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Search Results for " mif "

20

Compounds

Cat No. Product Name Synonyms Targets
T60850 MIF-IN-2 Others
MIF-IN-2 is a heterocyclic macrophage migration inhibitory factor (MIF) inhibitor with anticancer activity for the study of cancer and autoimmune disorders.CAS 번호13460-73-86-5
T3680 ISO-1 MIF Antagonist,ISO 1 Others
ISO-1 (MIF Antagonist) is an inhibitor of the dopachrome tautomerase activity, blocks the activation of NF-κB and TNF-α secretion from LPS-treated macrophages.
T62344 MIF-IN-3
MIF-IN-3 is an inhibitor of migration inhibitory factor (MIF), which can be used in the study of immunoinflammation-related diseases.
T61218 MIF-IN-5
MIF-IN-5 (compound 1d) is a highly effective and reversible competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC 50 of 4.8 μM and a Ki value of 3.3 μM [1].
T60809 MIF-IN-1
MIF-IN-1 (compound 14) is a potent inhibitor of macrophage migration inhibitory factor (MIF) with pIC50 of 6.87. Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine associated with multiple disease...
T69525 MIF degrader MD13
MIF degrader MD13 is involved in protein-protein interactions that play key roles in inflammation and cancer. Current strategies to develop small molecule modulators of MIF functions are mainly restricted to the MIF taut...
T61705 MIF-IN-6
MIF-IN-6 (compound 2d) is an effective inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.4 μM and a Ki value of 0.96 μM. MIF-IN-6 effectively reduces MIF-induced ERK phosphorylation and i...
T73676 MIF-1 TFA
MIF-1 TFA (Melanostatin), an intrinsic brain peptide, serves as a powerful allosteric modulator of the dopamine receptor. It plays a crucial role in regulating melanin production and modifies the analgesic efficacy by in...
T76186 Tyr-W-MIF-1
Tyr-W-MIF-1, an opioid tetrapeptide, exhibits both opiate and antiopiate activities, and has been demonstrated to induce analgesia [1] [2] [5].
T63322 MIF-IN-4 hydrochloride
MIF-IN-4 hydrochloride is a potent inhibitor of macrophage mobility inhibitory factor (MIF) with pIC50 values ranging from 5.01-6. Where MIF was originally discovered as a cytokine in the process of inhibiting macrophage...
TN6730 Epoxyazadiradione NF-κB
Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NF-kB in human cervical cancer cells.
T7844 4-IPP 4-Iodo-6-phenylpyrimidine Others
4-IPP (4-Iodo-6-phenylpyrimidine) is an irreversible inhibitor of macrophage migration inhibitory factor (MIF)
TP1127L1 Nemifitide acetate(173240-15-8 free base) INN 00835 acetate 5-HT Receptor
Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. It is a peptide analog of melanocyte-inhibiting factor (MIF).
T60388 MIF098 Others
MIF098 is a macrophage migration inhibitory factor (MIF) antagonist.MIF098, inhibits pulmonary hypertension associated with SLE and inhibits pulmonary smooth muscle cell (PASMC) proliferation and migration.MIF098 may be ...
T6381 Amifostine trihydrate Ethyol trihydrate,WR2721,Amifostine Others , HIF/HIF Prolyl-Hydroxylase
Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.
T16074 Mifobate SR-202 PPAR
Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1].
T3383 Cimifugin Cimitin Others
Cimifugin (Cimitin) inhibits NO production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and for 1, 1-diphenyl-2-picrylhydrazyl free-radical scavenging activity in cell-free bioassay system.
T1492 Gemifloxacin mesylate LB-20304a,SB-265805S,Gemifloxacin mesylate DNA gyrase , Topoisomerase , Antibacterial
Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin Mesylate is the mesylate salt form of...
T23372 SMIFH2 Others
SMIFH2 is formin homology 2 (FH2) domains inhibitor.
T4497 Amifampridine 3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine Others
Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ...
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