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PF-03382792

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Catalog No. T33940Cas No. 1400811-63-3
Alias PF03382792, PF 03382792

PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.

PF-03382792

PF-03382792

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Purity: 99.64%
Catalog No. T33940Alias PF03382792, PF 03382792Cas No. 1400811-63-3
PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$100In StockIn Stock
5 mg$252In StockIn Stock
10 mg$359In StockIn Stock
25 mg$538In StockIn Stock
50 mg$756In StockIn Stock
100 mg$987-In Stock
200 mg$1,370-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.64%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
PF-03382792 is a small molecule 5-HT4 receptor activator for the study of Alzheimer's disease.
Targets&IC50
5-HT4D receptor:2.7 nM (Ki), 5-HT4D receptor:0.9 nM (EC50)
SynonymsPF03382792, PF 03382792
Chemical Properties
Molecular Weight433.52
FormulaC23H32FN3O4
Cas No.1400811-63-3
SmilesC(NCC1CCN(CC2(O)CCOCC2)CC1)(=O)N3C=4C(C(C)(C)C3=O)=CC=C(F)C4
Relative Density.1.242 g/cm3 (Predicted)
Storage & Solubility Information
StorageIn solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 4.34 mg/mL (10.01 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3067 mL11.5335 mL23.0670 mL115.3349 mL
5 mM0.4613 mL2.3067 mL4.6134 mL23.0670 mL
10 mM0.2307 mL1.1533 mL2.3067 mL11.5335 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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