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Zoledronic acid monohydrate

Catalog No. T21299 CAS 165800-06-6

Synonyms: zoledronate, ZOL 446, CGP 42446, CGP42446A, Zoledronic acid hydrate

Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.

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Zoledronic acid monohydrate Chemical Structure

Zoledronic acid monohydrate, CAS 165800-06-6

Pack Size	Availability	Price/USD
10 mg	In stock	$ 34.00
25 mg	In stock	$ 53.00
50 mg	In stock	$ 77.00
100 mg	In stock	$ 127.00
200 mg	In stock	$ 188.00
500 mg	In stock	$ 293.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.

Synonyms	zoledronate, ZOL 446, CGP 42446, CGP42446A, Zoledronic acid hydrate
Molecular Weight	290.1
Formula	C5H12N2O8P2
CAS No.	165800-06-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: Insoluble

References and Literature

1. Albani-Campanario M , G Buendía-Díaz, Flores-Islas M , et al. [Zoledronic acid-based uveitis: a case report and a bibliography review][J]. Ginecología Y Obstetricia De México, 2012, 80(5):355-9. 2. Huang WW, Huang C, Liu J, Zheng HY, Lin L. Zoledronic acid as an adjuvant therapy in patients with breast cancer: a systematic review and meta-analysis. PLoS One. 2012;7(7):e4078doi: 10.1371/journal.pone.004078Epub 2012 Jul 26. Review. PubMed PMID: 22844410; PubMed Central PMCID: PMC3406041. 3. Zhang J, Wang R, Zhao YL, Sun XH, Zhao HX, Tan L, Chen DC, Hai-Bin X. Efficacy of intravenous zoledronic acid in the prevention and treatment of osteoporosis: a meta-analysis. Asian Pac J Trop Med. 2012 Sep;5(9):743-8. doi: 10.1016/S1995-7645(12)60118-7. Review. PubMed PMID: 22805729. 4. Hadji P, Coleman R, Gnant M, Green J. The impact of menopause on bone, zoledronic acid, and implications for breast cancer growth and metastasis. Ann Oncol. 2012 Nov;23(11):2782-90. doi: 10.1093/annonc/mds169. Epub 2012 Jun 2Review. PubMed PMID: 22730099; PubMed Central PMCID: PMC3477882.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Active Compound Library Anti-Cancer Drug Library EMA Approved Drug Library Anti-Cancer Approved Drug Library Drug Repurposing Compound Library Approved Drug Library Autophagy Compound Library NO PAINS Compound Library Apoptosis Compound Library Hematonosis Compound Library

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Zoledronic acid monohydrate 165800-06-6 Apoptosis Autophagy Others osteoclast inhibit bisphosphonate osteoporosis ZOL446 CGP42446 Zoledronic acid zoledronate CGP-42446 anti-resorptive activity ZOL 446 anti-cancer ZOL-446 Zoledronic acid Monohydrate CGP 42446 Zoledronic acid Hydrate CGP42446A Inhibitor Zoledronic acid hydrate inhibitor

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