20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60917 | Dopamine D4 receptor antagonist-1 | ||
Dopamine D4 receptor antagonist-1 can be used in schizophrenia study. Dopamine D4 receptor antagonist-1 is a selective antagonist of Dopamine D4 receptor (DRD4). The Ki value of Dopamine D4 receptor antagonist-1 for Hd4.... | |||
T22019 | ABT 724 trihydrochloride | Dopamine Receptor | |
ABT 724 trihydrochloride is an effective and selective agonist of the D4 receptor (EC50 = 12.4 nM, 14.3 nM, and 23.2 nM for human, rat and ferret, respectively). ABT-724 trihydrochloride can be used in erectile dysfuncti... | |||
T7834 | ABT-724 | Dopamine Receptor | |
ABT-724 is an agonist of dopamine D4 receptor(EC50: 12.4 nM) | |||
T22904 | L-745870 trihydrochloride | L-745,870 trihydrochloride | Dopamine Receptor , Sigma receptor , 5-HT Receptor , Adrenergic Receptor |
L-745870 trihydrochloride is a highly potent and selective D4 dopamine receptor antagonist. | |||
T12383 | PD 168568 dihydrochloride | PD 168568 (dihydrochloride) | Dopamine Receptor |
PD 168568 dihydrochloride (PD 168568 (dihydrochloride)) is an orally active and selective antagonist of D4 dopamine receptor(Ki of 8.8 nM). | |||
T12761 | Ro 10-5824 dihydrochloride | Dopamine Receptor | |
Ro 10-5824 dihydrochloride is a selective agonist of dopamine D4 receptor partial, (Ki of 5.2 nM). | |||
T15270 | Fananserin | RP 62203 | Dopamine Receptor , 5-HT Receptor |
Fananserin is an effective, selective and oral active antagonist of 5-HT2 (Ki = 0.37 nM for the rat 5-HT2A). Fananserin is an antagonist of human D4 receptor (Ki = 2.93 nM). | |||
T10213 | A-437203 | ABT-925,A37203,Lu201640 | Dopamine Receptor |
A-437203 (Lu201640) is A kind of based on 1 h - pyrimidin - 2 - one sca ff old, selective, new powerful d3 receptor antagonist, on D2, d3, and D4 receptor, Ki value 71, respectively 1.6 and 6220 nM. | |||
T15686 | L-741626 | 3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole | Dopamine Receptor |
L-741626 (3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole) is a selective antagonist of D2 dopamine receptor (Ki: 2.4, 100, and 220 nM for human D2, D3 and D4 receptors respectively). | |||
T27979 | Masilukast | ICI-D-3523,ZD-3523,ICI D-3523,MCC-847,SA-09012,D-3523 | Leukotriene Receptor |
Masilukast(MCC-847) is an oral leukotriene D4 (LTD4) receptor antagonist for the study of diseases associated with inflammation. | |||
T5047 | PD-168077 maleate | Dopamine Receptor | |
PD-168077 maleate is a selective agonist of dopamine D4 receptor(Ki : 9 nM) | |||
T11799 | L-745870 hydrochloride | Dopamine Receptor | |
L-745870 hydrochloride has excellent brain penetration. L-745870 hydrochloride is a high-affinity, selective and orally active human dopamine D4 receptor antagonist with a Ki of 0.43 nM, and considerably weaker D2 recept... | |||
T27060 | CP-226269 | CP 226269,CP226269 | Dopamine Receptor |
CP-226269 is a potent dopamine D4 receptor agonist that regulates calcium flux and has an EC50 value of 32.0 nM. CP 226269 can be used to study neurological disorders such as schizophrenia. | |||
T23066 | NGD 94-1 | Dopamine Receptor | |
NGD 94-1 is a selective D4 receptor antagonist with an affinity of 3 nM for the D4 receptor and greater than 2 pM for the D1, D2, D3, and D5 receptors.NGD 94-1 can be used in the study of cognitive disorders and other ps... | |||
T12480 | Pipamperone | Floropipamide,McN-JR 3345,R 3345 | Others , Dopamine Receptor , 5-HT Receptor |
Pipamperone (McN-JR 3345) binds 5-HT2A closely as receptor. | |||
T5397 | A-381393 | Dopamine Receptor | |
A-381393 is a selective and brain penetrate dopamine D4 receptor antagonist (Kis: 1.9/1.5/1.6 nM for human dopamine D4.2/D4.4/D4.7 receptor). | |||
T24055 | FAUC 213 | FAUC213,FAUC-213 | Dopamine Receptor |
FAUC 213 is a selective full antagonist of the dopamine D4 receptor. | |||
T5158 | N-Desmethylclozapine | Desmethylclozapine,Normethylclozapine,Norclozapine | Virus Protease , Dopamine Receptor , 5-HT Receptor , Opioid Receptor , AChR , Drug Metabolite |
N-Desmethylclozapine (Desmethylclozapine) is an antagonist of serotonin (5-HT) receptor subtype 5-HT2C (IC50: 7.1 nM). It also is an antagonist at dopamine D4 receptors, an agonist at δ-opioid receptors. | |||
T30098 | Aplindore Fumarate | Aplindore,DAB-452 Fumarate,DAB-452 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Aplindore Fumarate (DAB-452) is a small molecule dopamine D2 receptor partial agonist.Aplindore Fumarate exhibits high affinity for dopamine D2 and D3 receptors, and low affinity for dopamine D4, 5-hydroxytryptophan (5-H... | |||
T31602 | Ecopipam | Sch-39166,UNII-0X748O646K,Sch 39166 | Dopamine Receptor |
Ecopipam (UNII-0X748O646K) is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam shows more than 40-flod selectivity over D2, D4, 5-HT, and ... |