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d[Cha4]-AVP acetate(500170-27-4 free base)

Catalog No. TP2082L CAS TP2082L

d[Cha4]-AVP acetate is a potent and selective human vasopressin V1B receptor agonist (Ki values are 1.2, 151, 240 and 750 nM for V1B, V1A, Oxytocin and V2 receptors respectively). Stimulates ACTH and corticosterone secretion and exhibits negligible vasopressor activity in vivo.

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d[Cha4]-AVP acetate(500170-27-4 free base), CAS TP2082L

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Molecular Weight	1154.37
Formula	C52H75N13O13S2
CAS No.	TP2082L

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Derick et al (2002) [1-Deamino-4-cyclohexylalanine] arginine vasopressin: a potent and specific agonist for vasopressin V1b receptors. Endocrinology 143 4655 PMID: 2. Cheng et al (2004) Design of potent and selective agonists for the human vasopressin V1b receptor based on modifications of [deamino-cys1]arginine vasopressin at position 4. J.Med.Chem. 47 2375 PMID: 3. Pena et al (2007) Design and synthesis of the frist selective agonists for the rat vasopressin V1b receptor: based on modifications of deamino-[cys1]arginine vasopressin at positions 4 and 8. J.Med.Chem. 50 835 PMID:

Related compound libraries

This product is contained In the following compound libraries：

Peptide Compound Library Bioactive Compound Library

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d[Leu4,Lys8]-VP acetate Argipressin LIXIVAPTAN Mozavaptan Desmopressin acetate (16679-58-6 free base) Desmopressin Atosiban Fuscoside

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Keywords

d[Cha4]-AVP acetate(500170-27-4 free base) TP2082L GPCR/G Protein Vasopressin Receptor d[Cha4]AVP acetate(500170274 free base) d[Cha4] AVP acetate(500170 27 4 free base) d[Cha-4]-AVP acetate(500170-27-4 free base) Inhibitor inhibitor inhibit

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