tace — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2569	Chlorotrianisene	tris(p-methoxyphenyl)chloroethylene,CTA,tri-p-anisylchloroethylene,TACE	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , COX
	Chlorotrianisene (tri-p-anisylchloroethylene) is an orally bioavailable, highly lipophilic, synthetic triphenylethylene (TPE) derivative and selective estrogen receptor modulator (SERM), with predominantly estrogenic but...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor , COX
T8961	GW280264X	Carbamic acid	MMP
	GW280264X (Carbamic acid) is an inhibitor of ADAM17 .		MMP
TP1413L	Crustacean Cardioactive Peptide Acetate	CCAP acetate
	Crustacean Cardioactive Peptide Acetate (CCAP acetate) is is the most conserved and ubiquitous neuropeptide in arthropods and is produced in insects by a network of conserved neurons in the ventral nerve cord.Crustacean ...
T0914	Metacetamol	3-Acetamidophenol	Others
	Metacetamol (3-Acetamidophenol) is a derivative of acetaminophen, a non-toxic regional isomer of acetaminophen. It is an over-the-counter analgesic and antipyretic and is also used as an organic synthesis intermediate.		Others
T1888	Tacedinaline	Acetyldinaline,N-acetyldinaline,PD-123654,CI994,Goe-5549	Apoptosis , HDAC
	Tacedinaline (CI994) is a selective class I HDAC inhibitor with potential antineoplastic activity.		Apoptosis , HDAC
TP1413	Crustacean Cardioactive Peptide (CCAP)	Crustacean Cardioactive Peptide CCAP
	Crustacean cardioactive peptide (CCAP) is a highly conserved, amidated cyclic nonapeptide with the primary structure PFCNAFTGC-NH2 (ProPheCysAsnAlaPheTyrGlyCys-NH2) and a disulfide bridge between Cys3 and Cys9. It is fou...
T10218	Abatacept	CTLA4lg	Others
	Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extracellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains). It is a selective T-cell co-stimulation ...		Others
T64239	Belatacept
	Belatacept (BMS 224818) is a selective blocker of T-cell costimulation. Belatacept binds CD 80/86 ligands and thus exhibits an inhibitory effect on CD-28-mediated T-cell costimulation. Belatacept can be used to study org...
T24705	Ramentaceone	NSC-208733,NSC 624625,NSC 208733,NSC208733,NSC-624625
	Ramentaceone is an antineoplastic.
T82666	Crustacean cardioactive peptide	CCAP
	Crustacean cardioactive peptide (CCAP) is an insect cardioregulatory peptide containing nine amino acids, initially isolated from Manduca sexta, the tobacco hawkmoth. It features two cysteines at positions 3 and 9 that f...
T6009	TAPI1	TAPI 1,TAPI,TAPI-1	MMP
	TAPI1 (TAPI) , an ADAM17/TACE inhibitor, inhibits shedding of cytokine receptors.		MMP
T4368	Miriplatin	SM-11355	DNA Alkylator/Crosslinker
	Miriplatin (SM-11355) (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).		DNA Alkylator/Crosslinker
T30531L	BMS-561392 Formic acid	BMS-561392 Formic acid(611227-74-8 Free base)	MMP
	BMS-561392 Formic acid is a selective inhibitor of TACE and reduces TNFalpha levels.		MMP
T21297	Miriplatin hydrate	SM-11355 (hydrate),Miripla,Miriplatin,SM 11355,SM11355,SM-11355,Miriplatin hydrate	DNA Alkylation
	Miriplatin hydrate (SM-11355 (hydrate)) (MPT) is a novel platinum complex used in TACE that shows promise for the treatment of hepatocellular carcinoma (HCC). Miriplatin hydrate is a lipophilic platinum complex that can ...		DNA Alkylation
T7522	GI254023X	GI 254023X	MMP , Immunology/Inflammation related
	GI254023X is a potent MMP9 and ADAM10 inhibitor (IC50s: 2.5 and 5.3 nM) with 100-fold selectivity for the α-secretase ADAM10 over ADAM17 (TACE). GI254023X can remarkably inhibit the proliferation and induce the apoptosis...		MMP , Immunology/Inflammation related
TP2107	TAPI 0
	ADAM-17 (TACE) and MMP inhibitor; attenuates TNF-α processing. Acts in concert with GM6001 to inhibit Chlamydia trachomatis growth.
T69181	BMS-566394
	BMS-566394 is a potent, exceptionally selective inhibitor of TNF-α converting enzyme (TACE).
T4122	TAPI-1 trifluoroacetate (163847-77-6(free base))		MMP
	TAPI-1 is an ADAM17/TACE inhibitor, which blocks shedding of cytokine receptors.		MMP
T27592	IK-862	IK 862
	IK-862 is a selective inhibitor of TACE (ADAM17).
T27507	GW-3333	GW 3333,GW3333
	GW-3333 is an matrix metalloproteinase inhibitor. It is also a tumor necrosis factor-alpha (TNF)-Converting Enzyme (TACE) inhibitor. The efficacy of GW3333 suggests that dual inhibitors of matrix metalloproteinases and T...