Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 33.00 | |
100 mg | In stock | $ 47.00 | |
200 mg | In stock | $ 60.00 | |
500 mg | In stock | $ 95.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 50.00 |
Description | Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities. |
In vitro | Some salicylanilides and salicylamides could inhibit HIV virus by targeting of HIV-1 integrase or reverse transcriptase. Hepatitis C virus could be potentially afflicted by salicylanilides on the level of two enzymes – NS3 protease and NS5B RNA polymerase. Nitazoxanide is a nitrothiazole derivative of salicylamide useful for the treatment of protozoal and bacterial infections with an extended range of antiviral activity and innovative mechanism of action, especially against hepatitis and influenza viruses or rotaviruses. Nitazoxanide, its metabolite tizoxanide and their derivatives are a very promising stream in the development of new antiviral compounds.[1] Salicylanilides is potential virulence inhibitors attributable to a blockade of the type III secretion pathway. Many salicylanilide ester derivatives have been demonstrated an effective and promising treatment against pathogenic fungi and bacteria (especially against Gram-positive, tuberculous and atypical mycobacterial strains), including strains such as methicillinresistant Staphylococcus aureus and isoniazid-resistant mycobacteria which are resistant to one or more clinically used drugs.[2] |
Synonyms | WR10019, 2-Hydroxybenzanilide |
Molecular Weight | 213.23 |
Formula | C13H11NO2 |
CAS No. | 87-17-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 15 mg/mL (70.3 mM)
DMSO: 40 mg/mL (187.6 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Salicylanilide 87-17-2 Microbiology/Virology Proteases/Proteasome HIV Protease Reverse Transcriptase WR 10019 HIV Human immunodeficiency virus HIV Integrase WR10019 inhibit Inhibitor WR-10019 2-Hydroxybenzanilide inhibitor