ml 10 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T33448	ML 10	ML-10,ML10
	ML 10 is is a [18F] positron emission tomography (PET) radiotracer that accumulates in cells presenting apoptosis-specific membrane alterations. [18F]ML-10 allows for the detection of apoptotic cells located in atheroscl...
T3757	NQ301		Thrombin , Platelet aggregation
	NQ301, an antithrombotic agent, inhibits collagen-challenged rabbit platelet aggregation (IC50: 10 mg/mL).		Thrombin , Platelet aggregation
T22990	ML-090	Fluoflavine	NADPH-oxidase , Others
	ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).		NADPH-oxidase , Others
T6856	Halofuginone	Tempostatin,empostatin,RU-19110	Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
	Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
TN3049	4-Methoxycinnamyl alcohol		Others
	4-Methoxycinnamyl alcohol showed toxicity to MCF-7, HeLa and DU145 cancer cell lines with IC50 values of 14.24, 7.82 and 22.10 μg/mL, respectively. 4-Methoxycinnamyl alcohol was isolated from Foeniculum vulgare. 4-Methox...		Others
T12075	ML-180	SR1848	Others
	ML-180 (SR1848) is a potent orphan nuclear receptor liver receptor homolog 1 (LRH-1; NR5A2) inverse agonist (IC50 of 3.7 μM) .		Others
T3868	Agnuside	chasteberry oil	COX , Prostaglandin Receptor , P-gp
	Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at conce...		COX , Prostaglandin Receptor , P-gp
T8974	ML-211		Others
	ML-211 is a carbamate-based dual inhibitor of LYPLA1 (IC50 = 17 nM) and the related LYPLA2 (IC50 = 30 nM)		Others
TN1453	Bruceantinol		Anti-infection
	Bruceantinol has antiviral activity, it can inhibit pepper mottle virus in pepper; it shows antibabesial activity against Babesia gibsoni in vitro, with the IC50 value of 12 ng/mL.		Anti-infection
T37341	N-Acetyltyramine		Antibacterial
	N-acetyltyramine is a metabolite of the biogenic amine tyramine . It enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells with an IC50 value of 0.13 μg/ml compared with an IC50 value of 0.48 μg/ml...		Antibacterial
T35912	Pyrocoll
	Pyrocoll is a bacterial metabolite originally isolated from Streptomyces. It inhibits the growth of A. aurescens, A. globiformis, A. oxydans, A. pascens, and R. erythropolis bacteria (MICs = 10, 1, 10, 3, and 10 μg/ml, r...
T61602	Anticancer agent 35
	Anticancer agent 35 (compound 10), a sulfonylurea derivative, is a potent anticancer agent. Anticancer agent 35 inhibits A549, A431, PACA2 cell growth with IC 50 s of 18.1 μg/mL, 4.0 μg/mL, 18.9 μg/mL, respectively [1].
T80407	Peptide 5g
	Peptide 5g, an antimicrobial peptide, inhibits E. coli, S. aureus, and C. albicans, exhibiting minimum inhibitory concentration (MIC) values of 30, 10, and 12.5 μg/mL, respectively [1].
T83031	Antioxidant agent-10
	Antioxidant Agent-10 (Compound 3) demonstrates moderate DPPH scavenging activity, possessing an EC50 value of 33.2 μg/mL [1].
T83467	10-O-Trans-p-methoxycinnamoylcatalpol
	10-O-Trans-p-methoxycinnamoylcatalpol exhibits antioxidant properties, demonstrated by an IC50 of 0.37 μM/mL in the DPPH free radical scavenging assay [1] [2].
T80377	Xenopsin precursor fragment		Parasite
	Xenopsin precursor fragment, an antimicrobial peptide, exhibits both antibacterial/antifungal activity at concentrations ranging from 10 to 500 μg/mL and anti-protozoal activity with a minimum inhibitory concentration (M...		Parasite
T27970	Mabuterol free base	Mabuterol,PB 868Cl	Others
	Mabuterol is a selective agonist of β2 adrenoreceptor with no beta 1-stimulation. Mabuterol inhibited the positive inotropic effect of isoprenaline at 10(-7) g/ml and decreased the maximum driving frequency at 3 X 10(-6)...		Others
T23954	Dactylfungin A
	Dactylfungins A is a novel antifungal antibiotic produced by Dactylaria Parvispora. The antibiotics were active against Candida pseudotropicalis and other fungi, with a MIC value of fewer than 10 micrograms/ml.
TN4651	Neuchromenin		Others
	(-)-Neuchromenin is an inducer of neurite outgrowth of PC12 cells at concentration of 2.5-10 ug/ml.		Others
T35607	10'-Desmethoxystreptonigrin
	10'-Desmethoxystreptonigrin is an antibiotic originally isolated from Streptomyces and a derivative of the antibiotic streptonigrin. It is active against a variety of bacteria, including S. aureus, S. faecalis, E. coli, ...