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Search Results for " n-smase "

7

Compounds

Cat No. Product Name Synonyms Targets
T60043 DPTIP Phospholipase
DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.
T0674 Lansoprazole A-65006,AG-1749 Proton pump , Phospholipase , Antibacterial
Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is fo...
T3640 GW4869 GW554869A,GW 4869,GW69A Phospholipase
GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 μM). GW4869 also inhibits exosome synthesis/release and is commonly used in exosome-related studies.
T0757 Omeprazole Losec,Prilosec,H 16868,Antra Proton pump , Phospholipase , Antibacterial , Autophagy
Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
T1021 (R)-Lansoprazole Dexlansoprazole,T 168390,TAK 390,R-(+)-Lansoprazole Proton pump
(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity.Lansoprazole (AG 1749) is a potent brain penetrant neutra...
T22391 Omeprazole Sodium P450 , Proton pump , Antibacterial , Autophagy
Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive...
T4019 Cambinol SIRT1/2 Inhibitor IV,NSC 112546 Apoptosis , Phospholipase , Sirtuin
Cambinol (SIRT1/2 Inhibitor IV) is a cell-permeable b-naphthol compound that inhibits the NAD-dependent deacetylase activity of SIRT1/2 (IC50: 56/59 μM, respectively) in a substrate-, but not NAD-, competitive manner. Ca...
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