hacat — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3866	Macelignan	Anwuligan,(+)-Anwulignan	Others , COX
	Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.		Others , COX
T50005	Sertaconazole		Antifungal
	Sertaconazole is a broad-spectrum antifungal.		Antifungal
T5669	Citric acid monohydrate		Others
	Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients a...		Others
T5S0636	Citric acid	Citro,Citretten	Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
	1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
T6665	Sertaconazole nitrate	FI-7045,Ginedermofix,FI7056,Ertaczo	Antibiotic , Antifungal
	Sertaconazole nitrate (FI-7045), a topical broad-spectrum antifungal, is developed to supply an additional agent for the treatment of superficial cutaneous and mucosal infections.		Antibiotic , Antifungal
T4939	Indole-3-pyruvic acid	3-(3-Indolyl)-2-oxopropanoic acid	Others
	Indole-3-pyruvic acid (3-(3-Indolyl)-2-oxopropanoic acid) is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmenta...		Others
T7769	Nonapeptide-1	Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-,Melanostatine™ 5	Others
	Nonapeptide-1 (Melanostatine™ 5) can inhibit the synthesis of melanin, which makes it of interest for treating certain skin conditions.		Others
TN2077	(+/-)-Pinocembrin	NSC 43318,(±)-5,7-Dihydroxyflavanone	GPR , Others
	(+/-)-Pinocembrin (NSC-43318), a natural product from axillary pines, is a GPR120 ligand that promotes wound healing in the HaCaT cell line.		GPR , Others
TN4987	Semialactone		Others
	Semialactone shows inhibitory activities on human acyl-CoA:cholesterol acyltransferase(hACAT)1 with IC50 values of 79.1 uM and on human hACAT2 with IC50 values of 76.9 uM, it may be effective in the prevention and treatm...		Others
T73580	8A8		NO Synthase
	8A8 is a potent NO inhibitor with proinflammatory factor properties, exhibiting an IC50 of 4.7 μM. Additionally, it significantly inhibits LPS-induced proliferation in HaCat cells [1].		NO Synthase
T35671	Salazinic Acid
	Salazinic acid is a depsidone lichen metabolite that has been found in P. sulcata.1 It is active against B. cereus, B. subtilis, S. aureus, P. aeruginosa, S. typhimurium, C. albicans, and A. niger in vitro (MICs = 3.9-30...
T61996	Antiproliferative agent-6
	Antiproliferative agent-6 (compound 8a) is a potent antitumor compound. Antiproliferative agent-6 shows antiproliferative activity. Antiproliferative agent-6 inhibits cancer cell lines HCT116, MCF-7, H460 and non-tumor a...
T83744	Tiger17 TFA	H-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2
	Tiger17, a cyclic peptide derivative of tigerinin-RC1 and tigerinin-RC2—antimicrobial peptides from the crab-eating frog (F. cancrivora) skin secretions—enhances HaCaT keratinocytes and human skin fibroblasts proliferati...
T75535	5-epi-Arvestonate A
	5-epi-Arvestonate A, a sesquiterpenoid extracted from Seriphidium transiliense whole plants, enhances melanogenic production by stimulating MITF and tyrosinase family gene transcription. Additionally, it suppresses IFN-γ...
TN5288	Ergosterol peroxide glucoside	Ergosterol peroxide 3-O-β-D-glucopyranoside
	Ergosterol peroxide exhibits anti-cancer, amoebicidal, anticomplementary, antibacterial, antiviral, anti-oxdiant, and anti-melanogenic activities. Ergosterol peroxide could as an anti-atherosclerosis agent, it exhibits h...
T81261	ROCK2-IN-7		ROCK
	ROCK2 inhibitor is a chemical compound associated with the therapeutic management of psoriasis. It exhibits its efficacy in targeting ROCK2 enzymes within HaCaT cells and has demonstrated beneficial effects in a psoriasi...		ROCK
T4620	Siramesine	Lu 28-179	Sigma receptor
	Siramesine (Lu 28-179)(Lu 28-179) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of cancer cells and to exhibit a potent anticancer activity in vivo.lysosome-destabilizing agent siram...		Sigma receptor
T83735	Pap12-6 TFA
	Pap12-6, an antibacterial peptide originating from the first twelve N-terminal amino acids of papiliocin found in P. xuthus larvae, exhibits activity against a range of eight Gram-negative bacteria (e.g., E. coli, P. aer...