rad51 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T9271	RAD51-IN-1		DNA/RNA Synthesis
	Rad51-in-1 is a derivative of B02 and an effective inhibitor of Rad51.		DNA/RNA Synthesis
T4656	RAD51 Inhibitor B02	B02	Apoptosis , DNA/RNA Synthesis
	RAD51 Inhibitor B02 (B02) (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.		Apoptosis , DNA/RNA Synthesis
T39824	RAD51-IN-3	RAD51-IN-3
	RAD51-IN-3 is a Rad51 inhibitor.
T12682	Emzadirib	CYT-0851,RAD51-IN-2	DNA/RNA Synthesis
	Emzadirib (RAD51-IN-2) is a potent RAD51 inhibitor with potential anticancer activity for the study of DNA damage repair.		DNA/RNA Synthesis
T2276	RI-1	RI1,RAD51 inhibitor 1	DNA/RNA Synthesis
	RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).		DNA/RNA Synthesis
T63892	RAD51-IN-5
	RAD51-IN-5 is a potent inhibitor of RAD51. RAD51-IN-5 has shown potential for the study of mitochondrial deficiency disorders.
T61469	RAD51-IN-8
	RAD51-IN-8, a new RAD51 binder, is a RAD51-BRCA2 inhibitor that inhibits the RAD51 BRCA2 protein protein interaction in the micromolar range. RAD51-IN-8 also is a protein protein interaction (PPI) inhibitor. RAD51-IN-8 h...
T63728	RAD51-IN-7
	RAD51-IN-7 is a potent inhibitor of RAD51, a eukaryotic gene. RAD51-IN-7 has shown research potential for mitochondrial deficiency disorders.
T63883	RAD51-IN-6
	RAD51-IN-6 is a potent inhibitor of RAD51, which is a eukaryotic gene. RAD51-IN-6 has shown potential for the study of mitochondrial deficiency disorders.
T73107	RAD51-IN-4
	RAD51-IN-4 is a potent RAD51 inhibitor, targeting a eukaryote gene critical for studies on conditions associated with mitochondrial defects.
T2628	RI-2		DNA/RNA Synthesis
	RI-2 is an optimized RAD51 inhibitor with an IC50 of 44.17 μM in the standard DNA binding assay; specifically inhibits HR(Homologous recombination) repair in human cells.		DNA/RNA Synthesis
T11600	IBR2	Isoquinoline	DNA/RNA Synthesis
	IBR2 (Isoquinoline) is a potent and specific RAD51 inhibitor known for its ability to suppress RAD51-mediated DNA double-strand break repair. By interfering with RAD51 multimerization, accelerating proteasome-mediated RA...		DNA/RNA Synthesis
T6972	RS-1		DNA/RNA Synthesis
	RS-1 is a RAD51 activator. RS-1 also increases CRISPR/Cas9-mediated knock-in efficiencies.		DNA/RNA Synthesis
T8873	Bractoppin		Others , DNA/RNA Synthesis
	Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi...		Others , DNA/RNA Synthesis
T9168	NSC 617145	NSC617145,NSC-617145	DNA/RNA Synthesis
	NSC 617145 (NSC617145) is an inhibitor of WRN helicase that inhibits the ATPase, but not exonuclease, activity of WRN helicase in a concentration-dependent manner.		DNA/RNA Synthesis
T2516	Amuvatinib	MP470,HPK 56	Apoptosis , FLT , c-Met/HGFR , c-RET , DNA/RNA Synthesis , PDGFR , c-Kit
	Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.
T60006	Aromatase inhibitor 23		Others
	Aromatase inhibitor 23 is an inhibitor that target protein-protein interactions in RAD51 family of recombinases.		Others
T10936	D-I03	DI03	DNA/RNA Synthesis
	D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 µM. D-I03 specifically inhibits RAD52-dependent single-chain annealing (SSA) and D-loop formation, with IC50 of 5 µM and 8 µM, respectively. D-I03 inhibited the grow...		DNA/RNA Synthesis
T6960L	PU-H71 HCl	PU-H71 HCl(873436-91-0 Free base),Zelavespib HCl	HSP , DNA/RNA Synthesis
	PU-H71 HCl (Zelavespib HCl) is a novel Hsp90 inhibitor, a novel purine-based analog, and a radiosensitizer that may be a promising agent for CIRT. PU-H71 HCL shows antitumor activity in many preclinical models of maligna...		HSP , DNA/RNA Synthesis
T63717	CAM833
	CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 and also inhibits RAD51 oligomerization and is able to act on the ChimRAD51 protein (Kd: 366 nM).