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Search Results for " azd9291 "

7

Compounds

Cat No. Product Name Synonyms Targets
T30268 AZD9291-345 AZD-9291345,AZD 9291345,AZD9291345
AZD9291-345 is a compound which has a molecule weight 345, and structurally related to AZD9291.
T16162 Mutated EGFR-IN-1 Osimertinib analog EGFR
Mutated EGFR-IN-1 (Osimertinib analog) is a useful intermediate for the inhibitors design for mutated EGFR, such as L858R EGFR, Exonl9 deletion activating mutant, and T790M resistance mutant.
T2490 Osimertinib AZD-9291,Mereletinib EGFR
Osimertinib (AZD-9291) is an EGFR third-generation inhibitor that inhibits the T790M resistance mutation produced by second-generation EGFR inhibitors with irreversible and oral activity. Osimertinib has antitumor activi...
T3634 Osimertinib mesylate Mereletinib mesylate,AZD-9291 mesylate EGFR
Osimertinib mesylate (Mereletinib mesylate) is an irreversible and mutant selective EGFR inhibitor (IC50s: 12/1 nM for EGFR(L858R) and EGFR(L858R/T790M)).
T10433 Osimertinib dimesylate Mereletinib (dimesylate),AZD-9291 (dimesylate) EGFR
Osimertinib dimesylate is an irreversible and mutant selective EGFR inhibitor (IC50s: 12 and 1 nM against EGFR L858R and EGFR L858R/T790M).
T13564 AZ7550 MLK , FAK , EGFR , FLT , Tyrosine Kinases , PYK2 , MNK , IGF-1R , ACK , BTK , ALK , Drug Metabolite
AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
T13564L AZ7550 hydrochloride AZ7550 hydrochloride (1421373-99-0 free base) EGFR , IGF-1R
AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
TargetMol