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Search Result

Search Results for " irap "

Targets

Others

27

Compounds

3

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T10820L1 Ciraparantag acetate Ciraparantag acetate(1438492-26-2 Free base) Others
Ciraparantag acetate, an anticoagulant reversal agent, is a small molecule specifically designed to bind noncovalently by charge-charge interaction to unfractionated heparin and low-molecular-weight heparin. It shows bin...
T9497 Niraparib tosylate monohyrate PARP
Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting...
T12064 Niraparib (R-enantiomer) MK 4827 (R-enantiomer),Niraparib R-enantiomer PARP
Niraparib R-enantiomer (MK 4827 R-enantiomer) is an inhibitor of PARP1(IC50 of 2.4 nM).
T3231 Niraparib MK-4827 Apoptosis , Others , PARP
Niraparib (MK-4827) is a PARP inhibitor that selectively inhibits PARP1 and PARP2 (IC50=3.8/2.1 nM). Niraparib has antitumor activity, inhibits DNA damage repair, and induces apoptosis.
T1595 Nevirapine NSC 641530,BI-RG 587,NVP HIV Protease , Reverse Transcriptase
Nevirapine (NVP) is a benzodiazepine non-nucleoside reverse transcriptase inhibitor. In combination with other antiretroviral drugs, nevirapine reduces HIV viral loads and increases CD4 counts, thereby retarding or preve...
T3353 Niraparib hydrochloride MK-4827 hydrochloride,MK-4827 (hydrochloride) Apoptosis , Others , PARP
Niraparib hydrochloride (MK-4827 hydrochloride) is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. Niraparib hydrochloride inhibits PARP activity, enhancing the accumulation of...
T4434 Tirapazamine Tirazone,Win59075,SR4233,SR259075 Others
Tirapazamine (Win59075) is a potent cytotoxic agent under hypoxic conditions, can induce apoptosis by inducing breaks in single and double-stranded DNA, as well as chromosomal breaks. The compound sensitizes cells to oth...
T6892 Niraparib tosylate MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate Apoptosis , PARP
Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.
T71517 Nevirapine quinone methide
Nevirapine quinone methide is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.
T10820L Ciraparantag TFA PER977 TFA Others
Ciraparantag TFA is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anti...
T74084 28-Epirapamycin
28-Epirapamycin, an impurity of Rapamycin, serves as a potent and specific mTOR inhibitor, exhibiting an IC50 value of 0.1 nM in HEK293 cells [1].
T71524 Famiraprinium
Famiraprinium is a competitive antagonist at the GABA receptor site.
T12229 Niraparib metabolite M1 M1 metabolite of niraparib,Niraparib carboxylic acid metabolite M1 Others
Niraparib metabolite M1 is niraparib metabolite, niraparib is a novel poly(ADP-Ribose) polymerase (PARP) inhibitor.
T24820 Spiraprilat Spiraprilate,SCH-33861,SCH 33861,SCH33861
Spiraprilat is an ACE inhibitor. It also is an active metabolite of spirapril.
T70794 Nevirapine dimer
Nevirapine dimer is a non-nucleoside reverse transcriptase inhibitor (NNRTI).
T74717 12-Hydroxynevirapine
12-Hydroxynevirapine (12-hydroxy-NVP; 12-OH-NVP), a significant oxidative metabolite of Nevirapine—an antiviral drug used for HIV-1 infections known for potential idiosyncratic hepatotoxicity and skin rashes—undergoes bi...
T69796 Nevirapine hemihydrate
Nevirapine hemihydrate is a non-nucleoside reverse transcriptase inhibitor (NNRTI) studied for potential treatment of HIV-1 infection and AIDS.
T10820 Ciraparantag PER977 Others
Ciraparantag is an inhibitor of thrombin and factor Xa. Ciraparantag is a broad-spectrum reversal agent for anticoagulants, including unfractionated heparin, low-molecular-weight heparin, and certain direct oral anticoag...
T28981 Tivirapine R-86183,R86183,8-Cl-TIBO,R 86183
Tivirapine, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
T63425 Spirapril hydrochloride
Spirapril (SCH 33844) hydrochloride is a potent inhibitor of angiotensin-converting enzyme (ACE) and is an orally active prodrug of spiripril. Spirapril hydrochloride can be used to study hypertension and congestive hear...
T34696 Spirapril HCl BRN4277924,BRN-4277924,BRN 4277924,Spiraprilum,Spirapril,Espirapril
Spiropril is an ACE inhibitor antihypertensive drug, which belongs to the bicarboxyl group of ACE inhibitors and is used in the treatment of hypertension.
T68214 Famiraprinium chloride
Famiraprinium chloride is a competitive antagonist at the GABA receptor site.
T61278 Aminopeptidase-IN-1 Aminopeptidase
Aminopeptidase-IN-1 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 7.7 μM).Aminopeptidase-IN-1 can be used in studies of cognitive and memory disorders.
T15479 HFI-142 Others
HFI-142 is an inhibitor of insulin-regulated aminopeptidase (IRAP) (Ki: 2.01 μM).
T27160 DG026 DG 026,DG-026
DG026 is a IRAP inhibitor. DG026 ables to selectively downregulate IRAP-dependent cross-presentation by dendritic cells but leave ERAP1-dependent cross-presentation unaffected.
T32240 IVDE77 IVDE-77,IVDE 77
IVDE77 is the first Ang IV-analogue with the ability to abolish IRAP-availability completely at the cell surface in vitro.
T61258 HFI-419
HFI-419 is a potent inhibitor of insulin-regulated aminopeptidase (IRAP) with a K i value of 0.48 μM. It is utilized in research pertaining to cognitive and memory impairments, including Alzheimer's disease, brain trauma...

