Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,820.00 | |
50 mg | 8-10 weeks | $ 2,380.00 | |
100 mg | 8-10 weeks | $ 3,100.00 |
Description | CCT251455 is an inhibitor of mitotic kinase monopolar spindle 1 (MPS1; IC50: 3 nM). |
Targets&IC50 | Mps1:3 nM |
In vitro | CCT251455 is a highly potent inhibitor of MPS1 that demonstrates high selectivity versus kinases tested in a broad kinome profiling panel. CCT251455 inhibits P-MPS1 (IC50: 0.04 μM in the cell-based assay; GI50: 0.16 μM). |
In vivo | CCT251455 demonstrates a good oral pharmacokinetic profile in mice and rats as well as inhibition of MPS1 activity in vivo following oral administration. |
Molecular Weight | 503.98 |
Formula | C26H26ClN7O2 |
CAS No. | 1400284-80-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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CCT251455 1400284-80-1 Cytoskeletal Signaling Kinesin CCT-251455 CCT 251455 inhibitor inhibit