k-ras — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5469	K-Ras-IN-1		Raf , Ras
	K-Ras-IN-1 is a K-Ras inhibitor.		Raf , Ras
T6555	K-Ras(G12C) inhibitor 12		Apoptosis , Raf , Ras
	K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).		Apoptosis , Raf , Ras
T6556	K-Ras(G12C) inhibitor 9		Raf
	K-Ras(G12C) inhibitor 9 is an allosteric inhibitor of oncogenic K-Ras(G12C).		Raf
T3725	K-Ras(G12C) Inhibitor 6		Raf
	K-Ras(G12C) inhibitor 6 is an irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 μM for 24 hours in vitro.		Raf
T11738	K-Ras G12C-IN-4		Ras
	K-Ras G12C-IN-4, is a potent Covalent Inhibitor of KRASG12C..		Ras
T8659	K-Ras-PDEδ-IN-1		PDE
	K-Ras-PDEδ-IN-1 is a potent inhibitor of competitive K-Ras-PDEδ.It binds to the farnesyl binding pocket of PDEδ(Kd of 8 nM).		PDE
T11735	K-Ras G12C-IN-1		Phosphatase
	K-Ras G12C-IN-1 is a novel and irreversible inhibitor of mutant K-ras G12C.		Phosphatase
T11737	K-Ras G12C-IN-3		Others
	Heterocyclic compounds as covalent inhibitors of G12C mutant K-Ras protein useful for treating cancers.K-Ras G12C-IN-3 is a novel and irreversible inhibitor of mutant K-ras G12C.		Others
T11736	K-Ras G12C-IN-2		Others
	K-Ras G12C-IN-2 is a covalent kras g12c inhibitor.		Others
T13844	PROTAC K-Ras Degrader-1		Ras
	PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.		Ras
T18059	K-Ras ligand-Linker Conjugate 6		Others
	K-Ras ligand-Linker Conjugate 6 is a chemical compound that combines a ligand for K-Ras recruiting moiety and a PROTAC linker. This compound can recruit E3 ligases, including VHL, CRBN, MDM2, and IAP. K-Ras ligand-Linker...		Others
T18054	K-Ras ligand-Linker Conjugate 1		Others
	K-Ras ligand-Linker Conjugate 1 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker, facilitating the recruitment of E3 ligases VHL, CRBN, MDM2, and IAP. It can be utilized in the synthesis of PRO...		Others
T18056	K-Ras ligand-Linker Conjugate 3		Others
	K-Ras ligand-Linker Conjugate 3 (Compound 001371) is a chemical compound that consists of a ligand for K-Ras recruiting moiety and a PROTAC linker, responsible for recruiting E3 ligases (e.g., VHL, CRBN, MDM2, and IAP). ...		Others
T18058	K-Ras ligand-Linker Conjugate 5		Others
	K-Ras ligand-Linker Conjugate 5 is a chemical compound that combines a ligand for the K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. T...		Others
T18055	K-Ras ligand-Linker Conjugate 2		Others
	K-Ras ligand-Linker Conjugate 2 is a chemical compound that includes a ligand for K-Ras and a PROTAC linker. This compound is capable of recruiting E3 ligases like VHL, CRBN, MDM2, and IAP. It is utilized in the synthesi...		Others
T18057	K-Ras ligand-Linker Conjugate 4		Others
	K-Ras ligand-Linker Conjugate 4 is a chemical compound that combines a ligand for K-Ras recruiting moiety with a PROTAC linker. This linker is responsible for recruiting E3 ligases such as VHL, CRBN, MDM2, and IAP. The c...		Others
T2678	LB42708		Transferase
	LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).		Transferase
T38050	CP-609754		Transferase
	CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombinant human H-Ras is 0.57 ng/mL and recombinant K-Ras is 46 n...		Transferase
T1931	6H05	K-Ras inhibitor	Raf , Ras
	6H05 (K-Ras inhibitor) is a selective, allosteric inhibitor of oncogenic mutant K-Ras(G12C).		Raf , Ras
TP2358	KRPEP-2D acetate		Raf
	KRPEP-2D acetate was identified as a K-Ras(G12D) selective inhibitory peptide against the G12D mutant of K-Ras, which is a key member of the Ras protein family and an attractive cancer therapeutic target.		Raf