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Search Results for " qtc "

7

Compounds

Cat No. Product Name Synonyms Targets
T1676 Rosuvastatin ZD 4522 Potassium Channel , HMG-CoA Reductase , Autophagy
Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting...
T1510 Rosuvastatin calcium ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium Potassium Channel , HMG-CoA Reductase , Autophagy
Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity.
T2170 SKF-96365 hydrochloride SKF96365 Apoptosis , Potassium Channel , Calcium Channel , TRP/TRPV Channel , Autophagy
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha...
T73367 Zn(BQTC) DNA/RNA Synthesis
Zn(BQTC) is a potent inhibitor of both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA), causing significant damage that disrupts mitochondrial and nuclear functions sequentially. It facilitates apoptotic signaling pathw...
T71945 Eleclazine free base
Eleclazine, also known as GS-6615, is a selective late sodium current inhibitor. Eleclazine is potentially useful for treatment of coronary vasodilators, antiarrhythmics and vasodilators. Eleclazin showed a shortening of...
TP2072 BeKm-1
Potent and selective KV11.1 (hERG) channel blocker. Selective for KV11.1 over a panel of 14 other potassium channels. Dose-dependently prolongs QTc interval in isolated rabbit heart.
T75953 BeKm-1 TFA
BeKm-1 TFA is a potent, selective blocker of the KV11.1 (hERG) channel, demonstrating specificity for KV11.1 over 14 other potassium channels. This compound dose-dependently prolongs the QTc interval in isolated rabbit h...
TargetMol