dab — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T30098	Aplindore Fumarate	Aplindore,DAB-452 Fumarate,DAB-452	Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
	Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors, and low affinity for dopamine D4, 5-hydroxytryptophan (5-H...		Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
T7595	L-DABA	L-2,4-Diaminobutyric acid,L-DAB HBR	GABA Receptor , Endogenous Metabolite
	L-DABA (L-2,4-Diaminobutyric acid) is an inhibitor of GABA transaminase (IC50 > 500 μM).		GABA Receptor , Endogenous Metabolite
T25197	Bz-Dab(nbd)-awfpp-nle-NH2	Bz-Dab(nbd)-ala-trp-phe-pro-pro-nle-NH2
	Bz-Dab(nbd)-ala-trp-phe-pro-pro-nle-NH2 is a fluorescent NK2 antagonist.
T21353	Fmoc-Dab(Boc)-OH
	Fmoc-Dab(Boc)-OH is a chemical intermediate used for chemical synthesis.
T82620	DAB tetrahydrochloride dihydrate	3,3-Diaminobenzidine tetrahydrochloride dihydrate
	3,3-Diaminobenzidine tetrahydrochloride dehydrate, commonly employed as a staining agent in histochemical (HC) and immunohistochemical (IHC) applications, facilitates peroxisomal staining and the detection of mitochondri...
TP2007	Lei-Dab7	Lei-Dab 7
	High affinity, selective KCa2.2 (SK2) channel blocker (Kd = 3.8 nM). Exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, IK, Kv and Kir2.1. Increases theta-burst responses and increases LTP in rat hipp...
T81713	N-4′-(p-Trifluoromethylphenyl)butyl-DAB
	N-4′-(p-Trifluoromethylphenyl)butyl-DAB (compound 5g) acts as an agonist for lysosomal acid α-glucosidase (GAA). It dose-dependently enhances intracellular GAA activities in Pompe disease patient fibroblasts harboring th...
T23797	Bis(diazoacetyl)butane	1,4-Bis-diazoacetylbutane,Supermutagen,1,4-Bis(diazoacetyl)butane,DAB (mutagen)
	Bis(diazoacetyl)butane is a mutagen and traditionally related to radio-mimetic chemical mutagens due to the similarity of appearance of mutagenic action of this mutagen and physical mutagens. It also has anti-tumor and c...
T70071	SLM6031434 (free base)
	SLM6031434 (free base) is an inhibitor of sphingosine kinase type 2 (SphK2). It consists of pedant 1-guanidino-2-phenyloxadiazolylpyrrolidine group.
T19270	DTPA-DAB2		Others
	DAB2-DTPA is a conjugate of DTPA and two DABs used in the photooxidation experiment.		Others
T18962	Dabcyl acid, SE	Dabcyl, SE	Others
	Dabcyl acid, SE (Dabcyl, SE) is the amino-reactive form of Dabcyl acid and used to prepare a variety of FRET-based probes that contain Dabcyl acid.		Others
T31175	Dabelotine	UNII-6RY56RB98P	Adrenergic Receptor
	Dabelotine (UNII-6RY56RB98P) is an adrenergic agonist used in the study of dementia.		Adrenergic Receptor
T8474	Dabrafenib Mesylate	GSK 2118436B,GSK2118436 Mesylate	Raf
	Dabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E and c-Raf, respectively).		Raf
T18964	Dabsyl chloride	DABS-Cl	Others
	Dabsyl chloride (DABS-Cl) is an amine derivatizing agent and able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm.		Others
T77795	L-DABA hydrobromide	L-2,4-Diaminobutyric acid hydrobromide	Others , Endogenous Metabolite
	L-DABA hydrobromide (L-2,4-Diaminobutyric acid hydrobromide) is a potent GABA transaminase inhibitor with antitumor and anticonvulsant activity for the study of neurological disorders.		Others , Endogenous Metabolite
T10951	Dabigatran ethyl ester hydrochloride		Others , Thrombin
	Dabigatran ethyl ester hydrochloride is an effective inhibitor of ribosyl dihydronicotinic acid amide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and is a thrombin inhibitor.		Others , Thrombin
T10952	Dabuzalgron	Ro 115-1240	Apoptosis , Adrenergic Receptor
	Dabuzalgron (Ro 115-1240) is an orally active selective alpha-1A adrenergic receptor agonist used to treat urinary incontinence. Dabuzaron prevents cardiotoxicity caused by doxorubicin by maintaining mitochondrial functi...		Apoptosis , Adrenergic Receptor
T5133	Dabigatran Etexilate Mesylate	BIBR 1048MS,Dabigatran etexilate methanesulfonate	Thrombin
	Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI, Ki: 4.5 nM).		Thrombin
T1903	Dabrafenib	GSK2118436A,GSK2118436	Raf
	Dabrafenib (GSK2118436A) is a Raf inhibitor that inhibits C-Raf and B-RafV600E (IC50=5/0.6 nM) and is ATP-competitive. Dabrafenib exhibits antitumor activity for the treatment of B-RafV600E-mutated melanoma.		Raf
T5114	Pyridaben		Calcium Channel , Parasite
	Pyridaben is a METI acaricide that inhibits mitochondrial electron transport at complex I (METI; Ki = 0.36 nmol/mg protein in rat brain mitochondria).		Calcium Channel , Parasite