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Search Results for " bisphosphonate "

20

Compounds

Cat No. Product Name Synonyms Targets
T12452 Digeranyl bisphosphonate DGBP Rho , Ras
Digeranyl bisphosphonate (DGBP) is a potent geranylgeranyl pyrophosphate (GGPP) synthase inhibitor that inhibits geranyl pyrophosphorylation of Rac1.Digeranyl bisphosphonate induces autophagy but not apoptosis.
T69443 Aminobutane bisphosphonate
Aminobutane bisphosphonate is a powerful inhibitor of bone resorption. It can potentially be a useful measure for controlling hypercalcemia in patients with carcinoma.
T6739 Zoledronic Acid CGP-4244,CGP42446A,Zoledronate,CGP 42446,ZOL 446,Zometa Apoptosis , Rho , Autophagy
Zoledronic Acid (ZOL 446) is a bisphosphonate. Zoledronic Acid (ZOL 446) is used to prevent skeletal fractures in patients with cancers such as multiple myeloma and prostate cancer. It can also be used to treat hypercalc...
T21299 Zoledronic acid monohydrate zoledronate,ZOL 446,CGP 42446,CGP42446A,Zoledronic acid hydrate Apoptosis , Others , Autophagy
Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.
T1599 Ibandronic acid Bonviva,Bondronat,Boniva Others , HBV
Ibandronic acid (Bonviva) is a third-generation amino-bisphosphonate with anti-resorptive and anti-hypercalcemic activities.
T1337 Pamidronate Disodium CGP 23339A,CGP 23339AE,Pamidronate disodium salt Others , HBV
Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.
T1599L Ibandronate sodium Boniva,Ibandronate sodium salt,Bondronat HBV , Transferase
Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
T6539 Ibandronate sodium monohydrate Boniva monohydrate,Bondronat monohydrate,Ibandronate sodium,BM-210955,BM-21.0955,RPR-102289A Apoptosis , Others
Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
T73506 TH-Z93 THZ93 Antibacterial
TH-Z93 is a potent FPPS inhibitor (IC50:90 nM) and a lipophilic bisphosphonate.
T6373 Alendronate sodium hydrate G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,G-704650 Adronat,Fosamax Transferase
Alendronate sodium hydrate (MK 217) is a nitrogen-containing bisphosphonate, which is an effective inhibitor of bone resorption. It is utilized for the treatment and prevention of osteoporosis.
T16289 NE 10790 3-PEHPC Others
NE 10790 (3-PEHPC) is a phosphonocarboxylate analogue of the potent bisphosphonate risedronate and is a weak anti-resorptive agent. Although NE10790 was a poor inhibitor of FPP synthase
T6451 Clodronic acid disodium salt Loron,Clodronate Disodium,Lodronate Others
Clodronic acid disodium salt (Lodronate), a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.
T19415 Medronic acid Methylenediphosphonic acid Others
Medronic acid (Methylenediphosphonic acid), a methylene-substituted bisphosphonate, exhibits affinity for and adherence to hydroxyapatite crystals within the bone matrix. Accumulating at sites of osteoid mineralization, ...
T14766 BPH-715 Others , Parasite
BPH-715 inhibits the liver-stage growth of P. falciparum with an IC50 of 10 μM for P. falciparum exoerythrocytic forms in HepG2 cells.
T10586L BPH-1358 NSC50460 Others , Antibacterial
BPH-1358 (NSC-50460) (NSC-50460) is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. With IC50s of 1.8 μM and 110 nM, respectively. And it is active against S. a...
T26928 BV600022 BV-600022,BV 600022
BV600022 is an osteoadsorptive bisphosphonate-ciprofloxacin conjugate with antibacterial activity.
T33873 Pamidronate monosodium Pamidronic acid monosodium salt,J710.127I,Pamidronate-monosodium
Pamidronate monosodium is a bisphosphonate.
T30836 Cgp 47072 Cgp-47072,Cgp47072
Cgp 47072 is a bisphosphonate, used in the treatment of bone diseases, particularly where there is uncontrolled bone resorption.
T28151 NE21650 NE-21650,NE 21650
NE21650, a bisphosphonate, inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase.
T11956L MBC-11 Others
MBC-11 is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC). It also has the potential to treat tumor-induced bone disease (TIBD).

Compounds

Digeranyl bisphosphonate
T12452
Synonym: DGBP
Target: Rho, Ras
Aminobutane bisphosphonate
T69443
Synonym:
Target:
Zoledronic Acid
T6739
Synonym: CGP-4244,CGP42446A,Zoledronate,CGP 42446,ZOL 446,Zometa
Target: Apoptosis, Rho, Autophagy
Zoledronic acid monohydrate
T21299
Synonym: zoledronate,ZOL 446,CGP 42446,CGP42446A,Zoledronic acid hydrate
Target: Apoptosis, Others, Autophagy
Ibandronic acid
T1599
Synonym: Bonviva,Bondronat,Boniva
Target: Others, HBV
Pamidronate Disodium
T1337
Synonym: CGP 23339A,CGP 23339AE,Pamidronate disodium salt
Target: Others, HBV
Ibandronate sodium
T1599L
Synonym: Boniva,Ibandronate sodium salt,Bondronat
Target: HBV, Transferase
Ibandronate sodium monohydrate
T6539
Synonym: Boniva monohydrate,Bondronat monohydrate,Ibandronate sodium,BM-210955,BM-21.0955,RPR-102289A
Target: Apoptosis, Others
TH-Z93
T73506
Synonym: THZ93
Target: Antibacterial
Alendronate sodium hydrate
T6373
Synonym: G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,G-704650 Adronat,Fosamax
Target: Transferase
NE 10790
T16289
Synonym: 3-PEHPC
Target: Others
Clodronic acid disodium salt
T6451
Synonym: Loron,Clodronate Disodium,Lodronate
Target: Others
Medronic acid
T19415
Synonym: Methylenediphosphonic acid
Target: Others
BPH-715
T14766
Synonym:
Target: Others, Parasite
BPH-1358
T10586L
Synonym: NSC50460
Target: Others, Antibacterial
BV600022
T26928
Synonym: BV-600022,BV 600022
Target:
Pamidronate monosodium
T33873
Synonym: Pamidronic acid monosodium salt,J710.127I,Pamidronate-monosodium
Target:
Cgp 47072
T30836
Synonym: Cgp-47072,Cgp47072
Target:
NE21650
T28151
Synonym: NE-21650,NE 21650
Target:
MBC-11
T11956L
Synonym:
Target: Others
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TargetMol