-9876 monosuccinate	Syk
	Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans. Lanraplenib monosuccinate is a highly selective and orally...		Syk
T36178	Aspalatone
	Aspalatone is an anti-platelet aggregator (IC50 = 180 μM, in vitro) that prolongs bleeding time significantly in a rodent model of thromboembolism. Additionally at a minimal effective dose of 24 mg/kg, aspalatone generat...
T28491	R-1663	R1663
	R-1663 is a factor Xa inhibitor. R-1663 prolonged clotting times, inhibited thrombin generation (peak height and endogenous thrombin potential [ETP]) and anti-factor Xa activity in a concentration-dependent manner withou...
T68681	Casuarinin
	Casuarinin is an ellagitannin. It is found in the pericarp of pomegranates. It is also found in Casuarina and Stachyurus species and in Alnus sieboldiana. It is an isomer of casuarictin. It is a highly active carbonic a...