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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1676 | Rosuvastatin | ZD 4522 | Potassium Channel , HMG-CoA Reductase , Autophagy |
Rosuvastatin (ZD 4522) is an antilipemic agent that competitively inhibits hydroxymethyl-glutaryl-coenzyme A (HMG-CoA) reductase. HMG-CoA reductase catalyzes the conversion of HMG-CoA to mevalonic acid, the rate-limiting... | |||
T1510 | Rosuvastatin calcium | ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium | Potassium Channel , HMG-CoA Reductase , Autophagy |
Rosuvastatin calcium (ZD4522) , a selective and competitive inhibitor of hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, has antilipidemic activity. | |||
T2170 | SKF-96365 hydrochloride | SKF96365 | Apoptosis , Potassium Channel , Calcium Channel , TRP/TRPV Channel , Autophagy |
SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal Y cells. SKF-96365 hydrochloride can induce cytoprotective autopha... | |||
T73367 | Zn(BQTC) | DNA/RNA Synthesis | |
Zn(BQTC) is a potent inhibitor of both mitochondrial DNA (mtDNA) and nuclear DNA (nDNA), causing significant damage that disrupts mitochondrial and nuclear functions sequentially. It facilitates apoptotic signaling pathw... | |||
T71945 | Eleclazine free base | ||
Eleclazine, also known as GS-6615, is a selective late sodium current inhibitor. Eleclazine is potentially useful for treatment of coronary vasodilators, antiarrhythmics and vasodilators. Eleclazin showed a shortening of... | |||
TP2072 | BeKm-1 | ||
Potent and selective KV11.1 (hERG) channel blocker. Selective for KV11.1 over a panel of 14 other potassium channels. Dose-dependently prolongs QTc interval in isolated rabbit heart. | |||
T75953 | BeKm-1 TFA | ||
BeKm-1 TFA is a potent, selective blocker of the KV11.1 (hERG) channel, demonstrating specificity for KV11.1 over 14 other potassium channels. This compound dose-dependently prolongs the QTc interval in isolated rabbit h... |