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20

Compounds

Cat No. Product Name Synonyms Targets
T28758 SERT inhibitor 69419
SERT inhibitor 69419 inhibits serotonin reuptake.
T73273 SERT-IN-2
SERT-IN-2, a potent SERT inhibitor (IC 50 = 0.58 nM), exhibits promising efficacy as an anti-depressant. It demonstrates a favorable bioavailability of 83.28% in rats and has the ability to cross the blood-brain barrier.
T72824 RAGE/SERT-IN-1
RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM and 31.09 nM, respectively. It demonstrates a significant neurop...
T8708 Paroxetine Serotonin Transporter
Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.
T12232 Nitroxazepine CIBA 2330Go Serotonin Transporter
Nitroxazepine (CIBA 2330Go) is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression
T7061 Duloxetine Serotonin Transporter
Duloxetine is an inhibitor of serotonin-norepinephrine reuptake(Ki of 4.6 nM),with treatment of major depressive disorder and generalized anxiety disorder.
T0450 Fluoxetine LY-110140 5-HT Receptor , Serotonin Transporter , MRP , Autophagy
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity.
T22714 Decynium 22 Others
Decynium 22 is a plasma membrane monoamine transporter (PMAT) inhibitor
T22453 Venlafaxine Wy 45030 Serotonin Transporter
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.
T7521 Azaphen Pipofezin hydrochloride,Pipofezine hydrochloride,Azafen 5-HT Receptor , Serotonin Transporter
Azaphen (Pipofezin hydrochloride) is the reuptake of serotonin inhibitor.with antidepressant action and has sedative effects, suggesting antihistamine activity.
T2594 Dextromilnacipran Levomilnacipran Serotonin Transporter , Norepinephrine
Dextromilnacipran (Levomilnacipran) is a selective serotonin and norepinephrine reuptake inhibitor.
T1189 Milnacipran hydrochloride Milnacipran HCl,Savella,Dalcipran Serotonin Transporter , Norepinephrine
Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is an enantiomer of milnacipran, which is used to treat fibromy...
TQ0311 GSK163090 Dopamine Receptor , 5-HT Receptor
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
T1317 Cinchonidine α-Quinidine,L-Cinchonidine 5-HT Receptor , Serotonin Transporter , Parasite
Cinchonidine (L-Cinchonidine) is an alkaloid extracted from Cinchona officinalis. It is a pseudo-enantiomer and stereoisomer of cinchonine.
T0482 Sertraline hydrochloride Sertraline HCl,CP-51974-1 HCl 5-HT Receptor , Serotonin Transporter
Sertraline hydrochloride (Sertraline HCl) is a selective serotonin uptake inhibitor that is used in the treatment of depression.
T10758L Centanafadine hydrochloride EB-1020 hydrochloride Dopamine Receptor , Serotonin Transporter , Adrenergic Receptor , Norepinephrine
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin...
T2395 Vortioxetine Lu AA 21004 5-HT Receptor , Serotonin Transporter
Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment.
T11087 DOV-216,303 Free Base DOV-216303 Dopamine Receptor , Serotonin Transporter , Norepinephrine
DOV-216,303 Free Base (DOV-216303) is an inhibitor of serotonin, norepinephrine, and dopamine reuptake with with IC50s of 14, 20 and 78 nM. DOV-216,303 Free Base exhibits antidepressant effects.
T7940 Milnacipran ((1S-cis) hydrochloride) Levomilnacipran Hydrochloride Serotonin Transporter
Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.
T1580 Desvenlafaxine WY 45233 Succinate,O-Desmethylvenlafaxine 5-HT Receptor , Serotonin Transporter , Norepinephrine
Desvenlafaxine (O-Desmethylvenlafaxine) is a cyclohexanol and phenol derivative and metabolite of venlafaxine that functions as a serotonin and noradrenaline reuptake inhibitor (SNRI) and is used as an antidepressive age...

Compounds

SERT inhibitor 69419
T28758
Synonym:
Target:
SERT-IN-2
T73273
Synonym:
Target:
RAGE/SERT-IN-1
T72824
Synonym:
Target:
Paroxetine
T8708
Synonym:
Target: Serotonin Transporter
Nitroxazepine
T12232
Synonym: CIBA 2330Go
Target: Serotonin Transporter
Duloxetine
T7061
Synonym:
Target: Serotonin Transporter
Fluoxetine
T0450
Synonym: LY-110140
Target: 5-HT Receptor, Serotonin Transporter, MRP, Autophagy
Decynium 22
T22714
Synonym:
Target: Others
Venlafaxine
T22453
Synonym: Wy 45030
Target: Serotonin Transporter
Azaphen
T7521
Synonym: Pipofezin hydrochloride,Pipofezine hydrochloride,Azafen
Target: 5-HT Receptor, Serotonin Transporter
Dextromilnacipran
T2594
Synonym: Levomilnacipran
Target: Serotonin Transporter, Norepinephrine
Milnacipran hydrochloride
T1189
Synonym: Milnacipran HCl,Savella,Dalcipran
Target: Serotonin Transporter, Norepinephrine
GSK163090
TQ0311
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Cinchonidine
T1317
Synonym: α-Quinidine,L-Cinchonidine
Target: 5-HT Receptor, Serotonin Transporter, Parasite
Sertraline hydrochloride
T0482
Synonym: Sertraline HCl,CP-51974-1 HCl
Target: 5-HT Receptor, Serotonin Transporter
Centanafadine hydrochloride
T10758L
Synonym: EB-1020 hydrochloride
Target: Dopamine Receptor, Serotonin Transporter, Adrenergic Receptor, Norepinephrine
Vortioxetine
T2395
Synonym: Lu AA 21004
Target: 5-HT Receptor, Serotonin Transporter
DOV-216,303 Free Base
T11087
Synonym: DOV-216303
Target: Dopamine Receptor, Serotonin Transporter, Norepinephrine
Milnacipran ((1S-cis) hydrochloride)
T7940
Synonym: Levomilnacipran Hydrochloride
Target: Serotonin Transporter
Desvenlafaxine
T1580
Synonym: WY 45233 Succinate,O-Desmethylvenlafaxine
Target: 5-HT Receptor, Serotonin Transporter, Norepinephrine
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