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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5552 | Methyl cinnamate | Tyrosinase , Antibacterial , AMPK | |
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects. | |||
T81105 | SREBP/SCAP-IN-1 | ||
SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1]. | |||
T7798 | FGH10019 | FGH-10019 | NPC1L1 , Fatty Acid Synthase |
FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM). | |||
T9266 | Fatostatin | Lipid , Fatty Acid Synthase | |
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. | |||
T6832 | Fatostatin hydrobromide | Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin | NPC1L1 , Fatty Acid Synthase |
Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2. | |||
T4317 | PF 429242 | NPC1L1 , Lipid | |
PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rat... | |||
T12437 | PF429242 dihydrochloride | S1P Receptor | |
PF429242 dihydrochloride is a reversible and competitive inhibitor of S1P (IC50 of 175 nM). | |||
T27478 | GSK3987 | Liver X Receptor | |
GSK3987 is an LXR ligand. GSK3987 recruits the steroid receptor coactivator-1 to human LXRalpha and LXRbeta with EC50s of 40 nM. | |||
T81104 | SREBP/SCAP-IN-2 | ||
SREBP/SCAP-IN-2 (compound 13) acts as a selective inhibitor of SREBP/SCAP [1]. | |||
T74147 | Larsucosterol (trimethylamine) | ||
Larsucosterol (DUR-928) trimethylamine, a metabolite of cholesterol, functions as a powerful liver X receptor (LXR) antagonist, effectively reducing lipogenesis and inhibiting cholesterol biosynthesis. It achieves this b... | |||
T64171 | LXR antagonist 2 | ||
LXR antagonist 2 (compound 10rr) is a potent LXR (liver X receptor) inverse agonist, acting on LXRβ (IC50: 0.36 μM) and LXRα (IC50: 2.25 μM). LXR antagonist 2 is an adipogenesis inhibitor that downregulates LXR target ge... |