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Search Result

Search Results for " cig "

Targets

Guanylate cyclase

22

Compounds

7

Natural Products

7

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T1984 Cinaciguat BAY 58-2667 Guanylate cyclase
Cinaciguat (BAY 58-2667) (BAY 58-2667) is the first of a new class of soluble guanylate cyclase (sGC) activators in Clinicalal development for acute decompensated heart failure.
T19023 Lucigenin NSC-151912,L-6868 Others
Lucigenin (NSC-151912) (L-6868) is a chemiluminescent probe used to indicate the presence of endogenously generated superoxide anion radicals in cells.
T16383 Olinciguat IW-1701 Guanylate cyclase
Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator. It also has concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole-cell assay.
T19710 Ciglitazone Ciglitazona,U 63287,ADD3878,ADD-3878,U-63287,ADD 3878 Apoptosis , p38 MAPK , PPAR
Ciglitazone (ADD 3878) is a potent and selective PPARγ agonist (EC50: 3 μM) and oral hypoglycemic agent. Ciglitazone inhibits proliferation and differentiation of th17 cells, decreases insulin levels, vascular endothelia...
T6968 Riociguat BAY 632521 Guanylate cyclase
Riociguat (BAY 632521) is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension.
T16569 Praliciguat IW-1973 Others , Guanylate cyclase
Praliciguat (IW-1973) stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator.
T21607 Ataciguat HMR-1766 Others , Guanylate cyclase
Ataciguat (HMR-1766) (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.
T4381 Lificiguat YC-1 Others , Guanylate cyclase , HIF
Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha).
T7201 Nelociguat BAY60-4552 Guanylate cyclase
Nelociguat (BAY60-4552)(BAY60-4552) is a soluble guanylate cyclase stimulator (sGC stimulator). Soluble guanylate cyclase (sGC) is a key enzyme in the nitric oxide (NO) signalling pathway.
T17226 Vericiguat BAY1021189 Guanylate cyclase
Vericiguat (BAY1021189) is a potent and orally available guanylate cyclase stimulator.
T16808 Runcaciguat Others , Guanylate cyclase
Runcaciguat is a soluble guanylate cyclase stimulator. Runcaciguat combines with selective partial adenosine A1 receptor agonists and can be used in studies about cardiovascular and renal diseases.
T123930 Tenacigenoside A
Tenacigenoside A is a useful organic compound for research related to life sciences and the catalog number is T123930.
T27043 Clociguanil
Clociguanil has antimalarial activity.
T1984L Cinaciguat hydrochloride BAY582667,BAY58-2667,BAY 582667,BAY-582667,BAY 58-2667,BAY-58-2667,Cinaciguat HCl
Cinaciguat( BAY582667, BAY58-2667) is a soluble guanosine cyclase activator that can prevent cardiac dysfunction in rat models of type 1 diabetes.
T125784 Crucigasterin 277
T125782 Crucigasterin 225
T39723 Mosliciguat
Mosliciguat is a guanylate cyclase activator.
T32928 Lucigenol
Lucigenol is a bioactive chemical.
T32663 Leuciglumer Leuciglumero,Leuciglumere
Leuciglumer is a bioactive chemical.
T39673 Zagociguat
Zagociguat is a soluble guanylate cyclase stimulator that enhances nitric oxide (NO) signaling, resulting in increased production of cyclic guanosine monophosphate. This compound shows promise for investigating non-centr...
T125783 Crucigasterin 275
T33670 Nigrescigenin Canescegenine,Canescegenin,Sarmentosigenin A
Nigrescigenin is a cardenolide from Parquetina nigrescens.
Cat No. Product Name Synonyms Targets
TN2107 Protoescigenin Others
Protoescigenin is from horse chestnut saponin mixture and can be used as the substrate for exploratory chemistry towards selective protection.
TN2206 Shancigusin I Others
Shancigusin I is a natural product from the tuber of Cremastra appendiculata.
TN6576 3-Methoxyshancigusin I
3-Methoxyshancigusin I can be used in related research in the field of life sciences, and its product number is TN6576.
TN2577 11,12-Di-O-acetyltenacigenin B Others
11,12-Di-O-acetyltenacigenin B is a natural product for research related to life sciences. The catalog number is TN2577 and the CAS number is 857897-01-9.
T2S1841 3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B Tenacigenin B, 3-O-β-Allopyranosyl-(1→4) Others
Tenacigenin B, a component of the plant Poria cocos, is identified as 3-O-β-Allopyranosyl-(1→4).
TN2263 Tenacigenin B P-gp
Tenacigenin B is a natural product of Marsdenia, Asclepiadaceae. The catalog number is TN2263 and the CAS number is 80508-42-5. Tenacigenin B can be used as a reference standard.
T83459 11α-O-Tigloyl-12β-O-acetyltenacigenin B Aurora Kinase
11α-O-Tigloyl-12β-O-acetyltenacigenin B, an ester derivative isolated from Garcinia cambogia (MTC), modulates the antitumor effects of Aurora-A in lymphoma through its parent compound, Tenacigenin B.

Natural Products

Protoescigenin
TN2107
Synonym:
Target: Others
Shancigusin I
TN2206
Synonym:
Target: Others
3-Methoxyshancigusin I
TN6576
Synonym:
Target:
11,12-Di-O-acetyltenacigenin B
TN2577
Synonym:
Target: Others
3-O-beta-Allopyranosyl-(1->4)-beta-oleandropyranosyl-11-O-isobutyryl-12-O-acetyltenacigenin B
T2S1841
Synonym: Tenacigenin B, 3-O-β-Allopyranosyl-(1→4)
Target: Others
Tenacigenin B
TN2263
Synonym:
Target: P-gp
11α-O-Tigloyl-12β-O-acetyltenacigenin B
T83459
Synonym:
Target: Aurora Kinase

Recombinant Proteins

Species：
Human (7)
Expression System：
HEK293 (6)
E. coli (1)
Tag：
C-His (3)
His (2)
C-hFc (1)
None (1)
Cat No. Product Name Species Expression System
TMPJ-01430 NovoNectin Protein, Human, Recombinant Human E. coli
Fibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of ~63 kDa containin...
TMPY-00803 Fibronectin Protein, Human, Recombinant (aa 607-1265, His) Human HEK293
Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet ...
TMPK-01389 Fibronectin Protein, Human, Recombinant (aa 32-345, His) Human HEK293
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells ...
TMPK-01373 Fibronectin Protein, Human, Recombinant (aa 1266-1356, hFc) Human HEK293
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells ...
TMPY-05562 Fibronectin Protein, Human, Recombinant (aa 1722-1811, His) Human HEK293
Fibronectin (FN) is a glycoprotein component of the extracellular matrix of the extracellular matrix (ECM) with roles in embryogenesis, development, and wound healing. More recently, FN has emerged as player in platelet ...
TMPK-01390 Fibronectin Protein, Human, Recombinant (aa 32-602, His) Human HEK293
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells ...
TMPK-01391 Fibronectin Protein, Human, Recombinant (aa 1266-1356, His) Human HEK293
Fibronectin is a high molecular glycoprotein present in the blood, connective tissue and at cell surface. It is synthesized by many types of differentiated cells and is believed to be involved in the attachment of cells ...
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