transaminase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8765	IGOT1-01		Others
	iGOT1-01 is an effective inhibitor of glutamate oxaloacetate transaminase 1(GOT1) . iGOT1-01 has IC50s of 84.6 μM and 11.3 μM in GOT1/MDH1 assay and GOT1/GLOX/HRP assay, respectively. iGOT1-01 can be used in anti-cancer ...		Others
T8766	GOT1 inhibitor-1	GOT1 inhibitor 2c	Others
	GOT1 inhibitor-1 (GOT1 inhibitor 2c) is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.		Others
T0128L	Vigabatrin Hydrochloride	γ-Vinyl-GABA hydrochloride	GABA Receptor
	Vigabatrin Hydrochloride (γ-Vinyl-GABA hydrochloride) is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA), which irreversibly inhibits the catabolism of GABA by GABA transaminase.		GABA Receptor
T40659L	γ-Acetylenic GABA hydrochloride	γ-Acetylenic GABA hydrochloride(57659-38-8 Free base)	Transaminase , GABA Receptor
	γ-Acetylenic GABA hydrochloride is a GABA transaminase inhibitor.		Transaminase , GABA Receptor
T7595	L-DABA	L-2,4-Diaminobutyric acid,L-DAB HBR	GABA Receptor , Endogenous Metabolite
	L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase (IC50 > 500 μM).		GABA Receptor , Endogenous Metabolite
T6S1918	Schisantherin B	Gomisin-B,Wuweizi ester-B,Schizantherin-B	Beta Amyloid , Others
	1. Schisantherin B (Schizantherin-B) shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.		Beta Amyloid , Others
T67927	BAY-069		Reactive Oxygen Species
	BAY-069 is an inhibitor. BAY-069 inhibited branched-chain amino acid transaminase 1 (BCAT1) at IC50:31 nM and branched-chain amino acid transaminase 2 (BCAT2) at IC50:153 nM. BAY-069 is a novel (trifluoromethyl) pyrimidi...		Reactive Oxygen Species
T2S1814	P-Hydroxybenzaldehyde	4-Formylphenol,4-hydroxybenzaldehyde,p-Oxybenzaldehyde	Transaminase , GABA Receptor , Endogenous Metabolite
	1. p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, and its inhibitory activity was higher than that of valproic...		Transaminase , GABA Receptor , Endogenous Metabolite
T3273	Bifendate	Bifendatatum	HBV , Reverse Transcriptase
	Bifendate (Bifendatatum) is commonly used to treat the transaminase elevation that caused by viral hepatitis and drug-induced liver injury.		HBV , Reverse Transcriptase
T77795	L-DABA hydrobromide	L-2,4-Diaminobutyric acid hydrobromide	Others , Endogenous Metabolite
	L-DABA hydrobromide (L-2,4-Diaminobutyric acid hydrobromide) is a potent GABA transaminase inhibitor with antitumor and anticonvulsant activity for the study of neurological disorders.		Others , Endogenous Metabolite
T0128	Vigabatrin	Sabril,Vigabatrine	GABA Receptor , ABC
	Vigabatrin (Sabril), an analogue of gamma-aminobutyric acid, is an irreversible inhibitor of 4-aminobutyrate Transaminase responsible for the catabolism of γ-aminobutyric acid.		GABA Receptor , ABC
T6474	Divalproex Sodium	Valproate semisodium,Epival	HDAC
	Divalproex Sodium (Valproate semisodium) binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzyme...		HDAC
TN2185	Schisantherin C		Others
	Schisantherin A, B, C, and D show good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.		Others
T24080	Gabaculine HCl	708-B,Gabaculine hydrochlorlide
	Gabaculine is an irreversible inhibitor of GABA transaminase (GABA-T; Ki: 2.9 μM). Gabaculine alters plastid development and differentially affects the abundance of plastid-encoded DPOR and nuclear-encoded GluTR.
T7622L	Gabazine free base	Chebi:34968,SR95531,C13796,J331.170H,SR 95531
	Gabazine free base is a specific antagonist of the GABA receptor. It does not affect GABA-transaminase or glutamate-decarboxylase activities.
T76364	Ac-Leu-Leu-Norleucinol
	Ac-Leu-Leu-Norleucinol (ALLN), a calpain inhibitor, is employed in the research of Acetaminophen-induced acute liver damage. It effectively reduces levels of glutamic-oxalacetic transaminase (ALT) and glutamic-pyruvic tr...
T40659	γ-Acetylenic GABA	4-Aminohex-5-ynoic acid,γ-Acetylenic GABA
	γ-Acetylenic GABA (4-Aminohex-5-ynoic acid) is a potent, irreversible inhibitor of GABA-transaminase. This compound effectively raises the concentration of γ-Aminobutyric acid (GABA) in the brain of rats.
T69068	Aspulvinone H
	Aspulvinone H is a natural inhibitor of glutamic oxaloacetate transaminase 1 (GOT1), suppressing glutamine metabolism, making PDAC cells sensitive to oxidative stress and inhibiting cell proliferation, exhibiting potent ...
TN2181	Sarmentosin		Others
	Sarmentosin significantly lowers the SGPT level of patients suffering from chronic viral hepatitis, and shows a suppressive effect on cell-mediated immune responses in mice. It shows a good effect in lowering serum gluta...		Others
T71305	Clofibric Acid-d4
	Clofibric acid-d4 is intended for use as an internal standard for the quantification of clofibric acid by GC- or LC-MS. Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 µM in a ...