aad — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T27084	Crisdesalazine	AAD2004,AAD 2004,AAD-2004	Prostaglandin Receptor
	Crisdesalazine (AAD 2004) is an inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1). Crisdesalazine reduces autophagosome formation, axonopathy, and motor neuron degeneration, improving motor function and incre...		Prostaglandin Receptor
T25894	NVP-AAD777	AAD-777,NVP-AAD-777,NVP AAD 777
	NVP-AAD777 is a specific VEGFR-2 inhibitor.
T16126	Monepantel	AAD1566,PPL-1	AChR
	Monepantel (AAD1566) is an organic anthelmintic and nicotinic acetylcholine receptor antagonist from roundworms and esophagostomies that is widely used for de-worming in agriculture and livestock.		AChR
T18906	7-Aminoactinomycin D	7-AAD	Others
	7-Aminoactinomycin D is a fluorescent DNA stain.		Others
T80745	Z-Ala-Ala-Asp-CMK	Z-AAD-CMK	Caspase
	Z-Ala-Ala-Asp-chloromethylketone (Z-AAD-CMK) is a selective inhibitor of granzyme B [1].		Caspase
T81176	Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2
	Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2 is a biologically active peptide. Structure-activity studies of the thrombin receptor-tethered ligand SFLLRNP underscored the pivotal role of the Phe-2-phenyl group in receptor r...
T20042	8-Azaadenine	NSC 32797,NSC32797,NSC-32797	Xanthine Oxidase
	8-Azaadenine (NSC-32797) is an inhibitor of xanthine oxidase with IC50 of 0.54 μM and Ki of 0.66 μM.		Xanthine Oxidase
T77505	Cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride	Quaternium-15 cis-form
	cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride (Quaternium-15 cis-form) is an antimicrobial agent used in cosmetics as a cosmetic preservative and antistatic agent.cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azo...
T9111	8-Azaadenosine		Adenosine deaminase
	8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells.		Adenosine deaminase
T33565	NAAD sodium salt	NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD
	NAAD sodium salt (NAAD Na salt) is a substrate of nicotinamide adenine dinucleotide synthase and can be used in studies about the specificity and kinetics of the substrate.
T10111	3-Deazaadenosine hydrochloride		Others , HIV Protease
	3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 µM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.		Others , HIV Protease
TNU1263	N-1H-imidazo[4,5d ]pyridazin-7-yl benzamideN4-Benzoyl-2-aza-3’-deazaadenine
	N-1H-imidazo[4,5d ]pyridazin-7-yl benzamideN4-Benzoyl-2-aza-3'-deazaadenine is a Heterocyclic Compound - Purine; Intermediates and Building Blocks - Nucleoside bases.
T35922	NAADP (sodium salt)
	Nicotinic acid adenine dinucleotide phosphate (NAADP) is a secondary messenger that induces calcium mobilization. It induces calcium release from endosomes and lysosomes via two-pore channel 2 (TPC2) and TPC1, which then...
T35558	KAAD-Cyclopamine
	Cyclopamine-KAAD is a potent inhibitor of hedgehog signaling with an IC50 value of 20 nM in a Shh-LIGHT2 assay. It blocks binding of BODIPY-cyclopamine to cells expressing Smoothened (Smo) in a dose-dependent manner. Cyc...
T38533	7-Iodo-2',3'-dideoxy-7-deazaadenosine
	7-Iodo-2',3'-dideoxy-7-deazaadenosine is a dideoxynucleoside compound with applications in DNA synthesis and sequencing reactions.
T83224	AADvac 1
	AADvac1 is a biologically active peptide functioning as an Alzheimer's Disease Peptide Vaccine, composed of Tau(294–305) conjugated to Keyhole Limpet Hemocyanin (KLH).
T33913	Pentaerythrityl tetraadipate
	Pentaerythrityl tetraadipate is a bioactive chemical.
T83801	ε-NAADP+ sodium	Etheno-NAADP,β-Nicotinic Acid-1,N6-Ethenoadenine dinucleotide phosphate,Nicotinic Acid adenine dinucleotide phosphate
	ε-NAADP+ is a fluorescent derivative of NAADP, known for inducing calcium mobilization. It effectively induces calcium release in sea urchin egg homogenates with an EC50 of 5 µM. The compound exhibits excitation and emis...
T10111L	3-Deazaadenosine		HIV Protease
	3-Deazaadenosine is an inhibitor of S-adenosylhomocysteine hydrolase, with a Ki of 3.9 µM, and it has anti-inflammatory, anti-proliferative and anti-HIV activity.		HIV Protease
T78426	MCAAD-3
	MCAAD-3, a near-infrared Aβ imaging probe, exhibits blood-brain barrier permeability and strong affinity for Aβ polymers (Ki >106 nM). It successfully labels Aβ plaques in the brains of transgenic mice [1].
T23049	NAADP tetrasodium salt		Others
	Ca2+ mobilizing agent		Others
T10015	1-Deazaadenosine		Others
	1-Deazaadenosine is a potent Adenosine deaminase inhibitor (Ki: 0.66 μM). It exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders.		Others

Compounds

Crisdesalazine

T27084

Synonym: AAD2004,AAD 2004,AAD-2004

Target: Prostaglandin Receptor

NVP-AAD777

T25894

Synonym: AAD-777,NVP-AAD-777,NVP AAD 777

Target:

Monepantel

T16126

Synonym: AAD1566,PPL-1

Ser-parafluoroPhe-Aad-Leu-Arg-Asn-Pro-NH2

Synonym: NSC 32797,NSC32797,NSC-32797

Target: Xanthine Oxidase

cis-1-(3-Chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride

T77505

Synonym: Quaternium-15 cis-form

Target: Adenosine deaminase

NAAD sodium salt

T33565

Synonym: NAAD Na salt,Deamido Nad Sodium Salt,NAAD Na, NaAD

Target:

3-Deazaadenosine hydrochloride

T10111

Synonym:

Target: Others, HIV Protease

N-1H-imidazo[4,5d ]pyridazin-7-yl benzamideN4-Benzoyl-2-aza-3’-deazaadenine

7-Iodo-2',3'-dideoxy-7-deazaadenosine

Pentaerythrityl tetraadipate

Synonym: Etheno-NAADP,β-Nicotinic Acid-1,N6-Ethenoadenine dinucleotide phosphate,Nicotinic Acid adenine dinucleotide phosphate

NAADP tetrasodium salt

Cat No.	Product Name	Synonyms	Targets
T83789	7-Deazaadenosine-5'-O-diphosphate sodium	7-CH-ADP,Tubercidin 5’-diphosphate,TuDP
	7-Deazaadenosine-5'-O-diphosphate, a modified nucleotide and metabolite of tubercidin, is generated through phosphorylation of tubercidin and further undergoes phosphorylation to become the active metabolite 7-deazaadeno...

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPH-00404	Acetoacetate decarboxylase Protein, Clostridium acetobutylicum, Recombinant (His)	Clostridium acetobutylicum	Baculovirus Insect Cells
	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide. Acetoacetate decarboxylase Protein, Clostridium acetobutylicum, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The pre...
TMPH-01596	AADAT Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a vari...
TMPH-00959	AADAC Protein, Human, Recombinant (His & Myc & SUMO)	Human	E. coli
	AADAC Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPY-00510	FKBP11 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	FKBP11 serve as biomarker and/or therapeutic target for Acute aortic dissection (AAD). FKBP11 during the development of HCC and FKBP11 has the potential to be an early marker for HCC.