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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN7054 | N-Formylcytisine | (-)-N-Formylcytisine | Others |
N-Formylcytisine ((-)-N-Formylcytisine) is a natural product isolated from the stem bark of Maackia amurensis. | |||
T12153 | N-type calcium channel blocker-1 | Calcium Channel | |
N-type calcium channel blocker-1 is an orally active analgesic agent,shows high affinity to functionally block N-type calcium channels. | |||
T12039 | Miglustat | N-Butyldeoxynojirimycin,OGT918,NB-DNJ | Others |
Miglustat (NB-DNJ) is an alkylated product of imino sugar deoxynojirimycin.It is an inhibitor of glucosylceramide synthase, primarily to treat Type I Gaucher disease (GD1). | |||
TQ0155 | Miglustat hydrochloride | NB-DNJ hydrochloride,N-Butyldeoxynojirimycin hydrochloride,OGT918 hydrochloride | Transferase |
Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I Gaucher disease. | |||
T12302 | OMDM-1 | (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide | Endogenous Metabolite |
OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) is a selective and metabolically stable anandamide cellular uptake (ACU)inhibitor with a Ki of 2.4 μM. | |||
T21900 | ML-336 | Others | |
ML-336 is an inhibitor of of the Venezuelan equine encephalitis virus (VEEV) strain TC-83. | |||
TP1559L | Ziconotide Acetate (107452-89-1 free base) | Prialt,Ziconotide Acetate | Calcium Channel |
Ziconotide Acetate (107452-89-1 free base) (Prialt) is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide Acetate (107452-89-1 free base) acts by binding to N-type calcium chan... | |||
T7334 | NP118809 | 39-1B4 | Calcium Channel |
NP118809 (39-1B4) is a potent N-type calcium channel blocker(IC50 : 0.11 μM). | |||
T11517 | GV-58 | Calcium Channel | |
GV-58 is a selective N- and P/Q-type Ca2+ channels agonist (EC50: 7.21/8.81 uM for N-type/P-Q-type Ca2+ channel). The inhibitory of GV-58 is 20-fold fewer for CDK kinases activity. | |||
T10659 | Ca2+ channel agonist 1 | Calcium Channel , CDK | |
Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2 (EC50s: 14.23 μM and 3.34 μM) and is used as a potential treatment for motor nerve terminal dysfunction. | |||
T12385 | PD0176078 | PD176078 | Calcium Channel |
PD0176078 () is a newly blocker of N-type Calcium channel. | |||
T4462 | Roflumilast N-oxide | PDE | |
Roflumilast N-oxide is an inhibitor of PDE type 4. | |||
T6S1500 | Ginsenoside Rf | Ginsenoside-Rf,Panaxoside Rf | Calcium Channel , Endogenous Metabolite |
Ginsenoside Rf (Panaxoside Rf) is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channel. | |||
T10690 | Cav 2.2 blocker 1 | Calcium Channel | |
Cav 2.2 blocker 1 is an N-type calcium channel (Cav 2.2; IC50: 1 nM) blocker for the treatment of pain. | |||
T0388 | Cilnidipine | FRC-8653 | Calcium Channel |
Cilnidipine (FRC-8653)(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity. | |||
T36061 | N-Desmethyl Sildenafil | Desmethylsildenafil,UK-103,320 | Drug Metabolite |
N-Desmethyl Sildenafil (UK-103,320) (Desmethylsildenafil) is a prominent metabolite of Sildenafil, a potent inhibitor of phosphodiesterase type 5 (PDE5). | |||
T16339 | Norverapamil hydrochloride | (±)-Norverapamil hydrochloride,D591 hydrochloride | Calcium Channel , P-gp , Drug Metabolite |
Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor. | |||
T16240 | N,N'-Diacetyl-L-cystine | (Ac-Cys-OH)2,DiNAC | Others |
N,N'-Diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL... | |||
T16448 | PD173212 | Calcium Channel | |
PD 173212 is a blocker that blocks N-type voltage sensitive calcium channel (Cav2.2). PD173212 (0.0017-1.7 μmol/kg, Intraperitoneal Injection.) dose-dependently reduced DNBS-induced visceral hypersensitivity in mice. | |||
T16164 | MY-5445 | N-(3-chlorophenyl)-4-phenylphthalazin-1-amine | PDE |
MY-5445 (N-(3-chlorophenyl)-4-phenylphthalazin-1-amine) is a specific inhibitor of phosphodiesterase type 5 (PDE5). MY-5445 selectively inhibits cGMP PDE (Ki:1.3 μM). |