ptpn6 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8478	SC-43		Apoptosis , Phosphatase , STAT
	SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.

Recombinant Proteins

Species：

Expression System：

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Cat No.	Product Name	Species	Expression System
TMPJ-00465	PTP1C Protein, Human, Recombinant (His)	Human	E. coli
	Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mi...
TMPJ-00387	IL-4R alpha Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions a...
TMPY-06052	SIRP alpha V2 Protein, Human, Recombinant (His)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-01573	SIRP alpha Protein, Human, Recombinant (G75A, His)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-02632	SIRP alpha Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-05841	SIRP alpha Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06051	SIRP alpha Protein, Human, Recombinant (hFc)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-03296	SHP-1 Protein, Mouse, Recombinant (aa 207-597, His & GST)	Mouse	Baculovirus-Insect Cells
	PTPN6 is an enzyme that belongs to the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and onco...
TMPH-01045	CEACAM1 Protein, Human, Recombinant	Human	E. coli
	Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
TMPK-00177	LAIR1 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	LAIR1 (leukocyte-associated Ig-like receptor-1, designated CD305) is an approximately 40 kDa type I transmembrane inhibitory glycoprotein belonging to the Ig superfamily.LAIR1 functions as an inhibitory receptor that pla...
TMPK-01066	BTLA Protein, Human, Recombinant (His & Avi)	Human	HEK293
	B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates anti...
TMPK-00530	BTLA Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates anti...
TMPJ-00898	CD72 Protein, Human, Recombinant (Trx & His)	Human	E. coli
	B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, mon...
TMPH-01044	CEACAM1 Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	Cell adhesion protein that mediates homophilic cell adhesion in a calcium-independent manner. Plays a role as coinhibitory receptor in immune response, insulin action and functions also as an activator during angiogenesi...
TMPJ-00193	TREML1 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-...
TMPJ-00305	SIRP alpha Protein, Cynomolgus, Recombinant (aa 31-369, His)	Cynomolgus	Human Cells
	Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre...
TMPJ-01183	SIRP alpha Protein, Mouse, Recombinant (aa 32-373, His)	Mouse	Human Cells
	Mouse Signal Regulatory Protein α (SIRPα) is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain. Mouse SIRP alpha ECD shares 61%, 75%, 62%, 61%, and 59% aa sequence ...
TMPJ-00306	SIRP alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	Signal Regulatory Protein α (SIRPα) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRPα contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRPα can expre...
TMPJ-00179	LAIR1 Protein, Human, Recombinant (aa 22-163, His & Avi), Biotinylated	Human	Human Cells
	Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) is a single-pass type I membrane protein. LAIR1 expressed on the majority of peripheral mononuclear cells, including natural killer (NK) cells, T-cells, B-cells...
TMPH-03267	CD300f/CD300LF Protein, Rat, Recombinant (His & Myc & SUMO)	Rat	E. coli
	Acts as an inhibitory receptor for myeloid cells and mast cells. Positively regulates the phagocytosis of apoptotic cells (efferocytosis) via phosphatidylserine (PS) recognition; recognizes and binds PS as a ligand which...
TMPJ-01182	SIRP alpha Protein, Mouse, Recombinant (MIgG2a)	Mouse	Human Cells
	SIRPα is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain. Mouse SIRP alpha ECD shares 61%, 75%, 62%, 61%, and 59% aa sequence identity with human, rat, equine, bo...
TMPJ-01181	SIRP alpha Protein, Mouse, Recombinant (aa 32-373, hFc)	Mouse	Human Cells
	Mouse Signal Regulatory Protein α (SIRPα) is a type I transmembrane glycoprotein.It contains two Ig-like C1-type domains and one Ig-like V-type domain. Mouse SIRP alpha ECD shares 61%, 75%, 62%, 61%, and 59% aa sequence ...
TMPJ-00427	LAIR1 Protein, Rhesus macaque, Recombinant (His)	Rhesus Macaque	Human Cells
	Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) is a single-pass type I membrane protein. LAIR1 expressed on the majority of peripheral mononuclear cells, including natural killer (NK) cells, T-cells, B-cells...
TMPH-02962	Lyn Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Non-receptor tyrosine-protein kinase that transmits signals from cell surface receptors and plays an important role in the regulation of innate and adaptive immune responses, hematopoiesis, responses to growth factors an...
TMPY-06054	SIRP alpha V8 Protein, Human, Recombinant (His)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-05126	SIRP alpha Protein, Human, Recombinant (G75A, His), Biotinylated	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06053	SIRP alpha V2 Protein, Human, Recombinant (mFc)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06248	SIRP alpha V2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06055	SIRP alpha V8 Protein, Human, Recombinant (mFc)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-06284	SIRP alpha Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-05745	SIRP alpha Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-02636	SIRP alpha Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-05263	SIRP alpha Protein, Human, Recombinant (mFc)	Human	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...
TMPY-03666	SIRP alpha Protein, Rat, Recombinant (His)	Rat	HEK293
	Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig...