Search Result

Search Results for " il-27 "

Targets

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T1813	VGX-1027	VGX1027,VGX 1027,GIT 27	IL Receptor , TNF , Interleukin
	VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.		IL Receptor , TNF , Interleukin
T0097	MRT67307	MRT67307 HCl	IκB/IKK , Autophagy
	Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy. MRT67307 prevents the phosphorylation of IRF3 and the production of IFN-β and increases toll-like receptor-induced IL-10 and IL-1ra secretion in macrophage...		IκB/IKK , Autophagy
T80568	Casdozokitug	SRF-388
	Casdozokitug (SRF-388) is an IgG1κ monoclonal antibody that specifically targets interleukin-27 (IL-27) [1].
T74971	Diamino lipid DAL4
	Diamino lipid DAL4 is novel lipid nanoparticles (LNPs) encapsulated with mRNAs encoding cytokines including IL-12 , IL-27 and GM-CSF . Diamino lipid DAL4 delivers mRNA to tumor cells to exert anti-tumor activity [1] .
T36998	7β,27-dihydroxy Cholesterol	7β,27-DHC,7β,27-dihydroxy Cholesterol
	7β,27-dihydroxy Cholesterol is an oxysterol and agonist of retinoic acid receptor-related orphan receptor γ (RORγ) and RORγt. [1] It activates RORγ- or RORγt-dependent signaling with EC50 values of 691 and 1,045 nM, res...
T79256	DPP-4-IN-8
	DPP-4-IN-8 (compound 27) is a potent and selective inhibitor of dipeptidyl peptidase 4 (DPP4), with an inhibition constant (Ki) of 0.96 μM. It inhibits the dipeptidase activity of DPP4 in both Caco-2 and HepG-2 cells and...
T62221	NLRP3-IN-8
	NLRP3-IN-8 (compound 27), an orally active NLRP3 inflammasome inhibitor, directly binds to its target with an IC50 of 1.23 μM for IL-1β inhibition. It demonstrates robust metabolic stability in liver microsomes (t1/2 = 1...
T81678	NF(N-Me)GA(N-Me)IL	Amylin (22-27) [NMeG24, NMeI26], human (IAPP)
	NF(N-Me)GA(N-Me)IL is a biologically active peptide, representing a modified segment (amino acids 22 to 27) of the human islet amyloid polypeptide (hIAPP) sequence NFGAIL. This modification includes N-methylations at G24...
T23028	MRT67307 HCl (1190378-57-4 free base)	MRT67307 HCl	Others
	MRT67307 is an inhibitor for TBK1, IKKε , MARK1-4 and NUAK1 with IC50 value of 19, 160, 27-52 and 230nM , respectively [1]. It is an inhibitor for ULK1and ULK2 with IC50 value of 45 and 38nM, respectively [2]. Also, it i...		Others
T36629	Givinostat
	Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF30...

Compounds

VGX-1027

T1813

Synonym: VGX1027,VGX 1027,GIT 27

Target: IL Receptor, TNF, Interleukin

MRT67307

T0097

Synonym: MRT67307 HCl

Target: IκB/IKK, Autophagy

7β,27-dihydroxy Cholesterol

T36998

Synonym: 7β,27-DHC,7β,27-dihydroxy Cholesterol

Synonym: Amylin (22-27) [NMeG24, NMeI26], human (IAPP)

Target:

MRT67307 HCl (1190378-57-4 free base)

T23028

Synonym: MRT67307 HCl

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-03153	IL-27 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	IL-27 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.5 kDa and the accession number is O35228&Q8K3I6.
TMPY-03142	IL-27 Protein, Human, Recombinant (His)	Human	CHO Cells
	IL-27 Protein, Human, Recombinant (His) is expressed in CHO mammalian cells with His tag. The predicted molecular weight is 56 kDa and the accession number is NP_005746.2&NP_663634.2.
TMPY-00856	TCCR Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	TCCR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 79 kDa and the accession number is Q6UWB1.
TMPJ-01210	IL-33 Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi...
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPY-06792	TCCR Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	TCCR Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 56.37 kDa and the accession number is AAC40121.1.
TMPY-05543	TCCR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	TCCR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.6 kDa and the accession number is AAC40121.1.
TMPK-00356	IL-27RA/TCCR Protein, Human, Recombinant (His)	Human	HEK293 Cells
	IL-27Ra (also known as TCCR and WSX1) as a gene whose expression can induce the transformation of hematopoietic cells. IL-27Ra (IL-27R) is a type I cytokine receptor that functions as the ligand binding component of the ...
TMPK-00163	IL-33 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are exp...
TMPJ-01409	CCL27 Protein, Human, Recombinant	Human	E. coli
	Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gonads, thymus, placenta and skin. CCL27 elicits its chemotact...
TMPY-04264	SF20 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	SF20 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.2 kDa and the accession number is Q969H8.
TMPY-00034	SF20 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	SF20 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is Q969H8.
TMPK-00334	IL-10R alpha/IL-10RA Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	IL-10R alpha/IL-10RA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession number is Q13651.
TMPK-00335	IL-10R alpha/IL-10RA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	IL-10R alpha/IL-10RA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27 kDa and the accession number is Q13651.
TMPJ-01237	IL-17D Protein, Human, Recombinant	Human	E. coli
	The Interleukin-17 family proteins, comprising six members (IL-17, IL-17B through IL-17F),are secreted, structurally related proteins that share a conserved cysteine-knot fold near the C-terminus, but have considerable s...