integrase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T60742	HIV-1 integrase inhibitor 8		HIV Protease
	HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].		HIV Protease
T11566	HIV-1 integrase inhibitor		Others
	Hiv-1 integrase inhibitor is an effective anti-HIV drug.		Others
T11568	HIV-1 integrase inhibitor 4		Others
	HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 3.7 nM).		Others
T11567	HIV-1 integrase inhibitor 3		Others
	HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor (IC50: 2.7 nM).		Others
T11565	HIV-1 integrase inhibitor 7		Others
	HIV-1 integrase inhibitor 7 is a potent HIV-1 integrase inhibitor (IC50: 33.3 nM).		Others
T62156	HIV-1 integrase inhibitor 9
	HIV-1 integrase inhibitor 9 (compound 8a) is a potent inhibitor of HIV-1 RNase H (IC50: 12.3 μM) and has antiviral effects.
T72162	HIV-1 integrase inhibitor 10
	HIV-1 Integrase Inhibitor 10, an orally active allosteric integrase inhibitor (ALLINI), effectively inhibits the NLRepRluc virus's viral outgrowth in MT-2 cells, exhibiting EC50 values of 3-5 nM. This compound is utilize...
T64096	Integrase-LEDGF/p75 allosteric inhibitor 1
	Integrase-LEDGF/p75 allosteric inhibitor 1 is an orally active integrase-LEDGF/p75 (IN-LEDGF/p75) allosteric inhibitor. It inhibits HIV-1 DNA integration and exhibits antiviral effects, acting on the HIV-1 recombinant mo...
T15483	LEDGIN6	HIV-1 integrase inhibitor 2	Others
	HIV-1 integrase inhibitor 2 is used for the treatment of human immunodeficiency virus (HIV) infection.		Others
T4182	Lavendustin B		Tyrosinase , transporter , HIV Protease
	Lavendustin B is a Tyrosine Kinase Inhibitor and an inhibitor of HIV-1 integrase (IN) interaction with its cognate cellular cofactor, lens epithelium-derived growth factor (LEDGF/p75).		Tyrosinase , transporter , HIV Protease
T4493	Bictegravir	GS-9883	HIV Protease
	Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase (IC50: 7.5 nM).		HIV Protease
T6420	BMS-707035		HIV Protease
	BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.		HIV Protease
T2239L	Raltegravir	MK-0518	HIV Protease , Integrase
	Raltegravir (MK-0518) is a pyrrolidinone derivative and HIV INTEGRASE INHIBITOR that is used in combination with other ANTI-HIV AGENTS for the treatment of HIV INFECTION.		HIV Protease , Integrase
T0753	Salicylanilide	WR10019,2-Hydroxybenzanilide	HIV Protease , Reverse Transcriptase
	Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.		HIV Protease , Reverse Transcriptase
TN2158	Robinetin	3,3',4',5',7-Pentahydroxyflavone	Anti-infection , HIV Protease , Antibacterial
	Robinetin (3,3',4',5',7-Pentahydroxyflavone) has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency.		Anti-infection , HIV Protease , Antibacterial
T2239	Raltegravir potassium	MK 0518 potassium salt,Raltegravir potassium salt	HIV Protease , Integrase
	Raltegravir potassium (MK 0518 potassium salt) salt(MK0518 potassium salt) is a potent integrase (IN) inhibitor, used to treat HIV infection.		HIV Protease , Integrase
T6198	Dolutegravir	S/GSK1349572,GSK1349572	HIV Protease
	Dolutegravir (GSK1349572) (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.		HIV Protease
T2329	Dolutegravir sodium	GSK1349572,GSK-1349572A	HIV Protease
	Dolutegravir sodium (GSK-1349572A) salt(DTG; GSK1349572) is an HIV integrase inhibitor(IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.		HIV Protease
T6098	Cabotegravir	GSK744,GSK-1265744,S/GSK1265744	HIV Protease
	Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (IC50: 3.0 nM).		HIV Protease
T2332	Elvitegravir	GS-9137,EVG,D06677,JTK-303	HIV Protease
	Elvitegravir (JTK-303) is a Human Immunodeficiency Virus Integrase Strand Transfer Inhibitor. The mechanism of action of elvitegravir is as an HIV Integrase Inhibitor, and Cytochrome P450 2C9 Inducer.		HIV Protease