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Search Results for " sag "

20

Compounds

Cat No. Product Name Synonyms Targets
T1779 SAG Smoothened Agonist (SAG) HCl,Smoothened Agonist Hedgehog/Smoothened , Smo
SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway.
T40465 SAG dihydrochloride Hedgehog/Smoothened
SAG dihydrochloride, a powerful agonist of the Smoothened (Smo) receptor (EC 50 = 3 nM; Kd = 59 nM), effectively activates the Hedgehog signaling pathway. It also negates the effects of Cyclopamine inhibition on Smo.
T35559 SAG 21k Hedgehog/Smoothened
SAG 21k is an orally bioactive and potent Hedgehog signaling activator that crosses the blood-brain barrier for the study of cartilage regeneration.
T4211 SAG hydrochloride (912545-86-9(free base)) Smoothened Agonist HCl Hedgehog/Smoothened
SAG hydrochloride (912545-86-9(free base)) (Smoothened Agonist HCl) acts as an SMO agonist.
T24754 Hh-Ag1.5 SAG-1.5,SAG1.5,SAG 1.5 Hedgehog/Smoothened
Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quies...
T20845 Kopexil Mexoryl SAG,Aminexil
Kopexil, an N-oxide, is used to treat hair loss.
T24159 IHR-1 IHR 1 Smo
IHR-1 is a Potent Smo antagonist (IC50 = 7.6 nM). Selectively inhibits Hedgehog signaling over Wnt and Notch signaling pathways. Blocks Smo accumulation in primary cilium in vitro.
T23027 MRT-10 Hedgehog/Smoothened
MRT-10 is a Smoothened (Smo) receptor antagonist.
T6962 Rasagiline Mesylate TVP1012,AGN1135,Azilect Apoptosis , MAO , Autophagy , Monoamine Oxidase
Rasagiline Mesylate (AGN1135) is a novel MAO-B inhibitor, which can treat idiopathic Parkinson's disease.
T17044 Tesaglitazar PPAR
Tesaglitazar is a potent and selective peroxide PPARα / γ receptor dual agonist with a more potent affinity for PPARγ than PPARα, The EC50 values for rat PPARα and human PPARα were 13.4 μM and 3.6 μM, respectively, and 0...
T1119 Rasagiline AGN1135,TVP1012 BCL , MAO , Monoamine Oxidase
Rasagiline (AGN1135) is an inhibitor of monamine oxidase used as adjunctive therapy in combination with levodopa and carbidopa in the management of Parkinsons disease.
T12693 Rasagiline 13C3 mesylate racemic TVP1012 13C3 racemic,AGN1135 13C3 racemic Others
Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.
T8683 Mipsagargin G-202 Others
Mipsagargin (G-202) is a new antibiotic that inhibits DNA biosynthesis.
T28995 Tosagestin Org 30659,Org30659,Org-30659
Tosagestin is a progesterone receptor agonist.
T82346 Galanin message associated peptide (1-41) amide
Galanin message-associated peptide (1-41) amide is a peptide hormone [1].
T36903 Rasagiline-13C3 (mesylate) Rasagiline-13C3 (mesylate)
Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is se...
T71910 Racemic rasagiline
Racemic rasagiline, also known as AGN-1135, is a Monoamine Oxidase type-B inhibitor (MAOI). However, application of this drug can lead to fatal hypertensive crisis in patients who consume tyramine-rich foods. TVP-102...
TQ0163 Sagittatoside A Icariin-A Estrogen/progestogen Receptor
Sagittatoside A selectively activates estrogen response element (ERE)-luciferase activity via ERα.
T81482 Physagulide J
Physagulide J, a withanolide compound extracted from Physalis angulata L., exhibits anti-inflammatory and anti-tumor properties [1].
TN2168 Sagittatoside C Others
Sagittatoside C is a natural product
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TargetMol