carboplatin — TargetMol Chemicals

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Search Results for " carboplatin "

Compounds

Cat No.	Product Name	Synonyms	Targets
T1058	Carboplatin	NSC 241240,CBDCA,JM-8	DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
	Carboplatin (JM-8) is a cisplatin derivative, a DNA synthesis inhibitor. Carboplatin binds to DNA, inhibits replication and transcription, and induces cell death. Carboplatin has antitumor activity.		DNA Alkylator/Crosslinker , DNA/RNA Synthesis , Autophagy
T68065	Enloplatin
	Enloplatin is a carboplatin analog that has a partial role in advanced ovarian cancer.
T77401	Bavituximab	Anti-PS MAb 3G4	Others
	Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a monoclonal antibody against phosphatidylserine (PS) with vascular targeting and immunomodulatory properties. It can reactivate anti-tumor immunity to ...		Others
T27307	Fasnall		Fatty Acid Synthase
	Fasnall is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall shows potent anti-tumor activity in the MMTV-Neu model of HER2(+) breast cancer, particularly when combined with carboplatin.		Fatty Acid Synthase
T27307L	Fasnall HCl	Fasnall HCl（929978-58-5 Free base）	Fatty Acid Synthase
	Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall HCl also shows potent anti-tumor activity in the MMTV-Neu model of HER2(+) breast cancer, particularly when combined with c...		Fatty Acid Synthase
T9864	Debio-0123	WEE1-IN-5	Wee1
	Debio-0123 (WEE1-IN-5) is a potent, orally available and highly specific WEE1 inhibitor with an IC 50 in the low nanomolar range. Debio-0123 inhibits phospho-CDC2 which translated into an increase in DNA damage and prema...		Wee1
T38765	UBE2T/FANCL-IN-1	UBE2T/FANCL-IN-1
	UBE2T/FANCL-IN-1 is a highly effective inhibitor of UBE2T/FANCL-mediated FANCD2 monoubiquitylation. It greatly enhances the sensitivity of cells to Carboplatin, a DNA cross-linking agent.
T35647	4-oxo-27-TBDMS Withaferin A
	4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/...
T27790	Labradimil	RMP-7,ALK-01-040,Receptor-mediated permeabiliser-7,DRG0182,DRG 0182,DRG-0182
	Labradimil is a bradykinin B2 receptor agonist. Labradimil increases the permeability of human brain microvascular endothelial cell monolayers. Labradimil enhances delivery of hydrophilic chemotherapeutics and increases ...
T36893	4-oxo Withaferin A
	4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1...
T28398	Phenanthriplatin	cis-[Pt(NH3)2-(phenanthridine)Cl]NO3
	Phenanthriplatin, also known as cis-[Pt(NH3)2-(phenanthridine)Cl]NO3, is a new drug candidate. It belongs to a family of platinum(II)-based agents which includes cisplatin, oxaliplatin and carboplatin. Phenanthriplatin A...