Search Result

Search Results for " ct2 "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T4428	CCT241736		FLT , Aurora Kinase
	CCT241736 is an orally bioavailable dual FLT3/Aurora kinase inhibitor that also inhibits clinically relevant FLT3-resistant mutants including FLT3-ITD and FLT3, CCT241736, an advanced analog of CCT137690, is a preclinica...		FLT , Aurora Kinase
T7080	CCT245737	SRA737	Chk
	CCT245737 (SRA737) is an orally active and selective Chk1 inhibitor (IC50: 1.3 nM); CCT245737 shows much less activity against Chk2 (IC50: 2440 nM).		Chk
T14907	CCT251545		Wnt/beta-catenin
	CCT251545 is an potent and oral-bioavailable WNT signaling inhibitor(IC50 of 5 nM in 7dF3 cells).		Wnt/beta-catenin
T10718L	CCT241533 hydrochloride		Chk
	CCT241533 hydrochloride is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).		Chk
T9638	CCT241161		Raf
	CCT241161 is an orally active pan-RAF inhibitor, with IC50 values of 3, 6, 10, 15, and 30 nM for LCK, CRAF, SRC, V600E-BRAF, and BRAF, respectively. It displays significant activity against BRAF and NRAS mutant melanomas...		Raf
T14904	CCT244747		Chk
	CCT244747 is a CHK1 inhibitor (IC50: 7.7 nM) and also abrogates G2 checkpoint (IC50: 29 nM).		Chk
T36704	CCT241533 dihydrochloride	CCT 241533 dihydrochloride
	Potent Chk2 inhibitor (IC50 = 3 nM). Shows >63-fold selectivity for Chk1 over Chk2 and a panel of 84 other kinases. Inhibits Chk2 activation in response to etoposide-induced DNA damage in HT29 cells. Blocks ionizing radi...
T10718	CCT241533		Chk
	CCT241533 is an effective and selective ATP competitive inhibitor of CHK2 (Ki: 1.16 nM; IC50: 3 nM).		Chk
T71353	CCT239065
	CCT239065 is a novel, selective, and efficacious nanomolar pyridopyrazinone V600EBRAF and LCK inhibitor.
T32136	ICT2700	de OH CPI MI,deOHCPIMI,de-OH-CPI-MI,ICT 2700,ICT-2700
	ICT2700 is a potent cytotoxin selectively by CYP1A1 as a tumor-selective treatment for human bladder cancers.
T70553	CCT245737(S)
	CCT245737(S) is a highly selective oral checkpoint kinase 1 (CHK1) inhibitor.
T14905	CCT251236		HSP
	CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen. It inhibits HSF1-mediated HSP72 induction (IC50: 19 nM).		HSP
T22633	CCT251545 analogue, Compound 51		Others
	CCT251545 analog is a potent and selective CDK8/19 inhibitor (IC50: 5.1 nM and 5.6 nM, respectively). Mediator complex-associated kinases CDK8 and CDK19 are involved in the regulation of multiple transcription pathways. ...		Others
T62775	CCT245232
	CCT245232 is a potent inhibitor of heat-stimulated factor 1 (HSF1). CCT245232 has the potential to be used in studies of proliferative diseases such as cancer.
T14906	CCT251455		Kinesin
	CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).		Kinesin
T63830	Anticancer agent 76
	Anticancer agent 76 (Compound CT2-3) is an anti-cancer agent that significantly inhibits proliferation, induces cell cycle arrest, ROS production and apoptosis in human NSCLC cells.

Compounds

CCT241736

T4428

Synonym:

Target: FLT, Aurora Kinase

Target: Wnt/beta-catenin

CCT241533 hydrochloride

CCT241533 dihydrochloride

T36704

Synonym: CCT 241533 dihydrochloride

Synonym: de OH CPI MI,deOHCPIMI,de-OH-CPI-MI,ICT 2700,ICT-2700

CCT251545 analogue, Compound 51

Cat No.	Product Name	Synonyms	Targets
T4702	(3-Carboxypropyl)trimethylammonium chloride	γ-Butyrobetaine hydrochloride,(3-Carboxypropyl)trimethylammonium chlor	Endogenous Metabolite
	(3-Carboxypropyl)trimethylammonium chloride ((3-Carboxypropyl)trimethylammonium chlor) is a synthetic carnitine related compound used as a transporter substrate in the cloning and sequencing of human carnitine transporte...		Endogenous Metabolite

Natural Products

(3-Carboxypropyl)trimethylammonium chloride

T4702

Synonym: γ-Butyrobetaine hydrochloride,(3-Carboxypropyl)trimethylammonium chlor

Target: Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00714	CD5L Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CD5L Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38 kDa and the accession number is Q9QWK4.
TMPH-02756	LECT2 Protein, Mouse, Recombinant (His & Myc)	Mouse	P. pastoris (Yeast)
	LECT2 Protein, Mouse, Recombinant (His & Myc) is expressed in Yeast.
TMPH-02755	LECT2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation. LECT2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular ...
TMPH-02183	CCT2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating t...
TMPY-03811	KCT2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C5orf15 (Chromosome 5 Open Reading Frame 15, also known as KCT2) is a Protein Coding gene. KCT2 gene maps to human chromosome 5q31.1 and is conserved in human, chimpanzee, cow, rat, and chicken. KCT2 is a 265 amino acid ...