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Search Results for " 5-ht4 "

20

Compounds

Cat No. Product Name Synonyms Targets
T10169 5-HT4 antagonist 1 5-HT Receptor
5-HT4 antagonist 1 is an antagonist of 5-HT4 (pKi = 9.6).
T5336 Zacopride hydrochloride Potassium Channel , 5-HT Receptor
Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.
T21946 BIMU 8 5-HT Receptor
BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.
T1291 Cisapride Prepulsid,R 51619,Pridesia,Kaudalit,(±)-Cisaprid,Kinestase Potassium Channel , 5-HT Receptor , HER
Cisapride (R 51619) is a serotonin type 4 (5-HT4) receptor agonists are potent prokinetic agents that act on serotonin receptors in the intestine and promote intestinal peristalsis, increase gastric emptying and decrease...
T22992 ML 10302 hydrochloride 5-HT Receptor
ML 10302 hydrochloride is a specific agonist 5-HT4 and binds 5-HT receptors with Kis of 1.07 nM and 782 nM for 5-HT4 and 5-HT3.
T38507 Renzapride BRL 24924 5-HT Receptor
Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist.Renzapride can be used in the study of constipation-predominant irritable bowel syndrome (C-IBS).
T22671 CJ 033466 5-HT Receptor
CJ 033466 is a selective partial agonist of 5-HT4 receptor (EC50 = 9 nM) with gastroprokinetic effect.
T27117 DA-6886 DA6886,DA 6886 5-HT Receptor
DA-6886 is an agonist 5-Hydroxytryptamine receptor 4 (5-HT4). DA-6886 induced relaxation of the rat oesophagus preparation in a 5-HT4 receptor antagonist-sensitive manner. The evaluation of DA-6886 in CHO cells expressin...
T33940 PF-03382792 PF 03382792,PF03382792 5-HT Receptor
PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.
T28934 Felcisetrag TD 8954,TD8954,TD-8954 5-HT Receptor
Felcisetrag (TD-8954) is a potent and selective orally active 5-HT4 agonist with gastrointestinal prokinetic properties.Felcisetrag shows high affinity for the human recombinant 5-HT4(c) (h5-HT4(c)) receptor with a pKi o...
T6958 Prucalopride Succinate R-108512,Resolor Succinate 5-HT Receptor
Prucalopride Succinate (Resolor Succinate) is a selective, high affinity 5-HT4 receptor agonist, inhibiting human 5-HT(4a) and 5-HT(4b) receptor with Ki value of 2.5 nM and 8 nM, respectively.
T15414 GR 113808 GR-113808 5-HT Receptor
GR 113808 is a selective 5-HT4 receptor antagonist that inhibits 5-HT1B, 5-HT2A, 5-HT2C, and 5-HT3 receptors, and attenuates dopamine release.
T23310 SB-203186 hydrochloride 5-HT Receptor
SB 203186 hydrochloride is a potent 5-HT4 receptor antagonist
T68035 Capeserod SL-650155,SL-65.0155 5-HT Receptor
Capeserod is a potential 5-HT4 receptor (5-hydroxytryptamine receptor 4) agonist for the study of digestive disorders and neurological disorders.
T28043L Minesapride 5-HT Receptor
Minesapride, a novel 5-hydroxytryptamine 4 (5-HT4) receptor partial agonist, is a potential gastrointestinal prokinetic agent for the treatment of irritable bowel syndrome with constipation.
T68116L (Rac)-Norcisapride 5-HT Receptor
Norcisapride is a 5-hydroxytryptamine receptor 3 (5-HT3) and (5-hydroxytryptamine receptor 4 (5-HT4) dual agonist used for the treatment of gastrointestinal disorders, orofacial disorders, and otorhinolaryngologic disord...
T13021 Sulamserod RS-100302 5-HT Receptor
Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related diseases.
T21385 Cinitapride Paxapride,Cidine,cinitapride tartrate,Blaston,Cintapro,Cinmove 5-HT Receptor
Cinitapride (Blaston) is a gastroprokinetic agent. It slows the actions of the muscles to reduce the symptoms of conditions such as acid reflux, delayed gastric emptying, and ulcer dyspepsia. Cinitapride acts as an antag...
T2278 Piboserod SB-207266 5-HT Receptor
Piboserod (SB-207266) (SB 207266) is a selective 5-HT(4) receptor antagonist.
T23265 RS 67333 hydrochloride RS 67333 (hydrochloride),RS 67333 HCl 5-HT Receptor
RS 67333 hydrochloride (RO5203648) is a potent, selective partial agonist of the 5-HT4 receptor (5-HT4R) with a pKi value of 8.7 in guinea-pig striatum. It demonstrates lower binding affinities for other receptors, inclu...
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