corticosterone — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T0948L	Corticosterone	17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,Corticosterone (From plants)	Glucocorticoid Receptor , Endogenous Metabolite
	Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stres...		Glucocorticoid Receptor , Endogenous Metabolite
T22708	Darglitazone	CP-86325	PPAR
	Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism.		PPAR
TN6864	Prosaikogenin F	(2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3,4,5-triol	Others
	Prosaikogenin F ((2R,3R,4S,5R,6R)-2-{[(1S,2R,4S,5R,8R,9S,10R,13S,14R,17S,18R)-2-hydroxy-9-(hydroxymethyl)-4,5,9,13,20,20-hexamethyl-24-oxahexacyclo[15.5.2.01,1?.0?,1?.0?,1?.0?,13]tetracos-15-en-10-yl]oxy}-6-methyloxane-3...		Others
T20302	Deoxycorticosterone	Desoxycorticosterone,Desoxycorticosteronum,Desoxycortone	Endogenous Metabolite
	Deoxycorticosterone (Desoxycortone) is a steroid metabolite produced by the adrenal gland. Deoxycorticosterone is an aldosterone precursor and possesses mineralocorticoid activity.		Endogenous Metabolite
T3033	Deoxycorticosterone acetate	DOC acetate,Cortexone acetate,11-Deoxycorticosterone acetate	Glucocorticoid Receptor , Endogenous Metabolite , Adrenergic Receptor
	Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid.
T19614	18-Hydroxycorticosterone		Others
	18-Hydroxycorticosterone is a corticosteroid and corticosterone derivative, which can lead to serious electrolyte imbalances.		Others
T81010	Tetrahydro-11-dehydrocorticosterone
	Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].
T68877	Tetrahydrocorticosterone
	Tetrahydrocorticosterone (THB) is a glucocorticoid (GC) that has anti-inflammatory functions. For instance, 5α THB inhibits inflammatory actions by binding to GC receptor. HPLC studies in rat brains have reported that te...
T37725	Tetrahydrodeoxycorticosterone	21-Hydroxypregnanolone,Tetrahydro-11-deoxycorticosterone	GABA Receptor
	Tetrahydrodeoxycorticosterone(Tetrahydro-11-deoxycorticosterone) is a potent GABAA receptor orthosteric modulator (PAM) with neuroprotective activity that selectively inhibits neurosteroid-mediated enhancement of GABA-in...		GABA Receptor
TC0008	Desoxycorticosterone pivalate	DOCP	Others
	Deoxycorticosterone (DOCP) is a mineralocorticoid and is an analog of deoxycorticosterone. Deoxycorticosterone pivalate is used in the treatment of canine low adrenal cortex hormones.		Others
T68808	11-Dehydrocorticosterone
	11-Dehydrocorticosterone is an endogenous mineralocorticoid. It increases Na+/K+-ATPase mRNA expression in vascular smooth muscle cells and inhibits aldosterone action in B. marinus toad bladder tissue in a concentration...
T36926L	Neuropeptide SF (human) aceate		Others
	Neuropeptide SF (human) aceate is a neuropeptide that augmented paraventricular CRH release and increased ACTH and corticosterone levels in the plasma.		Others
TP2082L	D[Cha4]-AVP acetate(500170-27-4 free base)		Vasopressin Receptor
	d[Cha4]-AVP acetate is a potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secre...		Vasopressin Receptor
TN1601	Effusol		Caspase
	Effusol is a natural product, exhibits potent scavenging activity for DPPH and ABTS radicals(IC50 values of 79 μM and 2.73 μM, respectively). Effusol rescues CA1 LTP attenuated by corticosterone, defending the hippocampa...		Caspase
T13489	21-Hydroxypregnenolone		Others
	21-Hydroxypregnenolone is an essential intermediate in corticosterone synthesis.		Others
T83268	6-Epiagarotetrol
	6-Epiagarotetrol, a neuroprotective agent derived from Aquilaria sinensis, exhibits protective effects against corticosterone-induced damage in PC12 cells [1].
TP2082	D[Cha4]-AVP
	Potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secretion and exhibits negligi...
TCA2511	11Beta-hydroxyprogesterone		Sodium Channel
	The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro and can confer mineralocorticoid activity on corticosterone...		Sodium Channel
T76646	Acetyl-ACTH (7-24) (human, bovine, rat)
	Acetyl-ACTH (7-24) (human, bovine, rat) effectively inhibits the secretion of corticosterone and aldosterone triggered by ACTH stimulation [1].
T21466	MK-212	MK 212,MK212
	MK-212 is a 5HT2C-receptor agonist. Intraperitoneal injection of MK-212 in 0.5 and 1.0 mg/kg increased the blood level of corticosterone in mice and reduced their motor activity. In 0.1 and 0.2 mg/kg, the agonist reduced...