biofilm — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TN1545	D-Tyrosine		Tyrosinase
	D-Tyrosine, the D-isomer of tyrosine, acts as a negative regulator of melanin synthesis by inhibiting tyrosinase activity. Furthermore, D-Tyrosine also inhibits biofilm formation and induces the self-dispersal of biofilm...		Tyrosinase
T36735	3,5-Di-tert-butylphenol		Reactive Oxygen Species , Antifungal
	3,5-Di-tert-butylphenol induces accumulation of reactive oxygen species. 3,5-Di-tert-butylphenol exhibits anti-biofilm and antifungal activities.		Reactive Oxygen Species , Antifungal
T8507	MAC-545496		Antibacterial
	MAC-545496 is a glycopeptide-resistance-associated protein R (GraR) inhibitor, is an antivirulence agent.		Antibacterial
T1305	Ceftazidime	GR20263	Antibacterial , Antibiotic
	Ceftazidime (GR20263) is a beta-lactam, cephalosporin antibiotic with bactericidal activity.		Antibacterial , Antibiotic
T3S2340	Usaramine	(15E)-Retrorsine,Mucronatine,NISTC15503874	Others , Antibacterial
	Usaramine (Mucronatine) demonstrates phytotoxicity against Lactuca sativa var. Carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr.		Others , Antibacterial
T3S1319	(+)-Magnoflorine	Escholin,Magnoflorine,Thalictrin,Escholine	Others , Antifungal
	(+)-Magnoflorine (Thalictrin) has sedative and anxiolytic effects, probably mediated by Magnoflorine through a GABAergic mechanism of action. Magnoflorine and Sinomenine have protective effects, are mediated by some mech...		Others , Antifungal
T3S1320	(+)-Magnoflorine iodide	Magnoflorine iodide,Thalictrine iodide,Corytuberine Methiodide	Others , Antifungal
	(+)-Magnoflorine iodide (Thalictrine iodide) has anti-inflammatory activity, it can inhibit inflammations.		Others , Antifungal
T4S1321	(+)-Magnoflorine chloride	Magnoflorine chloride,Corytuberine methochloride,Thalictrine chloride,Escholine chloride	Others , Antifungal
	(+)-Magnoflorine chloride (Escholine chloride) has anti-inflammatory activity, it can inhibit inflammations.		Others , Antifungal
T18408	N-Butanoyl-L-homoserine lactone	N-Butyryl-L-homoserine lactone,C4-HSL	Antibacterial
	N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm...		Antibacterial
TQ0251	(Z)-2-decenoic acid	(Z)-dec-2-enoic acid,cis-2-Decenoic acid,cis-dec-2-enoic acid	Others
	(Z)-2-decenoic acid (cis-dec-2-enoic acid) is an unsaturated short-chain fatty acid secreted by Pseudomonas aeruginosa. It can induce a dispersion response in biofilms formed by gram-negative and gram-positive bacteria. ...		Others
T8261	Ceftazidime Pentahydrate		Antibacterial , Antibiotic
	Ceftazidime is a β-lactam antibacterial agent which has demonstrated a broad spectrum of activity against Gram-positive and Gram-negative aerobic bacteria.		Antibacterial , Antibiotic
T83096	Antibiofilm agent-2
	Antibiofilm Agent-2 (Compound 4T) serves as a potent biofilm inhibitor, exhibiting an IC50 of 3.6 μM, and impairs the quorum sensing system along with iron homeostasis, acting as antibacterial synergists against Pseudomo...
T12094	Monobehenin		Others , Antibacterial
	Monobehenin has a strong inhibitory effect on the formation of bacterial biofilm.		Others , Antibacterial
T15254	Ethyl acetoacetate	Ethyl acetylacetate	Others , Antibacterial
	Ethyl acetoacetate (Ethyl acetylacetate) is a bacterial biofilm inhibitor.Ethyl acetoacetate is an ester, an intermediate that can be used in the synthesis of many compounds.		Others , Antibacterial
T5S0636	Citric acid	Citro,Citretten	Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
	1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
T13947	Tween 80		Others
	Tween 80 is a nonionic surfactant and emulsifier that reduces bacterial adherence and inhibits biofilm formation. Tween 80 is widely used as a co-solvent in pharmacology experiments because of its ability to enhance the ...		Others
T67731	Holomycin	N-Demethylthiolutin	DNA/RNA Synthesis
	Holomycin (N-Demethylthiolutin) is a secondary metabolite of dithiopyrrolidone. HolomycinHolomycin, an antibiotic secondary metabolite, is required for the biofilm formation of natural photogenic Bacillus galatheae S2753...		DNA/RNA Synthesis
T35805	C16 Sphingomyelin (d18:1/16:0)	Sphingomyelin 16:0,N-Palmitoyl-D-sphingomyelin	Endogenous Metabolite
	C16 Sphingomyelin (d18:1/16:0) (N-Palmitoyl-D-sphingomyelin) is a phospholipid analog of phospholipid bilayer membranes, which can be used to study biofilm activity.		Endogenous Metabolite
T6S2116	Ginkgolic acid C17:1		Phosphatase , PTEN
	1. Ginkgolic acid C17:1 can significantly inhibit enterohemorrhagic Escherichia coli O157:H7(EHEC) biofilm formation on the surfaces of polystyrene and glass, and on nylon membranes.		Phosphatase , PTEN
TN1925	Methyl anthranilate		Others , Antibacterial
	Methyl anthranilate is a natural product. Methyl anthranilate is a novel quorum sensing inhibitor and anti-biofilm agent against Aeromonas sobria		Others , Antibacterial