20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1171L | Methylprednisolone Aceponate | MPA,SH 440,SH-440,SH440,Advantan | Others |
Methylprednisolone Aceponate (SH 440), a non-halogenated corticosteroid, is a potent anti-inflammatory agent. | |||
T19416 | Medroxyprogesterone acetate D3 | MPA D3,Medroxyprogesterone 17-acetate D3 | Others |
Medroxyprogesterone acetate D3 is deuterium labeled Medroxyprogesterone acetate. Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors. | |||
T67798 | (2RS)-FPMPA | FPMPA | HIV Protease |
(2RS)-FPMPA(FPMPA) has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R). | |||
T13173 | TMPA | Others , AMPK | |
TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist. | |||
T11186 | EMPA | OX Receptor | |
EMPA is a selective, high-affinity and reversible antagonist of orexin OX2 receptor(human and rat OX2-HEK293 membranes with KD values of 1.1 and 1.4 nM respectively) | |||
T1766 | Empagliflozin | BI 10773 | SGLT |
Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6. Empagliflozin is used for the treatment of type 2 diabetes. | |||
T61813 | AMPA receptor antagonist-3 | iGluR | |
AMPA receptor antagonist-3 is an AMPA receptor antagonist. | |||
T3440 | 2-PMPA | 2-(Phosphonomethyl)pentanedioic acid | Carboxypeptidase |
2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a potent and selective inhibitor of glutamate carboxypeptidase II (GCPII) (IC50=300 pM). | |||
T34609 | Selurampanel | BGG-492,BGG 492,BGG492 | iGluR |
Selurampanel (BGG492) is an orally active and selective competitive AMPA glutamate receptor antagonist, a quinazoline-dione sulfonamide. selurampanel is used in the study of epilepsy, migraine and tinnitus. | |||
T17179 | Tulrampator | CX-1632,S-47445 | iGluR |
Tulrampator (S-47445) is an orally bioavailable positive AMPAR with antidepressant effects. | |||
T16977 | Talampanel | GYKI-53773,LY-300164 | Apoptosis , GluR |
Talampanel (LY-300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor antagonist with anti-seizure activity. Talampanel (IVAX) has neuroprotective effects in rodent stroke models. | |||
T61068 | AMPA receptor antagonist-2 | iGluR | |
AMPA receptor antagonist-2 is an AMPA receptor antagonist. | |||
T37734 | AMPA receptor modulator-2 | GluR | |
AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. [1]. BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AM... | |||
T21761 | HNMPA | IGF-1R | |
HNMPA is a membrane impermeable inhibitor of insulin receptor tyrosine kinase. HNMPA inhibits tyrosine and serine autophosphorylation by the human insulin receptor. HNMPA exhibits no effect on cyclic AMP-dependent prote... | |||
T19232 | CMC-Na (Viscosity:800-1200 mPa.s) | CMC-Na (Viscosity:800-1200 mPa.s) | Others |
Sodium carboxymethyl cellulose (CMC-Na) (Viscosity:800-1200 mPa.s) is a water-soluble cellulose, commonly used as a co-solvent in animal experiments, and is essentially non-toxic to animals. | |||
T3957 | Farampator | Org24448,CX-691 | GluR , iGluR |
Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor. | |||
T10307 | AMPA receptor modulator-1 | iGluR | |
AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels. | |||
T31208 | Dasolampanel | NGX-426,NGX 426,NGX426 | GluR , iGluR |
Dasolampanel (NGX-426) is an orally available ionotropic glutamate receptor AMPA and Kainate receptor antagonist for the study of chronic pain disorders, including neuropathic pain and migraine. | |||
T15820 | Mibampator | LY451395 | iGluR |
Mibampator (LY451395) is an effective and selective AMPA receptor potentiator. | |||
T79191 | AMPA receptor modulator-5 | iGluR | |
AMPA Receptor Modulator-5 (Example 217) serves as an AMPA receptor modulator, utilized in neurological disease research [1]. |