bleomycin — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6116L	Bleomycin hydrochloride		DNA/RNA Synthesis
	Bleomycin hydrochloride is a potent antitumor antibiotic that functions as a DNA synthesis inhibitor and DNA damaging agent.		DNA/RNA Synthesis
T6116	Bleomycin Sulfate	Blenoxane,NSC125066	DNA/RNA Synthesis , Antibiotic
	Bleomycin Sulfate (Blenoxane) is a glycopeptide antibiotic, an inhibitor of DNA synthesis. Bleomycin Sulfate causes DNA strand breaks but not RNA strand breaks. Bleomycin Sulfate has antitumor activity.		DNA/RNA Synthesis , Antibiotic
T75508	Bleomycin A5
	Bleomycin A5 (Pingyangmycin), a glycopeptide antibiotic that is orally active, functions as an antineoplastic agent, an apoptosis inducer, and a bacterial metabolite [1] [2].
T73606	Bleomycin B4
	Bleomycin B4 (Phleomycin F), an antibiotic with antitumor properties, is utilized in cancer research [1] [2] [3].
T65016	Bleomycin A2
	Bleomycin A2, a DNA-degrading antitumor antibiotic, functions as an inhibitor of aspartate/asparagine-β-hydroxylase (AspH), exhibiting an inhibitory concentration (IC 50) of 1.47 μM [1].
T74722	Demethyl bleomycin A2
	Demethyl bleomycin A2 is a Bleomycin congener. The DNA cleavage of demethyl bleomycin A2 is insensitive to the presence of 5-Methylcytidine [1] .
T71445	Bleomycin Free Base
	Bleomycin Free Base is a complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumo...
T10110	3-CPs	3-Carbethoxypsoralen,3-Ethoxycarbonylpsoralen	Antibiotic
	3-CPs (3-Carbethoxypsoralen) is a bleomycin-induced serotypic podoplanar polysaccharide in mouse lung fibrosis that belongs to the psoralen family and interferes with antibody-mediated bacterial killing.3-CPs delays bleo...		Antibiotic
T6S0105	Peiminine	Zhebeinone,Fritillarine,Raddeanine,Verticinone	Others , Autophagy
	1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.		Others , Autophagy
T21498	Phleomycin		DNA/RNA Synthesis , Antibacterial , Antibiotic
	Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.		DNA/RNA Synthesis , Antibacterial , Antibiotic
T36416	N1-Acetylspermine trihydrochloride	N1-Acetylspermine (hydrochloride)	Others
	N1-Acetylspermine trihydrochloride is a monoacetylated derivative of spermine which is an endogenous polyamine. N1-Acetylspermine trihydrochloride can be used in studies about the uptake of the anticancer polyamine anal...		Others
T30778	CCG-257081	MRTF/SRF-IN-1,CCG257081,CCG 257081	Rho , Ras
	CCG-257081 (MRTF/SRF-IN-1) is an inhibitor of cardiac myosin-related transcription factor and serum response factor (MRTF/SRF) that acts by inhibiting the Rho/MRTF/SRF pathway.CCG-257081 has shown efficacy in preventing ...		Rho , Ras
T4953	Neotuberostemonine		NOS
	Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruit...		NOS
T2S0690	Ecliptasaponin A	Echinocystic acid-3-o-glucoside	Others
	1. Ecliptasaponin A (Echinocystic acid-3-o-glucoside) has protective effects against the pulmonary fibrosis induced by bleomycin via reducing the oxidative stress, lung tissue inflammation, and the subsequent epithelial-...		Others
T2762	Kasugamycin hydrochloride	Kasumin	Antibacterial , Antibiotic , Antifungal
	Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydr...		Antibacterial , Antibiotic , Antifungal
TN3469	Aucuparin	2,6-dimethoxy-4-phenylphenol	NADPH-oxidase
	Aucuparin (2,6-dimethoxy-4-phenylphenol) is a plant antibiotic with anti-inflammatory activity. Aucuparin inhibited pulmonary fibrosis in mouse models induced by bleomycin (BLM). ABTS and FRAP showed clear scavenging act...		NADPH-oxidase
T3795	Corilagin		Apoptosis , TLR , Reverse Transcriptase , Antibacterial , Autophagy
	Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B...
T28177	NK3201	NK-3201,NK 3201
	NK3201, a specific chymase inhibitor, suppresses bleomycin-induced pulmonary fibrosis in hamsters.
T73662	Peplomycin
	Peplomycin (Bleomycin PEP; Pepleomycin), an analogue of Bleomycin, exhibits significant antitumor activity with reduced pulmonary toxicity. It induces apoptosis in the oral squamous carcinoma cell line SSCKN and causes p...
TN5879	Edgeworin
	Edgeworin is a DNA polymerase beta (pol beta) inhibitor, it inhibits both the lyase and polymerase activities of DNA polymerase beta; it can potentiate the inhibitory action of the anticancer drug bleomycin in cultured A...