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Search Results for " txb2 "

13

Compounds

Cat No. Product Name Synonyms Targets
T1867 Otenaproxesul ATB 346 Apoptosis , COX
Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.
T36683 Vedaprofen Quadrisol,PM 150,CERM 10202 COX , Antibacterial , Prostaglandin Receptor
Vedaprofen (PM 150) inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli sliding clamp with the IC50 of 222 μM and Ki of 131 μM.
T17191 Bunaprolast U66858 Lipoxygenase , LTR
Bunaprolast (U66858) is a novel and potent leukotriene B4 (LTB4) inhibitor.Bunaprolast exhibits oxidative degradation activity and inhibits lipoxygenase and TXB2 release.
T67959 Pirodomast Thrombin , Serine Protease
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospas...
T13144 Thiazinamium chloride Multergan chloride Others
Thiazinamium chloride possesses potent anticholinergic and antiallergic activity and inhibits synthesis of TxB2(IC50 value of 0.2 µM).
T11755 KF 13218 Histone Demethylase
KF 13218 is a selective, potent and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM.
T7053 P-Hydroxycinnamic acid p-Coumaric acid,p-Cumaric acid,p-Hydroxy-cinnamic acid,NSC 59260 Thrombin , Endogenous Metabolite , Prostaglandin Receptor
p-Hydroxycinnamic acid (NSC-59260) can inhibit platelet activity, with IC50s of 371 μM, 126 μM for thromboxane B2 production and lipopolysaccharide-induced prostaglandin E2 generation, respectively.
T10054 CI-949 Others
CI-949 is an allergic mediator release inhibitor, which inhibits leukotriene C4/D4 (LTC4/LTD4), histamine, and thromboxane B2 (TXB2) release (IC50s: 0.5 μM, 11.4 μM and 0.1 μM).
T36220 2,3-dinor Thromboxane B1 2,3-dinor Thromboxane B1
Thromboxane B2 (TXB2) is released in substantial quantities from aggregating platelets and metabolized during circulation to 11-dehydro TXB2 and 2,3-dinor TXB2. In rats and rabbits, 2,3-dinor TXB1 has been identified as ...
TN5939 Glutinone 5-Glutinen-3-one
Glutinone (IC50=24 microM) shows a significant effect on thromboxane B2 (TXB2)-release induced by calcium ionophore in human platelets.
T37300 PCTR1 PCTR1
Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by ...
T83662 2,3-dinor-8-iso Prostaglandin F1α 2,3-dinor-8-iso PGF1α,2,3-dinor-iPF1α-III,2,3-dinor-5,6-dihydro-15-F2t-Isoprostane,2,3-dinor-5,6-dihydro-15-F2t-IsoP
2,3-Dinor-8-iso Prostaglandin F1α (2,3-dinor-8-iso PGF1α), an isoprostane and active metabolite of arachidonic acid deriving its formation from non-enzymatic free radical peroxidation, acts as an active metabolite of the...
T37507 MCTR3 MCTR3
Maresin conjugates in tissue regeneration 3 (MCTR3) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages. DHA is oxidized to maresin 1 , which is converted to MCTR1 by glutat...
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