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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10169 | 5-HT4 antagonist 1 | 5-HT Receptor | |
5-HT4 antagonist 1 is an antagonist of 5-HT4 (pKi = 9.6). | |||
T5336 | Zacopride hydrochloride | Potassium Channel , 5-HT Receptor | |
Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist. | |||
T21946 | BIMU 8 | 5-HT Receptor | |
BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4. | |||
T1291 | Cisapride | Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase | Potassium Channel , 5-HT Receptor , HER |
Cisapride (R 51619) is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote intestinal peristalsis, increase gastric emptying and decrease... | |||
T22992 | ML 10302 hydrochloride | 5-HT Receptor | |
ML 10302 hydrochloride is a specific agonist 5-HT4 and binds 5-HT receptors with Kis of 1.07 nM and 782 nM for 5-HT4 and 5-HT3. | |||
T38507 | Renzapride | BRL 24924 | 5-HT Receptor |
Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist.Renzapride can be used in the study of constipation-predominant irritable bowel syndrome (C-IBS). | |||
T22671 | CJ 033466 | 5-HT Receptor | |
CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect. | |||
T27117 | DA-6886 | DA6886,DA 6886 | 5-HT Receptor |
DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressin... | |||
T33940 | PF-03382792 | PF 03382792,PF03382792 | 5-HT Receptor |
PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease. | |||
T28934 | Felcisetrag | TD 8954,TD8954,TD-8954 | 5-HT Receptor |
Felcisetrag (TD-8954) is a potent and selective orally active 5-HT4 agonist with gastrointestinal prokinetic properties.Felcisetrag shows high affinity for the human recombinant 5-HT4(c) (h5-HT4(c)) receptor with a pKi o... | |||
T6958 | Prucalopride Succinate | R-108512,Resolor Succinate | 5-HT Receptor |
Prucalopride Succinate (Resolor Succinate) is a selective, high affinity 5-HT4 receptor agonist, inhibiting human 5-HT(4a) and 5-HT(4b) receptor with Ki value of 2.5 nM and 8 nM, respectively. | |||
T15414 | GR 113808 | GR-113808 | 5-HT Receptor |
GR 113808 is a selective 5-HT4 receptor antagonist that inhibits 5-HT1B, 5-HT2A, 5-HT2C, and 5-HT3 receptors, and attenuates dopamine release. | |||
T23310 | SB-203186 hydrochloride | 5-HT Receptor | |
SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist | |||
T68035 | Capeserod | SL-650155,SL-65.0155 | 5-HT Receptor |
Capeserod is a potential 5-HT4 receptor (5-hydroxytryptamine receptor 4) agonist for the study of digestive disorders and neurological disorders. | |||
T28043L | Minesapride | 5-HT Receptor | |
Minesapride, a novel 5-hydroxytryptamine 4 (5-HT4) receptor partial agonist, is a potential gastrointestinal prokinetic agent for the treatment of irritable bowel syndrome with constipation. | |||
T68116L | (Rac)-Norcisapride | 5-HT Receptor | |
Norcisapride is a 5-hydroxytryptamine receptor 3 (5-HT3) and (5-hydroxytryptamine receptor 4 (5-HT4) dual agonist used for the treatment of gastrointestinal disorders, orofacial disorders, and otorhinolaryngologic disord... | |||
T13021 | Sulamserod | RS-100302 | 5-HT Receptor |
Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related diseases. | |||
T21385 | Cinitapride | Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove | 5-HT Receptor |
Cinitapride (Blaston) is a gastroprokinetic agent. It slows the actions of the muscles to reduce the symptoms of conditions such as acid reflux, delayed gastric emptying, and ulcer dyspepsia. Cinitapride acts as an antag... | |||
T2278 | Piboserod | SB-207266 | 5-HT Receptor |
Piboserod (SB-207266) (SB 207266) is a selective 5-HT(4) receptor antagonist. | |||
T23265 | RS 67333 hydrochloride | RS 67333 (hydrochloride),RS 67333 HCl | 5-HT Receptor |
RS 67333 hydrochloride (RO5203648) is a potent, selective partial agonist of the 5-HT4 receptor (5-HT4R) with a pKi value of 8.7 in guinea-pig striatum. It demonstrates lower binding affinities for other receptors, inclu... |