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Search Results for " ms4 "

16

Compounds

Cat No. Product Name Synonyms Targets
T71346 MS4
MS4 is a novel glucocorticoid receptor (GR) agonist with anti-inflammatory activity and displaying reduced impact on islets.
T16153 MS4078 ALK , Ligand for E3 Ligase , PROTACs
MS4078 is an inhibitor and aplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19 nM for binding affinity to ALK.
T16154 MS417 GTPL7512 Epigenetic Reader Domain , HIV Protease
MS417 (GTPL7512) is an inhibitor of BET-specific BRD4(BRD4-BD1 and BRD4-BD2 with IC50s of 30, 46 nM and Kds of 36.1, 25.4 nM, respectively), with weak selectivity at CBP BRD with IC50 of 32.7 μM.
T12112 MS402 Epigenetic Reader Domain
MS402 is a novel BD1-selective BET BrD inhibitor.
T21714 BMS453 BMS 453,BMS-189453 Retinoid Receptor
BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin. BMS453 inhibits breast cell growth predominantly through the induction of active TGFβ.
T14689 BMS493 BMS-493 Phospholipase , Retinoid Receptor
BMS493 is an inverse agonist of the pan-retinoic acid receptor (RAR) that inhibits retinoic acid-induced differentiation, enhances the interaction of nuclear co-inhibitors with RARs, attenuates RA signaling, potentiates ...
T40233 (Iso)-MS4322 (Iso)-YS43-22,MS4322 (isomer),YS43-22 (isomer) Histone Methyltransferase , PROTACs
(Iso)-MS4322 ((Iso)-YS43-22) is a selective and potent protein arginine methyltransferase 5 (PRMT5) degrader with potential anticancer activity that effectively reduces PRMT5 protein levels in MCF-7 cells and inhibits th...
T9146 ms48107 Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro- Others
MS48107 is a potent, selective positive allosteric modulator of G protein-coupled receptor 68 (GPR68), demonstrating specificity for GPR68 over closely related proton GPCRs, neurotransmitter transporters, and hERG ion ch...
T1854 MS436 Epigenetic Reader Domain
MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.
T28116 MS453 MS-453,MS 453
MS453 is a potent and selective SETD8 inhibitor with an IC50 value of 804 nM.
T24502 MS437 MS 437,MS-437
MS437 is a potent TSH receptor agonist.
T73433 MS47134
MS47134, a selective and potent MRGPRX4 agonist, exhibits an EC50 of 149 nM and holds potential for researching pain, itch, and mast cell-mediated hypersensitivity.
T82378 Folate-MS432 PROTACs
Folate-MS432 is a PROTAC that degrades MEKs selectively in cancer cells via folate receptor-dependent pathways.
T13781 MS4077 ALK , PROTACs
MS4077 is an degrader of anaplastic lymphoma kinase (ALK) PROTAC(Kd of 37 nM for binding affinity to ALK).
T24503 MS438 MS-438,MS 438
MS438 is an effective agonist of the TSH receptor.
T13782 MS432 MEK , PROTACs
MS432 is a highly selective PD0325901-based VHL-recruiting PROTAC degrader for MEK1 and MEK2.
TargetMol