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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T78955 | Analgesic agent-2 | Sodium Channel | |
Analgesic Agent-2, a selective orally active inhibitor of the NaV1.8 channel, demonstrates an IC50 of 50.18 nM in HEK293 cells that stably express the human NaV1.8 channel, indicating its potential for analgesic activity... | |||
T62195 | Analgesic agent-1 | ||
Analgesic agent-1 is a potent analgesic that exhibits significant analgesic activity. | |||
T2553 | Etofenamate | COX | |
Etofenamate is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain. | |||
T3S0509 | Gaultherin | COX | |
Gaultherin has analgesic, and anti-inflammatory activities.Gaultherin lacks gastric ulcerogenic effect, because of it released salicylate in intestine slowly, not in stomach and it left the cyclooxygenase-1 unaffected, w... | |||
T7930 | Linalyl Acetate | Others | |
Linalyl Acetate is a natural product | |||
T6S1435 | Notopterol | Apoptosis , Others | |
1. Notopterol induces apoptosis and inhibits cell cycle-specific. | |||
T8206 | Cycleanine | Others | |
Cycleanine has potent antibacterial, antifungal, antiplasmodial, and cytotoxic activities. | |||
T5424 | Etosalamide | Ethosalamide | Others |
Etosalamide (Ethosalamide) is an antipyretic and analgesics agent. | |||
T40377 | Nicotredole | Tryptamide | Others |
Nicotredole (Tryptamide) (Tryptamide) is an orally active analgesic and anti-inflammatory agent. Nicotredole exhibits evident anti-inflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak... | |||
T0734 | Antipyrine | Phenazone,Phenazon | COX |
Antipyrine (Phenazone), an antipyretic and analgesic, has been given as ear drops and by mouth. Antipyrine is frequently used to test the effects of other diseases or drugs on drug-metabolizing enzymes in the liver. | |||
T4S1943 | Kirenol | Kirel | Wnt/beta-catenin |
1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid... | |||
TN1712 | Gossypin | NF-κB , S6 Kinase | |
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role i... | |||
T0778 | Phenacetin | Acetophenetidin | COX |
Phenacetin (Acetophenetidin) is a phenylacetamide that was formerly used in ANALGESICS but nephropathy and METHEMOGLOBINEMIA led to its withdrawal from the market. | |||
T0044 | Oxethazaine | Oxetacaine | HBV , Sodium Channel |
Oxethazaine (Oxetacaine), a topical anesthetic, is used to prevent acid-induced esophageal pain. | |||
T5460 | Mofezolac | COX | |
Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000 | |||
T1787 | Levobupivacaine | Sodium Channel | |
Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide. It is the S-enantiomer of bupivacaine. Levobupivacaine hydrochloride is commonly marketed by AstraZ... | |||
T4542 | Clonixin | Clonixic acid | Others |
Clonixin (Clonixic acid) is a non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. This compound has been reported to block prostaglandin synthesis, and to block inward calcium currents. | |||
T10152 | 4-Methylamino antipyrine | COX , Drug Metabolite | |
4-Methylamino antipyrine is an active metabolite of Metamizole. Metamizole is a pyrazolone non-steroidal anti-inflammatory drug (NSAID) and inhibits COX. 4-Methylamino antipyrine has analgesic, antipyretic, and relativel... | |||
T22360 | MDR-652 | TRP/TRPV Channel | |
MDR-652 is a highly specific and efficacious agonist of nonpungent transient receptor potential vanilloid 1 (TRPV1) with Ki value of 11.4 nM and 23.8 nM for hTRPV1 and rTRPV1 respectively and EC50s for hTRPV1 and rTRPV1 ... | |||
T40045 | Sivopixant | S-600918,Sivopixant | P2X Receptor |
Sivopixant (S-600918) (S-600918) is a potent and selective antagonist of P2X3 receptor (P2X3 IC 50 =4.2 nM; P2X2/3 IC 50 =1100 nM). Sivopixant shows strong analgesic effect . |