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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T24055 | FAUC 213 | FAUC213,FAUC-213 | Dopamine Receptor |
FAUC 213 is a selective full antagonist of the dopamine D4 receptor. | |||
T1684 | Nitisinone | NTBC,SC0735,Nitisone | Others , Reactive Oxygen Species |
Nitisinone (SC0735)(SC0735) is an enzyme 4-hydroxyphenylpyruvate dioxygenase inhibitor. | |||
T37197 | 5-HT1A modulator 2 hydrochloride | 5-HT Receptor | |
5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT , is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding[1]. [1]. Naiman, N.,et al. 2-(Alkylamino)tetralin derivatives: interaction with 5-HT1A serotoni... | |||
T10168 | 5-HT1A modulator 1 | 5-HT1Amodulator1 | Phospholipase , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM). | |||
T62843 | 5-HT1A antagonist 1 | ||
5-HT1A antagonist 1 (compound 6f) is a potent and selective 5-HT1Areceptor antagonist (Ki: 35 nM). 5-HT1A antagonist 1 can be used in the study of central nervous system disorders. | |||
T27558 | HT1042 | HT 1042,HT-1042 | |
HT1042 is an inhibitor of the β5i component of the 20S proteasome complex, it is used to aid in the treatment of inflammatory diseases, autoimmune and hematologic malignancies. | |||
T0203 | Sumatriptan succinate | GR 43175 | 5-HT Receptor |
Sumatriptan succinate (GR 43175), a serotonin1 (5-HT1) receptor agonist, is used in the acute treatment of a migraine headache. | |||
T8666 | Naratriptan | 5-HT Receptor | |
Naratriptan is a selective agonist of 5-HT1 receptor and is is used for the treatment of migraine headaches. | |||
T12207 | NEO 376 | SPI-376 | Dopamine Receptor , 5-HT Receptor , GABA Receptor |
NEO 376 (SPI-376) is a selective 5-HT1 receptor, GABA receptor and dopamine receptor modulator, showing anti-psychotic actively. | |||
T10872L | CP 96021 | 5-HT Receptor | |
CP 96021 is a group of 5-HT1 receptors and 5-HT2 receptors antagonists that have anti-inflammatory properties and are non-non-self anti-ulcer compounds for the treatment of gastrointestinal tract and respiratory asthma. | |||
T22534 | 8-Hydroxy-DPAT hydrobromide | 8-OH-DPAT hydrobromide | 5-HT Receptor |
8-Hydroxy-DPAT hydrobromide (8-OH-DPAT hydrobromide) (8-OH-DPAT hydrobromide) is a potent and selective 5-HT1A agonist with a pIC50 of 8.19. 8-Hydroxy-DPAT hydrobromide has a selectivity of almost 1000 fold for a subtype... | |||
T23382 | Spiroxatrine | R 5188 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Spiroxatrine (R 5188) is a selective and potent 5-HT1α and α2-adrenergic dual antagonist with sedative activity and inhibitory effects on 5-HT1α, 5-HT1 β, 5-HT2, and dopamine receptors.Spiroxatrine may be used in the stu... | |||
T21385 | Cinitapride | Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove | 5-HT Receptor |
Cinitapride (Blaston) is a gastroprokinetic agent. It slows the actions of the muscles to reduce the symptoms of conditions such as acid reflux, delayed gastric emptying, and ulcer dyspepsia. Cinitapride acts as an antag... | |||
T4978 | Sarpogrelate hydrochloride | MCI-9042 | 5-HT Receptor |
Sarpogrelate hydrochloride (MCI-9042) , a selective 5-HT2 antagonist, has been widely used as an anti-platelet agent for the treatment of PAD. Target: 5-HT2 Recepter Sarpogrelate is a drug which acts as an antagonist at ... | |||
T1512 | Rizatriptan benzoate | MK-462 Benzoate | 5-HT Receptor |
Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine headaches. | |||
T0162 | Quetiapine | ICI204636,Quetiapin | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor |
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antago... | |||
T6602 | Naratriptan hydrochloride | Naratriptan HCl,Amerge,Naramig,GR-85548A hydrochloride | 5-HT Receptor |
Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydroc... | |||
T23405 | Sumatriptan | Others | |
Sumatriptan succinate is a selective 5-HT1 receptor agonist with specificity towards 5-HT1D, 5-HT1B, and 5-HT1A. | |||
T68176 | Isamoltane | ||
Isamoltane is a serotonin 5-HT1 Receptor Antagonist | |||
T4375 | Methiothepin maleate | Metitepine | 5-HT Receptor |
Methiothepin maleate (Metitepine) is a 5-HT1, 5-HT6, 5-HT7 serotonin receptor antagonist, which blocks serotonin autoreceptors. |