acp — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T14116	ACP-105		Androgen Receptor
	ACP-105 is a novel and potent nonsteroidal selective androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone.		Androgen Receptor
T2076	Pimavanserin	ACP-103	5-HT Receptor
	Pimavanserin (ACP-103)(ACP-103) is an effective and specific 5-HT2A receptor inverse agonist (mean pIC50: 8.7, in the cell-based functional assay). Pimavanserin is an atypical antipsychotic used in the treatment of hallu...		5-HT Receptor
T6946	Pimavanserin tartrate	ACP-103,ACP-103 tartrate,Nuplazid,Pimavanserin	5-HT Receptor
	Pimavanserin tartrate (Nuplazid) is an effective and specific serotonin 5-HT2A inverse agonist (pIC50: 8.73), used in the therapy of psychosis associated with Parkinson's disease.		5-HT Receptor
T3626	Acalabrutinib	ACP-196	BTK
	Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and pre...		BTK
T29614	ACP-0052	SL052,SL 052,SL-052,ACP 0052
	ACP-0052(SL-052, ACP-SL-052) is a photosensitizer based on hypoclintin that may be used in the treatment of prostate cancer.
T10240	ACP-5862		BTK
	ACP-5862 is a major active and pyrrolidine ring-opened metabolite of Acalabrutinib (IC50: 5.0 nM for BTK). Acalabrutinib is an irreversible and highly selective BTK inhibitor (IC50: 3 nM; EC50: 8 nM).		BTK
TP1837	Acyl Carrier Protein (ACP) (65-74)	Acyl Carrier Protein (ACP) 65-74
	Acyl Carrier Protein (ACP) (65-74) is an active acyl carrier protein (ACP) fragment.Acyl Carrier Protein (ACP) is a component of plastid-located plant fatty acid synthetase. It binds acyl groups covalently via the prosth...
T3484	Trans-ACPD	Trans-(±)-ACP,1-amino-1,3-dicarboxycyclopentane,(±)-trans-ACPD	GluR
	trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD. trans-ACPD is a selective agonist of the mGluR (metabotropic glutamate receptor); active at the group I/II mGlu receptors (EC50: 2/1...		GluR
T34657	SL-017	ACPSL-017,S-017,ACP-SL-017,ACP-SL017
	SL-017 (ACP-SL-017, ACPSL-017, ACP-SL-017) is a Hypocrellin-B (Hb) derivative and photosensitization agent that may be used to treat abnormal hair growth. SL017 targets the mitochondria and causes the mitochondrial membr...
T71732	Fmoc-ε-Acp-OH
	Fmoc-ε-Acp-OH can be used as a PROTAC linker in the synthesis of PROTACs and other conjugation applications. Fmoc-ε-Acp-OH is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group ...
T70840	Osemozotan Free Base
	Osemozotan Free Base is a 5-HT(1A) receptor agonist.
T4852	Trimyristin	Trimyristoylglycerol,Tritetradecanoin,Glyceryl trimyristate,1,2,3-Tritetradecanoylglycerol	Phosphatase , Endogenous Metabolite , AChE
	Trimyristin (Tritetradecanoin) is primarily located in the membrane (predicted from logP) and adiposome. glyceryl trimyristate exists in all eukaryotes, ranging from yeast to humans. In humans, glyceryl trimyristate is i...		Phosphatase , Endogenous Metabolite , AChE
TP1427L	ReACp53 acetate		p53
	ReACp53 acetate could inhibit p53 amyloid formation and rescue p53 function in cancer cell lines.		p53
T75171	BacPROTAC-1
	BacPROTAC-1, a potent mSA BacPROTAC degrader, exhibits high affinity for both mSA and the N-terminal domain (NTD) of ClpC, with dissociation constants (K D) of 3.9 μM and 2.8 μM, respectively [1].
T19178	ACPK		Others
	ACPK is a pyrrolysine analogue bearing an azide residue.		Others
T70842	ACP1b
	ACP1b is an activator of ClpP protease.
T75168	Homo-BacPROTAC7
	Homo-BacPROTAC7, a ClpC1 NTD BacPROTAC degrader, targets ClpC2 and efficiently kills M. tuberculosis [1].
TP1427	ReACp53
	ReACp53 is a cell-penetrating peptide, designed to inhibit p53 amyloid formation, resues p53 function in cancer cell lines and in organoids derived from high-grade serous ovarian carcinomas (HGSOC).
T75167	Homo-BacPROTAC6
	Homo-BacPROTAC6, a ClpC1 NTD BacPROTAC degrader, effectively targets ClpC2, while Homo-BacPROTAC7 has been shown to efficiently kill M. tuberculosis [1].
T22488	(1S,3R)-ACPD		Others
	(1S,3R)-ACPD is a group I and II mGlu receptor agonist.		Others