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Search Results for " 5-ht1a "

20

Compounds

Cat No. Product Name Synonyms Targets
T10168 5-HT1A modulator 1 5-HT1Amodulator1 Phospholipase , Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).
T37197 5-HT1A modulator 2 hydrochloride 5-HT Receptor
5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT , is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding[1]. [1]. Naiman, N.,et al. 2-(Alkylamino)tetralin derivatives: interaction with 5-HT1A serotoni...
T0280 Spiperone Spiroperidol,Spiropitan Dopamine Receptor
Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
TQ0311 GSK163090 Dopamine Receptor , 5-HT Receptor
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
T9272 Xaliproden hydrochloride Dopamine Receptor , 5-HT Receptor
Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.
T21011 Buspirone Buspirone free base,Ansial 5-HT Receptor
Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor.
T0162 Quetiapine ICI204636,Quetiapin Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antago...
T62843 5-HT1A antagonist 1
5-HT1A antagonist 1 (compound 6f) is a potent and selective 5-HT1Areceptor antagonist (Ki: 35 nM). 5-HT1A antagonist 1 can be used in the study of central nervous system disorders.
T22236 Alprenolol hydrochloride 5-HT Receptor
Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
T8593 RU 24969 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole 5-HT Receptor
RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.
T2132 Buspirone hydrochloride Buspirone HCl,Narol,Buspar Dopamine Receptor , 5-HT Receptor
Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).
T6241 Quetiapine hemifumarate Quetiapine Fumarate,ICI-204636 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.
T3046 BMY 7378 dihydrochloride BMY7378 HCl Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
BMY 7378 dihydrochloride (BMY7378 HCl) , α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.
T1045 Trimipramine maleate Surmontil maleate Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal...
T8136 Perospirone hydrochloride Perospirone HCl,SM-9018 hydrochloride Dopamine Receptor , 5-HT Receptor
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist.
T6647 Rotigotine- Neupro,N-0923,N-0437,SPM 962 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily transdermal patch, Rotigotine has not been associated with ser...
T7412 Tandospirone citrate SM-3997 citrate 5-HT Receptor
Tandospirone citrate (SM-3997 citrate) is a potent and selective 5-HT1A receptor partial agonist (Ki : 27 nM)
T0088 Urapidil hydrochloride Urapidil HCl 5-HT Receptor , Adrenergic Receptor
Urapidil hydrochloride (Urapidil HCl) is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist.
T7498 Eltoprazine hydrochloride DU 28853 hydrochloride 5-HT Receptor
Eltoprazine hydrochloride (DU 28853 hydrochloride) is a partial agonist at serotonin 5-HT1A, 5-HT1B, and 5-HT2B receptors (Ki value of 40, 52, and 81 nM, respectively).
T7281 F-15599 5-HT Receptor
F-15599 is a highly selective G-protein biased 5-HT1A receptor agonist(Ki : 3.4 nM).

Compounds

5-HT1A modulator 1
T10168
Synonym: 5-HT1Amodulator1
Target: Phospholipase, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
5-HT1A modulator 2 hydrochloride
T37197
Synonym:
Target: 5-HT Receptor
Spiperone
T0280
Synonym: Spiroperidol,Spiropitan
Target: Dopamine Receptor
GSK163090
TQ0311
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Xaliproden hydrochloride
T9272
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Buspirone
T21011
Synonym: Buspirone free base,Ansial
Target: 5-HT Receptor
Quetiapine
T0162
Synonym: ICI204636,Quetiapin
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor
5-HT1A antagonist 1
T62843
Synonym:
Target:
Alprenolol hydrochloride
T22236
Synonym:
Target: 5-HT Receptor
RU 24969
T8593
Synonym: 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Target: 5-HT Receptor
Buspirone hydrochloride
T2132
Synonym: Buspirone HCl,Narol,Buspar
Target: Dopamine Receptor, 5-HT Receptor
Quetiapine hemifumarate
T6241
Synonym: Quetiapine Fumarate,ICI-204636
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
BMY 7378 dihydrochloride
T3046
Synonym: BMY7378 HCl
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Trimipramine maleate
T1045
Synonym: Surmontil maleate
Target: Dopamine Receptor, 5-HT Receptor, Antibacterial, Adrenergic Receptor, Norepinephrine, Histamine Receptor
Perospirone hydrochloride
T8136
Synonym: Perospirone HCl,SM-9018 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor
Rotigotine-
T6647
Synonym: Neupro,N-0923,N-0437,SPM 962
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Tandospirone citrate
T7412
Synonym: SM-3997 citrate
Target: 5-HT Receptor
Urapidil hydrochloride
T0088
Synonym: Urapidil HCl
Target: 5-HT Receptor, Adrenergic Receptor
Eltoprazine hydrochloride
T7498
Synonym: DU 28853 hydrochloride
Target: 5-HT Receptor
F-15599
T7281
Synonym:
Target: 5-HT Receptor
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TargetMol