Compounds

Ciraparantag acetate
T10820L1
Synonym: Ciraparantag acetate(1438492-26-2 Free base)
Target: Others
Niraparib tosylate monohyrate
T9497
Synonym:
Target: PARP
Niraparib (R-enantiomer)
T12064
Synonym: MK 4827 (R-enantiomer),Niraparib R-enantiomer
Target: PARP
Niraparib
T3231
Synonym: MK-4827
Target: Apoptosis, Others, PARP
Nevirapine
T1595
Synonym: NSC 641530,BI-RG 587,NVP
Target: HIV Protease, Reverse Transcriptase
Niraparib hydrochloride
T3353
Synonym: MK-4827 hydrochloride,MK-4827 (hydrochloride)
Target: Apoptosis, Others, PARP
Tirapazamine
T4434
Synonym: Tirazone,Win59075,SR4233,SR259075
Target: Others
Niraparib tosylate
T6892
Synonym: MK-4827 (tosylate),MK 4827 tosylate,Niraparib (MK-4827) tosylate
Target: Apoptosis, PARP
Nevirapine quinone methide
T71517
Synonym:
Target:
Ciraparantag TFA
T10820L
Synonym: PER977 TFA
Target: Others
28-Epirapamycin
T74084
Synonym:
Target:
Famiraprinium
T71524
Synonym:
Target:
Niraparib metabolite M1
T12229
Synonym: M1 metabolite of niraparib,Niraparib carboxylic acid metabolite M1
Target: Others
Spiraprilat
T24820
Synonym: Spiraprilate,SCH-33861,SCH 33861,SCH33861
Target:
Nevirapine dimer
T70794
Synonym:
Target:
12-Hydroxynevirapine
T74717
Synonym:
Target:
Nevirapine hemihydrate
T69796
Synonym:
Target:
Ciraparantag
T10820
Synonym: PER977
Target: Others
Tivirapine
T28981
Synonym: R-86183,R86183,8-Cl-TIBO,R 86183
Target:
Spirapril hydrochloride
T63425
Synonym:
Target:
Spirapril HCl
T34696
Synonym: BRN4277924,BRN-4277924,BRN 4277924,Spiraprilum,Spirapril,Espirapril
Target:
Famiraprinium chloride
T68214
Synonym:
Target:
Aminopeptidase-IN-1
T61278
Synonym:
Target: Aminopeptidase
HFI-142
T15479
Synonym:
Target: Others
DG026
T27160
Synonym: DG 026,DG-026
Target:
IVDE77
T32240
Synonym: IVDE-77,IVDE 77
Target:
HFI-419
T61258
Synonym:
Target:

Recombinant Proteins

Species：
Human (2)
Mouse (1)
Expression System：
E. coli (2)
HEK293 Cells (1)
Tag：
Tag Free (2)
hFc (1)
Cat No. Product Name Species Expression System
TMPY-00853 IL-1RA Protein, Human, Recombinant Human E. coli
IL-1RA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.3 kDa and the accession number is P18510-1.
TMPJ-00909 IL-1RA Protein, Mouse, Recombinant Mouse E. coli
Interleukin-1 receptor antagonist protein (Il1rn), also known as IL-1ra, IRAP or IL1 inhibitor, is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1 alpha (IL1A) and int...
TMPY-00852 IL-1RA Protein, Human, Recombinant (hFc) Human HEK293 Cells
IL-1RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.8 kDa and the accession number is P18510-1.
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