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Search Result

Search Results for " cox2 "

Targets

Others COX Autophagy

17

Compounds

2

Natural Products

2

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T7882 Indomethacin farnesil Infree Others , COX , Autophagy
Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug (DMARD).
T12860 SC57666 COX
SC57666 is a highly selective COX2 inhibitor (IC50 at 26 nM) that shows no activity against COX1.
T15687 Thioflosulide L-745337 COX
Thioflosulide (L-745337) is a selective and potent COX2 inhibitor (IC50: 2.3 nM) with anti-inflammatory activity for the study of gastric ulcers.
T10355 Apyramide COX
Apyramide is an anti-inflammatory agent (NSAID) and behaves as a prodrug of indomethacin. Indomethacin is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2.
T10032 COX-2-IN-2 COX
COX-2-IN-2, a selective inducible COX2 inhibitor, exhibits potent inhibition with an IC50 of 0.24 μM. Meanwhile, COX-2-IN-1 functions as an anti-inflammatory agent, demonstrating both anti-inflammatory and analgesic acti...
T23046 N-tert-butyl-α-Phenylnitrone (Z)-N-benzylidene-2-Methylpropan-2-aMine oxide ROS , COX
N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity. N-tert-butyl-α-Phenylnitrone((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) possesses potent reactive oxyge...
T0961 Trometamol Tromethamine COX
Trometamol (Tromethamine) is a proton acceptor used to treat acidemia. It inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inflammatory pro-prostagland...
T15571 Imrecoxib BAP-909 COX
Imrecoxib (BAP-909) is a novel and selective cyclooxygenase 2 (COX-2) inhibitor (IC50: 18 nM). It also inhibits COX1- activity (IC50: 115 nM). Imrecoxib has an anti-inflammatory effect.
T1562 Rebamipide Proamipide,OPC12759 Free radical scavengers , COX , Prostaglandin Receptor
Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis ...
T0458 Indomethacin Indocin,Indometacine,Indomethacine,Indometacin Phospholipase , COX , PDE , Autophagy
Indomethacin (Indometacin) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of indomethacin is as a Cyclooxygenase Inhibitor.
T69138 GW-406381X
GW-406381X is a cyclooxygenase-2 (COX2) inhibitor.
T12802 (S)-Ketorolac (-)-Ketorolac Others
(S)-Ketorolac is a potent inhibitor of COX1 and COX2 enzyme, and is nonsteroidal anti-inflammatory agent.
T11655 Indomethacin-D4 Indometacin-D4 CDK
Indomethacin-D4 is a deuterium labeled Indomethacin. Indomethacin is a potent and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells.
T70431 TX-1123
TX-1123 is a potent inhibitor of protein tyrosine kinase (PTK), specifically targeting Src, eEF2-K, PKA, and EGFR-K/PKC. Additionally, it acts as a cyclo-oxygenase (COX) inhibitor, displaying IC50 values of 1.16 μM for C...
T1780L Parecoxib sodium SC 69124A,SC-69124A,SC69124A,Dynastat
Parecoxib is a cyclooxygenase-2 inhibitor used for the short-term treatment of postoperative pain in adults. Parecoxib is a water-soluble and injectable prodrug of valdecoxib. Parecoxib is a COX2 selective inhibitor in t...
T63768 Antitumor agent-78
Antitumor agent-78 inhibits GPx-4 and elevates COX2, leading to ferroptosis. antitumor agent-78 activates the tumor cell intrinsic apoptotic pathway (Bax-Bcl-2-caspase-3) and inhibits the epithelial mesenchymal transitio...
T62814 Antitumor agent-77
Antitumor agent-77 inhibits the growth and migration of cancer cells and has anticancer effects. antitumor agent-77 inhibits GPx-4 and enhances COX2-induced iron sagging. antitumor agent-77 activates the intrinsic apopto...
Cat No. Product Name Synonyms Targets
T3S0645 N-trans-Feruloyltyramine Feruloyltyramine,N-Feruloyltyramine,Moupinamide Others , COX
1. N-trans-Feruloyltyramine (Feruloyltyramine)(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes, thereby suppressing P-s...
TN4860 Pueroside B COX , PPAR
Pueroside B may can treat coronary heart disease, it can interact with two or more targets[peroxisome proliferator activated receptor γ (PPAR-γ), angiotensin-converting enzyme (ACE), hydroxymethylglutaryl coenzyme A rece...

Natural Products

N-trans-Feruloyltyramine
T3S0645
Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide
Target: Others, COX
Pueroside B
TN4860
Synonym:
Target: COX, PPAR

Recombinant Proteins

Species：
Human (2)
Expression System：
Baculovirus Insect Cells (2)
Tag：
His (1)
N-10xHis, C-GST (1)
Cat No. Product Name Species Expression System
TMPY-01736 COX-2 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a perox...
TMPH-01552 IRF1 Protein, Human, Recombinant (GST & His) Human Baculovirus Insect Cells
Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections,...
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