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Ibandronate sodium
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Catalog No. T1599LCas No. 138844-81-2
Alias Ibandronate sodium salt, Boniva, Bondronat
Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
Ibandronate sodium
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Purity: 98.13%
Catalog No. T1599LAlias Ibandronate sodium salt, Boniva, BondronatCas No. 138844-81-2
Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 mg | $40 | In Stock | In Stock | |
| 500 mg | $92 | - | In Stock | |
| 1 g | $133 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.13%
Appearance:Solid
Color:White
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Product Introduction
Ibandronate sodium AI Summary
Ibandronate sodium has been tested in various assays to determine its antiviral activity. Notably, it has demonstrated bioactivity in inhibiting the entry of the Ebola virus, with AC50 values ranging from 281.8 nM to 11.22 μM across different screening channels, indicating its potential as an antiviral agent at the entry stage of the Ebola virus. In contrast, this compound exhibits a very low inhibition index of 0.004194 for cell viability in Vero E6 cells infected with SARS-CoV-2, suggesting negligible activity against this virus. Additionally, Ibandronate sodium showed inhibition of less than 5.0% on the Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells at a concentration of 100 μM, determined using an FRET-based assay, further emphasizing its limited effect in this context..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis. |
| Synonyms | Ibandronate sodium salt, Boniva, Bondronat |
| Molecular Weight | 341.21 |
| Formula | C9H22NNaO7P2 |
| Cas No. | 138844-81-2 |
| Smiles | O.[Na+].CCCCCN(C)CCC(O)(P(O)(O)=O)P(O)([O-])=O |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: Insoluble H2O: 10 mM, Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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